Development of New Catalytic Control Methods of Chemoselectivity Using Multinuclear Metal Clusters
| Project/Area Number |
21390003
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyushu University (2010-2011)
Osaka University (2009) |
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Principal Investigator |
OHSHIMA Takashi 九州大学, 大学院・薬学研究院, 教授 (10313123)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2009: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Keywords | 金属クラスター / 触媒 / 環境調和 / 化学選択性 / 多核亜鉛触媒反応 / 添加効果 / 触媒的不斉アルキニル化反応 / ロジウム触媒反応 / プロパルギルアルコール / 水酸基直接活性化 / 直接アミノ化反応 / マイクロ波照射 / 白金触媒反応 / 金触媒反応 |
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| Research Abstract |
We succeeded in the development of(1) practical synthetic method of Trifluoroacetic Acid Adduct of Trifluoroacetate-Bridged Tetranuclear Zinc Cluster,(2) the Zn cluster-catalyzed acetylation and deacetylation reactions,(3) acceleration of the Zn cluster-catalyzed transesterification by the addition of alkylamines or N-heterocyclic compounds,(4) Pt-catalyzed direct amination of allylic alcohols under mild conditions,(5) Au-catalyzed direct substitution of the hydroxy group with highly functionalized nitrogen nucleophiles,(6) C1-Symmetric Rh-Phebox-Catalyzed Asymmetric Alkynylation ofα-Keto Ester, and so on.
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Report
(4 results)
Research Products
(171 results)
