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Independent and combined effects of prevalent vertebral fracture and coronary risk factors on disability-free survival

Research Project

Project/Area Number 21390210
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionKinki University

Principal Investigator

IKI Masayuki  近畿大学, 医学部, 教授 (50184388)

Co-Investigator(Kenkyū-buntansha) KURUMATANI Norio  奈良県立医科大学, 医学部, 教授 (10124877)
TAMAKI Junko  近畿大学, 医学部, 准教授 (90326356)
FUJITA Yuki  近畿大学, 医学部, 助教 (10330797)
SATO Yuho  仁愛大学, 生活学部, 准教授 (10337115)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Keywords骨粗鬆症 / 骨折 / 循環器疾患 / リスク評価 / 骨密度 / リスク要因 / コホート研究 / 骨代謝マーカー / 高齢男性
Research Abstract

The present study aimed to clarity risk factors of osteoporotic fractures and the effects of fractures and coronary risk factors on mortality in a population-based cohort of 2159 elderly Japanese men. Predictors for fractures appeared to be low bone density, and those for mortality were older age, higher CRP levels and incident fractures(age-adjusted hazard ratio(HR) of fracture : 17.9, multivariate-adjusted HR : 12.9). Thus, incident clinical fractures appeared to be a potent risk factor for mortality in community-dwelling elderly Japanese men.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (43 results)

All 2012 2011 2010 2009

All Journal Article (19 results) (of which Peer Reviewed: 16 results) Presentation (24 results)

  • [Journal Article] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study2012

    • Author(s)
      Iki M
    • Journal Title

      Osteoporosis International

      Volume: 23 Pages: 761-770

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between vitamin K intake from fermented soybeans, natto, and bone mineral density in elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study2012

    • Author(s)
      Fujita Y
    • Journal Title

      Osteoporosis International

      Volume: 23 Pages: 705-714

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 男性の骨粗鬆症と女性の骨粗鬆症の違い2011

    • Author(s)
      伊木雅之
    • Journal Title

      Clin Calcium

      Volume: 21 Pages: 1377-83

    • Related Report
      2011 Final Research Report
  • [Journal Article] Alcohol intake and bone status in elderly Japanese men : baseline data from the FORMEN study2011

    • Author(s)
      Kouda K, Iki M, Fujita Y, Tamaki J, Yura A, Kadowaki E, Sato Y, Moon JS, Morikawa M, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Bone

      Volume: 49 Pages: 275-80

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : FORMEN Study2011

    • Author(s)
      Iki M, Tamaki J, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporos Int

      Volume: 23 Issue: 2 Pages: 761-770

    • DOI

      10.1007/s00198-011-1600-7

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 男性骨粗鬆症2011

    • Author(s)
      伊木雅之
    • Journal Title

      Current therapy

      Volume: 29(2) Pages: 8-12

    • Related Report
      2011 Final Research Report
  • [Journal Article] Association between vitamin K intake from fermented soybeans, natto, and bone mineral density in elderly Japanese men : the FORMEN study2011

    • Author(s)
      Fujita Y, Iki M, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporos Int

      Volume: 23 Issue: 2 Pages: 705-714

    • DOI

      10.1007/s00198-011-1594-1

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Alcohol intake and bone status in elderly Japanese men : baseline data from the Fujiwara-kyo osteoporosis risk in men (FORMEN) study2011

    • Author(s)
      Kouda K
    • Journal Title

      Bone

      Volume: 49 Pages: 275-280

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of smoking on bone mineral density and bone metabolism in elderlymen : the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study2011

    • Author(s)
      Tamaki J
    • Journal Title

      Osteoporosis International

      Volume: 22 Pages: 133-141

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 男性における骨粗鬆症と女性における骨粗鬆症の違い2011

    • Author(s)
      伊木雅之
    • Journal Title

      クリニカルカルシウム

      Volume: 21 Pages: 1377-1383

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Impact of smoking on bone mineral density and bone metabolism in elderly men : the Fujiwara-kyo Osteonorosis Risk in Men (FORMEN) study2011

