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Molecular anlysis and development of targeting therapy in pediatric solid tumors by use of whole genomic and epigenomic resolution

Research Project

Project/Area Number 21390316
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Pediatrics
Research InstitutionGunma Institute of Public Health and Environmental Sciences

Principal Investigator

HAYASHI Yasuhide  群馬県衛生環境研究所, 研究企画係, 研究員 (30238133)

Co-Investigator(Kenkyū-buntansha) SOTOMATSU Manabu  群馬県衛生環境研究所, 研究企画係, 研究員 (70251113)
PARK Myoung-ja  群馬県衛生環境研究所, 研究企画係, 研究員 (50450375)
OHKI Kentaro  群馬県衛生環境研究所, 研究企画係, 研究員 (50400966)
佐野 弘純  群馬県衛生環境研究所, 研究企画係, 研究員 (20469878)
Co-Investigator(Renkei-kenkyūsha) OGAWA Seishi  東京大学, 医学部・附属病院, 特任教授 (60292900)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2011: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2010: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords小児腫瘍学 / 遺伝子 / ゲノム / マイクロアレイ / 癌 / 臨床
Research Abstract

Partial deficient ALK was found to be involved in tumorigenesis of neuroblastoma(NB), and novel activating mutations of ALK gene were found in Ewing Sarcoma. High expression of ALK gene was found in 50 cases with rhabdomyosarcoma. Aberrations of ILD1 and 2 genes were found in 4 pediatric tumors including NB. Furthermore, exome analysis using next generation sequencer and analysis of ALK pathway-related genes revealed several new aberrations in NB, suggesting that ALK pathway plays an important role in the development and advance of neuroblastoma and could be molecular target for treatment.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (231 results)

All 2012 2011 2010 2009 Other

All Journal Article (66 results) (of which Peer Reviewed: 66 results) Presentation (164 results) Remarks (1 results)

  • [Journal Article] Aberrant activation of ALK kinase by a novel truncated form ALK protein in neuroblastoma2012

    • Author(s)
      Okubo J, Takita J, Chen Y, Oki K, Nishimura R, Kato M, Sanada M, Hiwatari M, Hayashi Y, Igarashi T, Ogawa S.
    • Journal Title

      Oncogene

      Volume: 31 Issue: 44 Pages: 4667

    • DOI

      10.1038/onc.2011.616

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse : a study of the Japanese Childhood AML Cooperative Study Group2012

    • Author(s)
      Sano H, Shimada A, Taki T, Murata C, Park MJ, Sotomatsu M, Tabuchi K, Tawa A, Kobayashi R, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y.
    • Journal Title

      Int J Hematol

      Volume: 95 Issue: 5 Pages: 509-515

    • DOI

      10.1007/s12185-012-1033-x

    • NAID

      10030633077

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia2012

    • Author(s)
      Yokoyama T, Toki T, Aoki Y, Kanezaki R, Park MJ, Kanno Y, Takahara T, Yamazaki Y, Ito E, Hayashi Y, Nakamura T.
    • Journal Title

      Blood

      Volume: 119 Issue: 11 Pages: 2608-2611

    • DOI

      10.1182/blood-2010-12-324806

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia2012

    • Author(s)
      Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y.
    • Journal Title

      Blood

      Volume: 119 Issue: 11 Pages: 2612-2614

    • DOI

      10.1182/blood-2011-02-333435

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical significance of early T-cell precursor acute lymphoblastic leukaemia : Results of the Tokyo Children's Cancer Study Group Study L99-152012

    • Author(s)
      Inukai T, Kiyokawa N, Campana D, Coustan-Smith E, Kikuchi A, Kobayashi M, Takahashi H, Koh K, Manabe A, Kumagai M, Ikuta K, Hayashi Y, Tsuchida M, Sugita K, Ohara A.
    • Journal Title

      Brit J Haematol

      Volume: 156 Issue: 3 Pages: 358-365

    • DOI

      10.1111/j.1365-2141.2011.08955.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia2012

    • Author(s)
      Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y.
    • Journal Title

      Br J Haematol

      Volume: 156 Issue: 3 Pages: 413-414

    • DOI

      10.1111/j.1365-2141.2011.08879.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutations in infant acute lymphoblastic leukaemia2012

    • Author(s)
      6. Shiba N, Park MJ, Taki T, Takita J, Hiwatari M, Kanazawa T, Sotomatsu M, Ishii E, Arakawa H, Ogawa S, Hayashi Y
    • Journal Title

      Br J Haematol

      Volume: 156 Issue: 5 Pages: 672

    • DOI

      10.1111/j.1365-2141.2011.08900.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Aberrations of NEGR1 on 1p31 and MYEOV on 11q13 in neuroblastoma2011

    • Author(s)
      Takita J, Chen Y, Okubo J, et al
    • Journal Title

      Canser Science

      Volume: 102 Issue: 9 Pages: 1645-1650

    • DOI

      10.1111/j.1349-7006.2011.01995.x

    • NAID

      10030242926

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutation in childhood therapy-related leukemia2011

    • Author(s)
      Shiba N, Taki T, Park MJ, Nagasawa M, Kanazawa T, Takita J, Ohnishi H, Sotomatsu M, Arakawa H, Hayashi Y.
    • Journal Title

