Functions of gicerin, a cell adhesion molecule in development, memory and oncogenesis of animals
| Project/Area Number |
21380182
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Kyoto Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Keywords | 細胞接着分子 / 発生 / 記憶 / 腫瘍 / 獣医学 |
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| Research Abstract |
In this study, the expression and functions of gicerin were examined in development, memory and oncogenesis of animals. Gicerin appeared in the skin dermal autografs of chickens and promoted the regeneration of epithelia of grafts. Furthermore, gicerin promoted the metastatic activities of tumor cells including colorectal cancer cells and marek's disease. Gicern knockout mice were totally lethal in development, thus its potential role in organogenesis and memory remains to be elucidated.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Antibodies against swine influenza virus neutralize the pandemic influenza virus A/H1N12011
Author(s)
Tsukamoto M, Hiroi S, Adachi K, Kato H, Inai M, Konishi I, Tanaka M, Yamamoto R, Sawa M, Handharyani E, Tsukamoto Y.
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Journal Title
Mol Med Rep
Volume: 4
Pages: 209-214
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