Clarification of new regulatory mechanisms of prolactin secretion by salsolinol and its physiological actions in ruminants
| Project/Area Number |
21380169
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Iwate University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KASUYA Etsuko (独)農業生物資源研究所, 研究員 (90355743)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2009: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Keywords | 生産機能制御 / サルソリノール / プロラクチン / ドーパミン / ヤギ / メラトニン / L-DOPA / ウシ |
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| Research Abstract |
The effects of salsolinol (SAL) on the secretion of prolactin (PRL) were examined in ruminants.SAL was able to stimulate the release of PRL not only in male and female calves, but also in adult cows. The seasonal effects on PRL-releasing response to SAL were observed in goats, and a long photo period enhanced the PRL-releasing response to SAL in goats. A dopamine agonist inhibited the SAL-induced PRL release in goats. These results show that SAL is a potent physiological PRL-releasing factor in ruminants.
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Report
(4 results)
Research Products
(35 results)
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[Presentation] In vivo characteristics of salsolinol on the secretion of prolactin in ruminants2010
Author(s)
Hashizume T., Sawada T., Yaegashi T., Saito H., Nakajima Y., Goto Y., Ezzat Ahmed A., Jin J., Sawai K., Kasuya E., Nagy, G.M
Organizer
14th International Congress of Endocrinology
Place of Presentation
Kyoto
Related Report
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[Presentation] 日長変化とSalsolinolによるヤギのプロラクチン分泌反応に関する研究2009
Author(s)
Hashizume T., Sawada T., Yaegashi T., Saito H., Ezzat Ahmed A., Goto Y., Nakajima Y., Jin J., Kasuya E., Nagy G.M八重樫朋祥,澤田建,中嶋侑佳,金金,斉藤隼人,後藤由希,Ahmed Ezzat Ahmed,澤井健,橋爪力
Organizer
第102回日本繁殖生物学会
Place of Presentation
奈良,近畿大学
Related Report
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