      Leukemia

      Volume: 25 Issue: 8 Pages: 1356-1358

    • DOI

      10.1038/leu.2011.75

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chromosome abnormalities in advanced stage T-cell lymphoblastic lymphoma of children and adolescents : a report from Japanese Paediatric Leukaemia/Lymphoma Study Group(JPLSG) and review of the literature2011

    • Author(s)
      Sekimizu M, Sunami S, Nakazawa A, Hayashi Y, Okimoto Y, Saito AM, Horibe K, Tsurusawa M, Mori T.
    • Journal Title

      Br J Haematol

      Volume: 154 Issue: 5 Pages: 612-617

    • DOI

      10.1111/j.1365-2141.2011.08788.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies2011

    • Author(s)
      Oki K, Takita J, Hiwatari M, Nishimura R, Sanada M, Okubo J, Adachi M, Sotomatsu M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Journal Title

      Leukemia

      Volume: 25 Issue: 2 Pages: 382

    • DOI

      10.1038/leu.2010.307

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oncogenic mutations of ALK in neuroblastoma2011

    • Author(s)
      Ogawa S, Takita J, Sanada M, Hayashi Y.
    • Journal Title

      Cancer Science

      Volume: 102 Issue: 2 Pages: 302-308

    • DOI

      10.1111/j.1349-7006.2010.01825.x

    • NAID

      10029289653

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Different cytokine profile and eosinophil activation are involved in rhinovirus-and RS virus-induced acute exacerbation of childhood wheezing2011

    • Author(s)
      Kato M, et al
    • Journal Title

      Pediatr Allergy Immunol

      Volume: 22 Issue: 1pt2

    • DOI

      10.1111/j.1399-3038.2010.01026.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential effects of corticosteroids on serum eosinophil cationic protein and cytokine production in rhinovirus- and respiratory syncytial virus-induced acute exacerbation of childhood asthma2011

    • Author(s)
      Kato M, et al
    • Journal Title

      Int Arch Allergy Immunol

      Volume: 155Suppl1 Issue: Suppl. 1 Pages: 77-84

    • DOI

      10.1159/000327434

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eosinophilic gastrointestinal disorders in infants : a Japanese case series2011

    • Author(s)
      Yamada Y, et al
    • Journal Title

      Int Arch Allergy Immunol

      Volume: 155Suppl1 Issue: Suppl. 1 Pages: 40-45

    • DOI

      10.1159/000327264

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies.2011

    • Author(s)
      Oki K, et al.
    • Journal Title

      Leukemia

      Volume: 25 Pages: 382-384

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oncogenic mutations of ALK in neuroblastoma.2011

    • Author(s)
      Ogawa S, et al.
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 302-308

    • NAID

      10029289653

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FLT3-internal tandem duplication, CD56 expression, and obstructive jaundice due to granulocytic sarcoma at relapse in a pediatric patient with t(8 ; 21) acute myeloid leukemia2010

    • Author(s)
      Kawamura M, Kaku H, Ito T, Funata N, Taki T, Shimada A, Hayashi Y.
    • Journal Title

      Cancer Genet Cytogenet

      Volume: 203 Pages: 292-296

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prominent eosinophilia but less eosinophil activation in a patient with Omenn syndrome2010

    • Author(s)
      Seki M, Kimura H, Mori A, Shimada A, Yamada Y, Maruyama K, Hayashi Y, Agematsu K, Morio T, Yachie A, Kato M.
    • Journal Title

      Pediatr Int

      Volume: 52 Issue: 4 Pages: 96-9

    • DOI

      10.1111/j.1442-200x.2010.03135.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] High frequencies of simultaneous FLT3-ITD, WT1, and KIT mutations in hematologic malignancies with NUP98-fusion genes2010

    • Author(s)
      Taketani T, Taki T, Nakamura T, Kobayashi K, Ito E, Fukuda S, Yamaguchi S, Hayashi Y
    • Journal Title

      Leukemia

      Volume: 24 Issue: 11 Pages: 1975-1977

    • DOI

      10.1038/leu.2010.207

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia2010

    • Author(s)
      Shiba N, Kanazawa T, Park MJ, Okuno H, Tamura K, Tsukada S, Hayashi Y, Arakawa H.
    • Journal Title

      Pediatr Blood Cancer

      Volume: 55 Issue: 7 Pages: 1406-1409

    • DOI

      10.1002/pbc.22758

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder : mutation classes correlate with progression to myeloid leukemia2010

    • Author(s)
      Kanezaki R, Toki T, Terui K, Xu G, Wang R, Shimada A, Hama A, Kanegane H, Kawakami K, Endo M, Hasegawa D, Kogawa K, Adachi S, Ikeda Y, Iwamoto S, Taga T, Kosaka Y, Kojima S, Hayashi Y, Ito E.
    • Journal Title

      Blood

      Volume: 116 Issue: 22 Pages: 4631-4638

    • DOI

      10.1182/blood-2010-05-282426

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Expression of ADAMTS4 in Ewing's sarcoma2010

