| Project/Area Number |
21380165
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
古瀬 充宏 九州大学, 大学院・農学研究院, 教授 (30209176)
高橋 和昭 東北大学, 大学院・農学研究科, 准教授 (80183440)
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| Co-Investigator(Renkei-kenkyūsha) |
HURUSE Mitsuhiro 九州大学, 大学院・農学研究院, 教授 (30209176)
TAKAHASHI Kazuaki 山形県立米沢女子短期大学, 健康栄養学科, 教授 (80183440)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2009: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | 暑熱ストレス / 地球温暖化対策 / ミトコンドリア / 抗酸化飼料 / ニワトリ / 活性酸素 |
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| Research Abstract |
The objective of this study was to find a possible method to improve growth performance of broiler chickens exposed to chronic heat stress. 1)Mitochondrial ROS production for control group showed little changes during the experimental periods, whereas that for the heat-stressed group (34°C)was increased after 3, 5 and 9 d of heat exposure and returned to original levels at 14d. 2)Myoblasts isolated from the pectoralissuperficialis muscles of 0-1 day old chicks were cultured and exposed to 41°C for 6 h, resulting in increased ROS production and reduced protein content of the cells. These changes were attenuated by pretreatment ofan antioxidant, Tempol for 1 h. 3)Supplementation of glutamine and glutamate to basal diets slightly but definitely alleviated decreases in body weight gain, food intake and, and ratio of the duodenal villus height to crypt depth of heat-stressed broiler chickens. Further biochemical studies including modifications of intestinal function are required to establish a method for alleviation of the stress.
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