| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
|
|---|
| Research Abstract |
Obesity is related to the development of type 2 diabetes mellitus, hypertension, and hyperlipidemia. Obesity results from hypertrophy of individual adipocytes and hyperplasia of adipocytes. Since hyperplasia of adipocytes is caused by the formation of mature adipocytes from preadipocytes, it is important to elucidate the molecular mechanism of adipocyte differentiation. In this study, many genes including novel genes were identified and characterized. Moreover, the knockout mice for two novel genes showed that these genes function as regulators for lung development, bone formation and embryonic development, indicating that these key genes have multiple functions in development.
|