    • Author(s)
      Minobe K, Ono R, Matsumine A, Shibata-Minoshima F, Izawa K, Oki T, Kitaura J, Iino T, Takita J, Iwamoto S, Hori H, Komada Y, Uchida A, Hayashi Y, Kitamura T, Nosaka T.
    • Journal Title

      Int J Oncol

      Volume: 37 Issue: 3 Pages: 569-581

    • DOI

      10.3892/ijo_00000706

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype : a study by the Japanese Childhood AML Cooperative Study Group2010

    • Author(s)
      Mizushima Y, Taki T, Shimada A, Yui Y, Hiraumi Y, Matsubara H, Watanabe M, Watanabe K, Kamitsuji Y, Hayashi Y, Tsukimoto I, Kobayashi R, Horibe K, Tawa A, Nakahata T, Adachi S.
    • Journal Title

      Int J Hematol

      Volume: 91 Issue: 5 Pages: 831-837

    • DOI

      10.1007/s12185-010-0585-x

    • NAID

      10026511260

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model2010

    • Author(s)
      Komeno Y, Kitaura J, Watanabe-Okochi N, Kato N, Oki T, Nakahara F, Harada Y, Harada H, Shinkura R, Nagaoka H, Hayashi Y, Honjo T, Kitamura T.
    • Journal Title

      Leukemia

      Volume: 24 Issue: 5 Pages: 1018-1024

    • DOI

      10.1038/leu.2010.40

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tokyo Children's Cancer Study Group. Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia2010

    • Author(s)
      Tsuchida M, Ohara A, Manabe A, Kumagai M, Shimada H, Kikuchi A, Mori T, Saito M, Akiyama M, Fukushima T, Koike K, Shiobara M, Ogawa C, Kanazawa T, Noguchi Y, Oota S, Okimoto Y, Yabe H, Kajiwara M, Tomizawa D, Ko K, Sugita K, Kaneko T, Maeda M, Inukai T, Goto H, Takahashi H, Isoyama K, Hayashi Y, Hosoya R, Hanada R
    • Journal Title

      Leukemia

      Volume: 24 Issue: 2 Pages: 383-396

    • DOI

      10.1038/leu.2009.260

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome2010

    • Author(s)
      Shiba N, Kato M, Park MJ, Sanada M, Ito E, Fukushima K, Sako M, Arakawa H, Ogawa S, Hayashi Y.
    • Journal Title

      Leukemia

      Volume: 24 Issue: 5 Pages: 1090-1092

    • DOI

      10.1038/leu.2010.49

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome.2010

    • Author(s)
      Shiba N, et al.
    • Journal Title

      Leukemia

      Volume: 24 Pages: 1090-1092

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative assessment of PTPN11 or RAS mutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia2010

    • Author(s)
      Matsuda K, et al.
    • Journal Title

      Bri J Haematol

      Volume: 148 Pages: 593-599

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype : a study by the Japanese Childhood AML Cooperative Study Group.2010

    • Author(s)
      Mizushima Y, et al.
    • Journal Title

      Int J Hematol

      Volume: 91 Pages: 831-837

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder : mutation classes correlate with progression to myeloid leukemia.2010

    • Author(s)
      Kanezaki R, et al.
    • Journal Title

      Blood

      Volume: 116 Pages: 4631-4638

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FLT3-internal tandem duplication, CD56 expression, and obstructive jaundice due to granulocytic sarcoma at relapse in a pediatric patient with t(8;21) acute myeloid leukemia.2010

    • Author(s)
      Kawamura M, et al.
    • Journal Title

      Cancer Genet Cytogenet

      Volume: 203 Pages: 292-296

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes.2010

    • Author(s)
      Taketani T, et al.
    • Journal Title

      Leukemia

      Volume: 24 Pages: 1975-1977

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia.2010

    • Author(s)
      Shiba N, et al.
    • Journal Title

      Pediatr Blood Cancer

      Volume: 55 Pages: 1406-1409

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of ADAMTS4 in Ewing's sarcoma.2010

    • Author(s)
      Minobe K, et al.
    • Journal Title

      Int J Oncol

      Volume: 37 Pages: 569-581

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.2010

    • Author(s)
      Komeno Y, et al.
    • Journal Title

      Leukemia

      Volume: 24 Pages: 1018-1024

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999.2010

    • Author(s)
      Tsuchida M, et al.
    • Journal Title

      Leukemia

      Volume: 24 Pages: 383-396

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 初診時にコンパートメント症候群を合併した血友病Aの1乳児例2010

    • Author(s)
      外松学, 他
    • Journal Title

      日本小児血液学会雑誌

      Volume: 24 Pages: 111-114

    • NAID

      10026419422

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 神経芽腫におけるreceptor tyrosine kinase(RTK)および癌抑制遺伝子DCCの発現と臨床的予後因子との相関について2010

    • Author(s)
      佐野弘純, 他
    • Journal Title

      小児がん

      Volume: 47 Pages: 424-427

    • NAID

      110008661024

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 典型例とは異なる緩徐な臨床経過を示し、リボソームタンパク遺伝子RPLI1の変異の検出により診断したDiamond-Blackfan貧血の1例2010

    • Author(s)
      佐野弘純, 他
    • Journal Title

      日本小児血液学会雑誌

      Volume: 24 Pages: 225-228

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Long-term results of Tokyo Children's Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999.2010

