| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Research Abstract |
(1) The human epidermal growth factor receptor genotype plays a crucial role in assessing individual susceptibility to lung cancer associated with radiation exposure.(2) The genotype NKG2D, related to NK activity, affects hepatitis C virus(HCV) clearance following HCV infection and determination of treatment course if HCV infection persists, with radiation exposure and this genotype involved in development of hepatocellular carcinoma.(3) The genotypes of DNA repair-related gene polymorphisms may contribute to inter-individual differences in susceptibility to radiation-related cancer development.(4) CD14 and IL18 genotypes might be involved in development of colon cancer among A-bomb survivors, and response to radiation might vary according to these genotypes.
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