| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Research Abstract |
The molecular mechanisms underlying development of Drosophila lamina and medulla optic ganglia have been studied. We have identified(1) cell surface molecules that are required for recognition between lamina precursor cells and retinal axons,(2) coordinated sequential action of the EGFR and Notch signaling pathways that induce medulla neuroblasts formation in a precisely ordered manner. We have also identified genes involved in planer cell polarity and actin remodeling as important players that regulate axon elongation and guidance of the mushroom body, the center of the olfactory memory formation.
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