Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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Research Abstract |
Polyaromatic hydrocarbons(PAHs) are accumulated in the environment, and humans are exposed to them via food and environmental media. The objective of the present study is to elucidate possible effects and toxicity mechanisms of gestational exposure to PAHs in mice using behavioral tests. As a result, aryl hydrocarbon receptor itself was suggested to play a responsible role in the behavioral abnormality. The possible biological significance of this receptor in the brain function warrants future studies.
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