    • Author(s)
      Tamaki J, Iki M, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporosis International

      Volume: 22 Pages: 133-141

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between Vitamin K Intake from Fermented Soybeans, Natto, and Bone Mineral Density in Elderly Japanese Men : The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study2011

    • Author(s)
      Fujita Y, Iki M, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporosis International

      Volume: 22(in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] erum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN)2011

    • Author(s)
      Iki M, Tamaki, J, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporosis International

      Volume: 22(in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of smoking on bone mineral density and bone metabolism in elderly men : The FORMEN Study2010

    • Author(s)
      Tamaki J, Iki M, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, 他4名
    • Journal Title

      Osteoporosis Int

      Volume: 22 Issue: 1 Pages: 133-141

    • DOI

      10.1007/s00198-010-1238-x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship of tooth loss to mild memory impairment and cognitive impairment : findings from the Fujiwara-kyo study2010

    • Author(s)
      Okamoto N, Morikawa M, Okamoto K, Habu N, Iwamoto J, Tomioka K, Saeki K, Yanagi M, Amano N, Kurumatani N
    • Journal Title

      Behav Brain Funct

      Volume: 6 Pages: 77-77

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tooth loss is associated with mild memory impairment in the elderly : the Fujiwara-kyo study2010

    • Author(s)
      Okamoto N, Morikawa M, Okamoto K, Habu N, Hazaki K, Harano A, Iwamoto J, Tomioka K, Saeki K, Kurumatani N
    • Journal Title

      Brain Res

      Volume: 1349 Pages: 68-75

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Increasing the number of steps walked each day improves physical fitness in Japanese community-dwelling adults2010

    • Author(s)
      Okamoto N, Nakatani T, Okamoto Y, Iwamoto J, Saeki K, Kurumatani N
    • Journal Title

      Int J Sports Med

      Volume: 31 Pages: 277-82

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Design and baseline characteristics of a prospective cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : The FORMEN Study2009

    • Author(s)
      Iki M, Fujita Y, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, et al.
    • Journal Title

      BMC Musculoskelet Disord

      Volume: 10 Pages: 165-165

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Design and baseline characteristics of a prospective cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men(FORMEN)Study2009

    • Author(s)
      Masayuki Iki, et al.
    • Journal Title

      BMC Musculoskeletal Disorders 180

      Pages: 165-165

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Epideniology of Osteoporosis in Japan2011

    • Author(s)
      Iki M
    • Organizer
      The 12th Annual Meeting of the Korean Society of Osteoporosis
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 骨粗鬆症の疫学とそれによる骨折のリスク評価2011

    • Author(s)
      伊木雅之
    • Organizer
      第13回日本骨粗鬆症学会
    • Place of Presentation
      神戸市
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 地域ベースのコホート研究から見た骨折・骨粗鬆症と糖尿病の関連2011

    • Author(s)
      伊木雅之
    • Organizer
      徳島大学糖尿病臨床・研究開発センター講演会
    • Place of Presentation
      徳島市
    • Year and Date
      2011-01-24
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] GFR estimated with serum creatinine may be misleading in association between subclinical decline in renal function and bone mass in community-dwelling elderly men : FORMEN Study2011

    • Author(s)
      Iki M, et al.
    • Organizer
      3rd Joint Meeting of ECTS & IBMS
    • Place of Presentation
      Athens, Greece
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 骨代謝における軽度・中等度腎機能低下の影響~藤原京スタディ男性骨粗鬆症コホート研究~2011

    • Author(s)
      藤田裕規、伊木雅之、玉置淳子、甲田勝康、由良晶子、門脇英子、佐藤裕保、文鐘聲、冨岡公子、岡本希、車谷典男
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Final Research Report
  • [Presentation] HMG-CoA還元酵素阻害剤は骨量低下を抑制するか-藤原京スタディ男性骨折コホート研究の断面検討2011

    • Author(s)
      玉置淳子、伊木雅之、藤田裕規、甲田勝康、由良晶子、門脇英子、佐藤裕保、文鐘聲、冨岡公子、岡本希、車谷典男
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌市
    • Related Report
      2011 Final Research Report
  • [Presentation] 骨代謝における軽度・中等度腎機能低下の影響~藤原京スタディ男性骨粗鬆症コホート研究~.2011

