| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Research Abstract |
Advances in the knowledge of the stem cells ; ES, iPS or tissue-specific stem cells, have allowed the significant improvement of regenerative medicine. However, these stem cells cannot differentiate into functional mature cells without an appropriate environment. Thus, the manipulation of the environment factors is necessary for the regeneration at various tissues. In this study, we have focused on Notch ligands as an environment factor, and examine their physiological significances for the development of lymphocytes or pancreas.
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