Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
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Research Abstract |
The vesicular glutamate transporter (VGLUT) is a member of the SLC17 family and transports glutamate into synaptic vesicles using a membrane potential as a driving force. VGLUT plays essential roles in glutamatergic signal transmission. The SLC17 family members are unique transporter which two distinct transport activity ,membrane potential driven anion transport and Na^+ gradient driven inorganic phosphate transport. In this study, we investigated functional mechanism and roles of SLC17 transporters.
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