|Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2009: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Elevated circulating Asymmetric Dimethylarginine(ADMA) is a cause, not an epiphenomenon, of endothelial dysfunction in chronic kidney disease. This effect is attributable to inhibition of endothelial nitric oxide synthase phosphorylation, which is independent of the competitive inhibition of nitric oxide synthase.