    • Author(s)
      Tsuchida M, et al.
    • Journal Title

      Leukemia 24

      Pages: 383-396

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mixed-lineage-leukemia(MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation2009

    • Author(s)
      Ono R, Kumagai H, Nakajima H, Hishiya A, Taki T, Horikawa K, Takatsu K, Satoh T, Hayashi Y, Kitamura T, Nosaka T.
    • Journal Title

      Leukemia

      Volume: 23 Issue: 12 Pages: 2197-2209

    • DOI

      10.1038/leu.2009.177

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome2009

    • Author(s)
      Kuroiwa M, Sakamoto J, Shimada A, Suzuki N, Hirato J, Park MJ, Sotomatsu M, Hayashi Y.
    • Journal Title

      J Pediatr Surg

      Volume: 44 Issue: 3 Pages: 31-35

    • DOI

      10.1016/j.jpedsurg.2008.12.010

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] JAK2V617F mutation-positive childhood essential thrombocythemia associated with cerebral venous sinus thrombosis2009

    • Author(s)
      Kurosawa H, Okuya M, Matsushita T, Kubota T, Endoh K, Kuwashima S, Hagisawa S, Sato Y, Fukushima K, Sugita K, Okada Y, Park MJ, Hayashi Y, Arisaka O.
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 31 Issue: 9 Pages: 678-680

    • DOI

      10.1097/mph.0b013e3181b1ec9e

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
    • Journal Title

      Nature

      Volume: 460 Issue: 7257 Pages: 904-908

    • DOI

      10.1038/nature08240

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene2009

    • Author(s)
      Takita J, Motomura A, Koh K, Ida K, TakiT, Hayashi Y, Igarashi T.
    • Journal Title

      Eur J Haematol

      Volume: 83 Issue: 2 Pages: 149

    • DOI

      10.1111/j.1600-0609.2009.01275.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Frequent inactivation of A20 in B-cell lymphomas2009

    • Author(s)
      Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Niwa A, Chen Y, Nakazaki K, Nomoto J, Asakura Y, Muto S, Tamura A, Iio M, Akatsuka Y, Hayashi Y, Mori H, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S.
    • Journal Title

      Nature

      Volume: 459 Issue: 7247 Pages: 712-716

    • DOI

      10.1038/nature07969

    • NAID

      40019064821

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8 ; 11)(p11 ; p15) and expression pattern of NSD family genes2009

    • Author(s)
      Taketani T, Taki T, Nakamura H, Taniwaki M, Masuda J, Hayashi Y.
    • Journal Title

      Cancer Genet Cytogenet

      Volume: 190 Issue: 2 Pages: 108-112

    • DOI

      10.1016/j.cancergencyto.2008.12.008

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis2009

    • Author(s)
      Watanabe-Okochi N, Oki T, Komeno Y, Kato N, Yuji K, Ono R, Harada Y, Harada H, Hayashi Y, Nakajima H, Nosaka T, Kitaura J, Kitamura T.
    • Journal Title

      Int J Hematol

      Volume: 89 Issue: 4 Pages: 470-481

    • DOI

      10.1007/s12185-009-0299-0

    • NAID

      10025161257

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Juvenile myelomonocytic leukemia with t(7 ; 11)(p15 ; p15) and NUP98-HOXA11 fusion2009

    • Author(s)
      Mizoguchi Y, Fujita N, Taki T, Hayashi Y, Hamamoto K.
    • Journal Title

      Am J Hematol

      Volume: 84 Issue: 5 Pages: 295-297

    • DOI

      10.1002/ajh.21373

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma2009

    • Author(s)
      Park MJ, Taki T, Oda M, Watanabe T, Yumura-Yagi K, Kobayashi R, Suzuki N, Hara J, Horibe K, Hayashi Y.
    • Journal Title

      Brit J Haematol

      Volume: 145 Issue: 2 Pages: 198-206

    • DOI

      10.1111/j.1365-2141.2009.07607.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Age-associated difference in gene expression of pediatric acute myelomonocytic lineage leukemia(FAB M4 and M5 subtypes) and its correlation with prognosis2009

    • Author(s)
      Jo A, Tsukimoto I, Ishii E, Asou N, Mitani S, Shimada A, Igarashi T, Hayashi Y, Ichikawa H.
    • Journal Title

      Brit J Haematology

      Volume: 144 Issue: 6 Pages: 917-929

    • DOI

      10.1111/j.1365-2141.2008.07531.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transient abnormal myelopoiesis in a Down syndrome newbornfollowed by acute myeloid leukemia : identification of the same chromosomal abnormality in both stages2009

    • Author(s)
      Kitoh T, Taki T, Hayashi Y, Nakamura K, Irino T, Osaka M.
    • Journal Title

      Cancer Genet Cytogenet

      Volume: 188 Issue: 2 Pages: 99-102

    • DOI

      10.1016/j.cancergencyto.2008.08.011

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acuteleukemia through aberrant Hox expression and Raf activation.2009

    • Author(s)
      Ono R, et al.
    • Journal Title

      Leukemia 23

      Pages: 2197-2209

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome.2009

    • Author(s)
      Kuroiwa M, et al.
    • Journal Title

      J Pediatr Surg 44

      Pages: 31-35

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] JAK2V617F mutation-positive childhood essential thrombocythemia associated with cerebral venous sinus thrombosis.2009

