| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
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| Research Abstract |
There are two different pathways in lysine biosynthesis. In this study, we have succeeded in elucidation of regulatory mechanisms of enzymes, each of which has a key role in each biosynthetic pathway. In the second half of lysine biosynthetic pathway throughα-aminoadipate, we discovered that a protein named LysW is not only used for modification of the amino group of the substrate, but also served as a carrier protein for biosynthetic enzymes.
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