Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2011: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2010: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
|
Research Abstract |
Fhod3, a member of formin family proteins that play pivotal roles in actin filament assembly, plays a crucial role in organization of the sarcomere(the contractile unit of myofibrils) in cultured cardiomyocytes. Indeed Fhod3-gene-deficient mice are embryonic lethal due to defective myofibrillogenesis at an early stage of heart development. Thus Fhod3 is a protein essential for cardiogenesis.
|