| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2009: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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| Research Abstract |
To investigate the mechanisms and the search of the molecular targets for lung cancer metastasis, we developed the methods for purifying the circulating tumor cells(CTC) from peripheral blood, and we created the prototype device using the nanopillar technique. We also investigated the genetic profiles of CTC, and selected the genes, which were characteristic for CTC. EMT regulatory molecules of ZEB1 and Twist will become molecular targets for lung cancer metastasis.
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