    • Author(s)
      藤田裕規, 他
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Annual Research Report
  • [Presentation] HMG-CoA還元酵素阻害剤は骨量低下を抑制するか-藤原京スタディ男性骨折コホート研究の断面検討2011

    • Author(s)
      玉置淳子, 他
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Annual Research Report
  • [Presentation] 習慣的牛乳飲用は男性高齢者でも高骨密度に関連する-藤原京スタディ男性骨粗鬆症研究2010

    • Author(s)
      佐藤裕保、伊木雅之、藤田裕規、玉置淳子、甲田勝康、由良晶子、門脇英子、文鐘聲、冨岡公子、岡本希、車谷典男
    • Organizer
      第69回日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 高齢者における慢性腎臓病有病状況とその循環器リスク要因への影響-藤原京スタディ-2010

    • Author(s)
      伊木雅之、玉置淳子、藤田裕規、甲田勝康、由良晶子、門脇英子、冨岡公子、岡本希、車谷典男
    • Organizer
      第69回日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] Baseline data of a cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men(FORMEN) Study2010

    • Author(s)
      Masayuki Iki, et al.
    • Organizer
      The Joint Scientific Meeting of IEA Western Pacific Region and Japan Epidemiological Association
    • Place of Presentation
      越谷市
    • Related Report
      2011 Final Research Report
  • [Presentation] SUBCLINICAL DECLINE IN RENAL FUNCTION WAS ASSOCIATED WITH INCREASED BONE DENSITY IN A JAPANESE ELDERLY MALE POPULATION : FORMEN STUDY.2010

    • Author(s)
      Iki M, et al.
    • Organizer
      The IOF World Congress on Osteoporosis and 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis
    • Place of Presentation
      Firenze
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人高齢男性では血清オステオカルシン濃度は空腹時血糖値、並びにヘモグロビンAlc値と逆相関する.藤原京スタディ男性骨粗鬆症(FORMEN)研究2010

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人高齢男性では、推定糸球体濾過量は骨密度と逆相関した-藤原京スタディ男性骨粗鬆症(FORMEN)研究2010

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      大阪
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高齢者における慢性腎臓病有病状況とその循環器リスク要因への影響-藤原京スタディ-2010

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 習慣的牛乳飲用は男性高齢者でも高骨密度に関連する-藤原京スタディ男性骨粗鬆症研究2010

    • Author(s)
      佐藤裕保, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN)2010

    • Author(s)
      Iki M, et al.
    • Organizer
      IOF Asian-Pacific Osteoporosis Meeting
    • Place of Presentation
      Singapore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Baseline data of a cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men(FORMEN)Study2010

    • Author(s)
      伊木雅之, et al.
    • Organizer
      The Joint Scientific Meeting of TEA Western Pacific Region and Japan Epidemiological Association
    • Place of Presentation
      越谷市
    • Related Report
      2009 Annual Research Report
  • [Presentation] 捨て置かれし男性の骨を守ろう!藤原京スタディ男性骨粗鬆症コホート研究の発進2009

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良市
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 納豆摂取による骨密度低下の予防効果~藤原京スタディ男性骨粗鬆症コホート研究~2009

    • Author(s)
      藤田裕規, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良市
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 禁煙は骨密度低下の速度を下げる-藤原京スタディ男性骨粗鬆症コホート研究の断面検討2009

    • Author(s)
      玉置淳子, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良市
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 適度な飲酒は骨粗鬆症を防ぐ-藤原京スタディ男性骨粗鬆症コホート研究-2009

    • Author(s)
      甲田勝康, 他
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良市
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 藤原京スタディ男性骨粗鬆症コホート研究の発進2009

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      名古屋市
    • Related Report
      2011 Final Research Report
  • [Presentation] 藤原京スタディ男性骨粗鬆症ゴホート研究の発進2009

    • Author(s)
      伊木雅之, 他
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      名古屋市
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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