    • Author(s)
      Kurosawa H, et al.
    • Journal Title

      J Pediatr Hematol Oncol. 31

      Pages: 678-680

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, et al.
    • Journal Title

      Nature 460

      Pages: 904-908

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene.2009

    • Author(s)
      Takita J, et al.
    • Journal Title

      Eur J Haematol. 83

      Pages: 149-153

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Frequent inactivation of A20 in B-cell lymphomas.2009

    • Author(s)
      Kato M, et al.
    • Journal Title

      Nature. 459

      Pages: 712-716

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8 ; 11)(p11 ; p15) and expression pattern of NSD family genes.2009

    • Author(s)
      Taketani T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 190

      Pages: 108-112

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible involvement of RasGRP4 in leukemogenesis.2009

    • Author(s)
      Watanabe-Okochi N, et al.
    • Journal Title

      Int J Hematol. 89

      Pages: 470-481

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Juvenile myelomonocytic leukemia with t(7 ; 11)(p15 ; p15) and NUP98-HOXA11 fusion.2009

    • Author(s)
      Mizoguchi Y, et al.
    • Journal Title

      Am J Hematol. 84

      Pages: 295-297

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma.2009

    • Author(s)
      Park MJ, et al.
    • Journal Title

      Brit J Haematol. 145

      Pages: 198-206

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-associated difference in gene expression of pediatric acute myelomonocytic lineage leukemia (FAB M4 and M5 subtypes) and its correlation with prognosis.2009

    • Author(s)
      Jo A, et al.
    • Journal Title

      Brit J Haematology 144

      Pages: 917-929

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient abnormal myelopoiesis in a Down syndrome newborn followed by acute myeloid leukemia : identification of the same chromosomal abnormality in both stages.2009

    • Author(s)
      Kitoh T, et al.
    • Journal Title

      Cancer Genet Cytogenet. 188

      Pages: 99-102

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CBL mutation in childhood therapy-related .leukemia.

    • Author(s)
      Shiba N, et al.
    • Journal Title

      Leukemia

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 再発後にMLL-AF4陽性となったB前駆型急性リンパ性白血病の1例2012

    • Author(s)
      大木健太郎,朴明子,外松学,林泰秀
    • Organizer
      日本血液学会第167回例会
    • Place of Presentation
      東京
    • Year and Date
      2012-03-03
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] TCCSG小児B前駆細胞型急性リンパ性白血病におけるCRLF2とIKZF1の解析2011

    • Author(s)
      大木健太郎,大喜多肇,小林健一郎,清河信敬,朴明子,新井心,外松学,柴徳生,福島敬,康勝好,花田良二,真部淳,菊地陽,小原明,土田昌宏,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ダウン症候群関連ALLの発症におけるJAK2、およびCRLF2遺伝子異常の解析2011

    • Author(s)
      花田勇,照井君典,土岐力,工藤耕,佐藤知彦,神尾卓哉,佐々木伸也,高橋良博,林泰秀,杉田完爾,小島勢二,小池健一,小阪嘉之,小林正夫,伊藤悦朗
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Gene expression profiles of early T-cell precursor(ETP-) ALL and T-ALL treated in TCCSG trials2011

    • Author(s)
      清河信敬,林泰秀,小原明
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児ALL関連キメラ遺伝子発現量の抹消血中推移と既知リスク因子との関連について2011

    • Author(s)
      福島敬,南木融,清河信敬,小林千恵,福島紘子, Mahmoud Shaza,康勝好,菊地陽,真部淳,熊谷昌明,土田昌宏,林泰秀,小原明
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児固形腫瘍組織におけるI型インスリン様増殖因子受容体(IGF-1R)2011

    • Author(s)
      若井公子,大木健太郎,朴明子,外松学,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] t(9 ; 17)(p24 ; q23)を伴うJAK2遺伝子関連急性リンパ性白血病の遺伝子解析2011

    • Author(s)
      川村眞智子,賀来秀文,小野敏明,田渕健,荒木聡,滝智彦,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 再発後にMLL-AF4陽性となったBCP-ALLの一例2011

    • Author(s)
      奥野はるな、金澤崇,柴徳生,朴明子,外松学,神谷尚宏,小川千登世,林泰秀,荒川浩一
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児固形腫瘍におけるIDH 1/2変異の解析2011

    • Author(s)
      大久保淳,大木健太郎,滝田順子,樋渡光輝,西村力,真田昌,佐藤香織,五十嵐香織,林泰秀,曽我朋義,小川誠司,五十嵐隆
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Final Research Report
  • [Presentation] ASPL-TFE3キメラ遺伝子にて診断確定を得た膣原発alveolar soft part sarcomaの一例2011

    • Author(s)
      新井心,朴明子,大木健太郎,外松学,土岐文彰,山本英輝,西明,鈴木則夫,畠山信逸,中村和人,平戸純子,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 小児固形腫瘍組織におけるI型インスリン洋増殖因子受容体(IGF-1R)2011

    • Author(s)
      若井公子, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるIDH1/2変異の解析2011

