Project/Area Number |
21390210
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Public health/Health science
|
Research Institution | Kinki University |
Principal Investigator |
IKI Masayuki 近畿大学, 医学部, 教授 (50184388)
|
Co-Investigator(Kenkyū-buntansha) |
KURUMATANI Norio 奈良県立医科大学, 医学部, 教授 (10124877)
TAMAKI Junko 近畿大学, 医学部, 准教授 (90326356)
FUJITA Yuki 近畿大学, 医学部, 助教 (10330797)
SATO Yuho 仁愛大学, 生活学部, 准教授 (10337115)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
|
Keywords | 骨粗鬆症 / 骨折 / 循環器疾患 / リスク評価 / 骨密度 / リスク要因 / コホート研究 / 骨代謝マーカー / 高齢男性 |
Research Abstract |
The present study aimed to clarity risk factors of osteoporotic fractures and the effects of fractures and coronary risk factors on mortality in a population-based cohort of 2159 elderly Japanese men. Predictors for fractures appeared to be low bone density, and those for mortality were older age, higher CRP levels and incident fractures(age-adjusted hazard ratio(HR) of fracture : 17.9, multivariate-adjusted HR : 12.9). Thus, incident clinical fractures appeared to be a potent risk factor for mortality in community-dwelling elderly Japanese men.
|