| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2009: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
|
|---|
| Research Abstract |
In this research program, the role of the candidate genes linked to the glial pathology in amyotrophic lateral sclerosis mouse model was examined. Mice deficient ofα7-nAChR gene showed slowing late disease progression in ALS mice. Moreover, ES-derived motor neuron culture and plant-derived chemical library were established as tools for investigating glial pathology in vitro.
|