    • Author(s)
      大久保淳, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 次世代シークエンサによる神経芽腫のエクソーム解析2011

    • Author(s)
      西村力,滝田順子,吉田健一,白石友一,川幡亮一郎,永田安伸,大久保淳,真田昌,林泰秀,五十嵐隆,宮野悟,小川誠司
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-26
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Gene expression profiles of early T-cell precursor (ETP-) ALL and T-ALL treated in TCCSG trials2011

    • Author(s)
      清河信敬, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] t(9;17)(p24;q23)を伴うJAK2遺伝子関連急性リンパ性白血病の遺伝子解析2011

    • Author(s)
      川村眞智子, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 小児急性白血病におけるDNMT3A遺伝子変異の解析2011

    • Author(s)
      柴徳生,朴明子,村田知里,嶋田明,滝智彦,外松学,田渕健,足立壮一,多和昭雄,堀部敬三,土田昌宏,花田良二,月本一郎,荒川浩一,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 小児急性骨髄性白血病におけるNUP98-NSD転座の解析2011

    • Author(s)
      柴徳生,朴明子,村田知里,嶋田明,滝智彦,外松学,田渕健,足立壮一,多和昭雄,堀部敬三,土田昌宏,花田良二,月本一郎,荒川浩一,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 染色体11p15異常を有する造血器腫瘍における遺伝子変異と臨床像の関連2011

    • Author(s)
      竹谷健,滝智彦,日向瑞貴,安部真理子,福田誠司,山口清次,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 東京小児がんグループ(TCCSG) ALL治療研究登録症例の網羅的遺伝子発現解析2011

    • Author(s)
      飯島一智,清河信敬,小林健一郎,大喜多肇,山田浩之,三春昌嗣,森鉄也,福島敬,南木融,斎藤正博,康勝好,真部淳,菊地陽,熊谷昌明,藤本純一郎,林泰秀,土田昌宏,小原明
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Final Research Report
  • [Presentation] TCCSG ALL登録症例の細胞抗原とキメラ遺伝子との関連性についての検討2011

    • Author(s)
      小林健一郎,福島敬,南木融,清河信敬,三春昌嗣,山田浩之,飯島一智,大喜多肇,森鉄也,熊谷昌明,藤本純一郎,斎藤正博,康勝好,真部淳,菊地陽,林泰秀,土田昌宏,小原明
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Final Research Report
  • [Presentation] T細胞型小児急性リンパ性白血病における遺伝子異常の解析2011

    • Author(s)
      朴明子,清河信敬,小田慈,真部淳,原純一,小原明,花田良二,土田昌宏,小川誠司,堀部敬三,林泰秀
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] MLL再構成陽性の小児急性リンパ性白血病のエクソーム解析2011

    • Author(s)
      堤修一,王凌華,朴明子,照井君典,佐々木伸也,伊藤悦朗,林泰秀,油谷浩幸
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 乳児白血病におけるIDH1およびIDH2遺伝子の解析2011

    • Author(s)
      樋渡光輝,大木健太郎,滝田順子,西村力,真田昌,大久保淳,外松学,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ダウン症候群に合併した一過性骨髄増殖症(TAM)および急性巨核芽球性白血病(AMKL)の全エクソンシーケンス2011

    • Author(s)
      吉田健一,土岐力,朴明子,永田安伸,王汝南,白石友一,真田昌,昆彩菜,佐藤亜依子,長崎正朗,宮野悟,金兼弘和,川上清,加藤剛二,小島勢二,林泰秀,伊藤悦朗,小川誠司
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 乳児AMLの後方視的解析2011

    • Author(s)
      嶋田明, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 東京小児がんグループ(TCCSG)ALL治療研究登録症例の網羅的遺伝子発現解析2011

    • Author(s)
      飯島一智, 他
    • Organizer
      第53回日本小児血液・がん学会学術集会
    • Place of Presentation
      前橋
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] CBL mutation in CMML secondary to familial platelet disorder with propensity to develop AML2011

    • Author(s)
      Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Clinical significance of ETP-ALL in childhood T-ALL ; the TCCSG L99-15 study2011

    • Author(s)
      Inukai T, Kiyokawa N, Ohara A, Takahashi H, Koh K, Manabe A, Kumagai M, Ikuta K, Hayashi Y, Tsuchida M, Campana D, Sugita K.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Molecular characteristics of early T-cell precursor(ETP) ALL and T-ALL treated in TCCSG trials2011

    • Author(s)
      Kiyokawa N, Iijima K, Inukai T, Takahashi H, Fukushima T, Koh Y, Sugita K, Manabe A, Kikuchi A, Kumagai M, Ohara A, Fujimoto J, Hayashi Y.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Novel GATA1 mutants with internal deletions in transient abnormal myelopoiesis in down syndrome2011

    • Author(s)
      Toki T, Kobayashi E, Kanezaki R, Wang R, Terui K, Kanegane H, Maeda M, Koike T, Endo M, Adachi S, Hayashi Y, Shimizu R, Yamamoto M, Ito E.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Whole exome analysis of transient abnormal myelopoiesis and acute megakaryocytic leukemia with Down syndrome2011

    • Author(s)
      Yoshida K, Toki T, Park MJ, Nagata Y, Wang R, Shiraishi Y, Sanada M, Nagasaki M, Miyano S, kanegane H, Kawakami K, Kato K, Hayashi Y, Ito E, Ogawa S.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Aberrations of DNMT3A in pediatric myeloid malignancies2011

    • Author(s)
      Motomura A, Oki K, Takita J, Nishimura R, Okubo J, Hiwatari M, Sanada M, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Final Research Report
  • [Presentation] The clinical significance of LEF1 mutation in childhood acute lymphblastic leukemia2011

    • Author(s)
      Park MJ, Kiyokawa N, Oda M, Manabe A, Hara J, Ohara A, Hanada R, Tsuchida M, Ogawa S, Horibe K, Hayashi Y.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Molecular characteristics of early T-cell precursor (ETP) ALL and T-ALL treated in TCCSG trials2011

    • Author(s)
      Kiyokawa N, et al
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Mutation analysis for IDH1 and IDH2 in infantile leukemia2011

    • Author(s)
      Hiwatari M, Ohki K, Takita J, Nishimura R, Sanada M, Okubo J, Sotomatsu M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 次世代シーケンサーによる神経芽腫のエクソーム解析2011

    • Author(s)
      西村力,滝田順子,吉田健一,白石友一,川幡亮一郎,永田安伸,大久保淳,真田昌,五十嵐隆,林泰秀,宮野悟,小川誠司
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 小児T細胞性急性リンパ性白血病におけるLEF1遺伝子の異常と臨床像について2011

    • Author(s)
      朴明子,清河信敬,小田慈,真部淳,小原明,花田良二,土田昌宏,小川誠司,堀部敬三,林泰秀
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 小児固形腫瘍におけるIDH変異の解析2011

    • Author(s)
      大久保淳,大木健太郎,滝田順子,樋渡光輝,西村力,真田昌,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 乳児白血病におけるIDH 1/2遺伝子の変異解析2011

    • Author(s)
      樋渡光輝,滝田順子,真田昌,西村力,大久保淳,井田孔明,外松学,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Related Report
      2011 Final Research Report
  • [Presentation] MLL関連キメラが検出されないCD10陰性ALLのマーカーと発現遺伝子の特徴2011

    • Author(s)
      清河信敬,飯島一智,加藤元博,福島敬,康勝好,真部淳,菊地陽,熊谷昌明,藤本純一郎,林泰秀,小原明
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Related Report
      2011 Final Research Report
  • [Presentation] 神経芽腫における部分欠損型ALKの造腫瘍性に関する検討2011

    • Author(s)
      大久保淳,滝田順子,大木健太郎,西村明,安達正時,加藤元博,真田昌,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 高密度SNPアレイを用いた胸膜肺芽腫における網羅的ゲノム解析2011

    • Author(s)
      大久保淳,滝田順子,大木健太郎,西村力,安達正時,真田昌,加藤啓輔,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-14
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 小児悪性腫瘍におけるIsocitrate dehydrogenase 1/2の変異解析2011

    • Author(s)
      大木健太郎,滝田順子,樋渡光輝,西村力,大久保淳,安達正時,外松学,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 治療関連白血病と乳児白血病におけるCBL遺伝子変異の解析2011

    • Author(s)
      柴徳生,滝智彦,朴明子,加藤元博,滝田順子,金澤崇,外松学,長澤正之,荒川浩一,林泰秀
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-13
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] TCCSG登録例における小児ALL関連キメラ遺伝子発現量の推移について2011

    • Author(s)
      福島敬,南木融,清河信敬,康勝好,真部淳,菊地陽,熊谷昌明,林泰秀,土田昌宏,小原明
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 10カラーフローサイトメトリー解析による小児白血病のマーカー診断2011

    • Author(s)
      清河信敬,山田浩之,康勝好,福島敬,真部淳,菊地陽,熊谷昌明,小原明,林泰秀,土田昌宏
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 革新的ゲノム解析技術を用いた難治性小児固形腫瘍における発症分子機構の解明2011

    • Author(s)
      滝田順子,西村力,安達正時,大木健太郎,大久保淳,樋渡光輝,真田昌,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 神経芽腫における全エクソン領域のシークエンス解析2011

    • Author(s)
      安達正時,滝田順子,西村力,真田昌,樋渡光輝,大木健太郎,大久保淳,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] TAMにおける遺伝学的基盤探索2011

    • Author(s)
      小川誠司,加藤元博,林泰秀
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] ダウン症候群に合併した一過性骨髄異常増殖症153例の後方視的解析2011

    • Author(s)
      村松秀城, 他
    • Organizer
      第114回日本小児科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 次世代シークエンサーによる神経芽腫におけるエクソーム解析2011

    • Author(s)
      滝田順子,安達正時,西村力,吉田健一,小川誠司,林泰秀
    • Organizer
      第6回JNBSG研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-30
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] NUP98-NSD1 fusion gene is strongly associated with a poor prognosis in pediatric acute myeloid leukemia : a study of the Japanese Childhood AML99 Cooperative Study Group2011

    • Author(s)
      Shiba N, Taki T, Park M, Murata C, Oki K, Ichikawa H, Shimada A, Kanazawa T, Sotomatsu M, Tabuchi K, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y.
    • Organizer
      53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] The Concurrent mutations in hematological malignancies with NUP98-fusion genes are associated with clinical prognosis2011

    • Author(s)
      Taketani T, Taki T, Fukuda S, Hyuga M, Onishi C, Yamaguchi S, Hayashi Y.
    • Organizer
      53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] JAK2 mutations and CRLF2 rearrangements in down syndrome associated acute lymphoblastic leukemia in Japan2011

    • Author(s)
      Hanada I, Terui K, Toki T, Kudo K, Sato T, Kamio T, Sasaki S, Takahashi Y, Hayashi Y, Sugita K, Kojima S, Koike K, Kosaka Y, Kobayashi M, Ito E.
    • Organizer
      53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Heterogeneity in infants with acute myeloid leukemia : retrospective analysis of a Japanese nationwide survey2011

    • Author(s)
      Shimada A, Tomizawa D, Kinoshita A, Hamamoto K, Tsukimoto I, Ogawa A, Taga T, Imamura T, Tawa A, Horibe K, Taki T, Hayashi Y, Adachi S.
    • Organizer
      53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] GATA1 mutants lacking Rb-binding motif observed in transient abnormal myelopoiesis in down syndrome2011

    • Author(s)
      Toki T, Kobayashi E, Kanezaki R, Wang RN, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adach S, Hayashi Y, Shimizu R, Yamamoto M, Ito E.
    • Organizer
      53rd Annual Meeting of the American Society of Hematology
    • Place of Presentation
      San Diego
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] T細胞性急性リンパ性白血病におけるLEF1遺伝子異常の解析2010

    • Author(s)
      朴明子,清河信敬,加藤元博,鈴木信寛,小田慈,原純一,小林良二,小川誠司,堀部敬三,林泰秀
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-19
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 急性骨髄性白血病におけるRAS遺伝子変異と臨床像2010

    • Author(s)
      佐野弘純,嶋田明,村田知里,朴明子,外松学,滝智彦,田渕健,多和昭雄,堀部敬三,土田昌宏,花田良二,月本一郎,林泰秀
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 治療関連白血病におけるCBLとRAS遺伝子の解析2010

    • Author(s)
      柴徳生,滝智彦,朴明子,長澤正之,金澤崇,外松学,荒川浩一,林泰秀
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 次世代シークエンサーを用いたエクソンシークエンスによる神経芽腫の標的分子の解析2010

    • Author(s)
      吉田健一,滝田順子,西村力,安達正時,大木健太郎,大久保淳,永田安伸,真田昌,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるNOTCHシグナルの検討;発現様式と遺伝子変異の解析2010

    • Author(s)
      安達正時,滝田順子,樋渡光輝,西村力,大木健太郎,大久保淳,内坂直樹,真田昌,小川誠司,林泰秀,五十嵐隆
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児悪性腫瘍におけるIsocitrate depydrogenase 1/2の変異解析2010

    • Author(s)
      大木健太郎,滝田順子,樋渡光輝,西村力,大久保淳,安達正時,真田昌,外松学,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-18
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の解析2010

    • Author(s)
      西村力,滝田順子,大木健太郎,金兼弘和,大喜多肇,藤本純一郎,陳玉彦,真田昌,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-17
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いた胸膜肺芽腫における網羅的ゲノム解析2010

    • Author(s)
      大久保淳,滝田順子,大木健太郎,西村力,内坂直樹,安達正時,真田昌,加藤啓輔,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-17
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] ダウン症候群に合併した一過性骨髄異常増殖症148例の後方視的解析2010

    • Author(s)
      村松秀城, 他
    • Organizer
      第52回日本小児血液学会総会・第26回日本小児がん学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] CBL mutations in therapy-related leukemia and infant leukemia2010

    • Author(s)
      Shiba N, Taki T, Park MJ, Nagasawa M, Takita J, Kato M, Kanazaw T, Sotomatsu M, Arakawa H, Hayashi Y.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U. S. A
    • Year and Date
      2010-12-07
    • Related Report
      2011 Final Research Report
  • [Presentation] CBL mutations in therapy-related leukemia and infant leukemia.2010

    • Author(s)
      Shiba N, et al.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U.S.A.
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] LEF1 gene mutations in childhood T-cell acute lymphoblastic leukemia and T cell non-hodgkin's lymphoma2010

    • Author(s)
      Park MJ, Kiyokawa N, Kato M, Suzuki N, Oda M, Hara J, Kobayashi R, Horibe K, Ogawa S, Hayashi Y.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U. S. A
    • Year and Date
      2010-12-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Low-dose cytosine arabinoside therapy for neonates with down syndrome(DS) and transient leukemia(TL)2010

    • Author(s)
      Muramatsu H, Hayashi Y, Kawamura M, Kojima S, Yabe M, Isoyama K, Taki T, Tsuji K, Tsuchida M, Manabe A, Ito E, Iwamoto S, Kato H, Sumie A, Taga T, Nomura K, Hasegawa D, Watanabe K, Kikuchi A.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U. S. A
    • Year and Date
      2010-12-06
    • Related Report
      2011 Final Research Report
  • [Presentation] LEF1 gene mutations in childhood T-cell acute lymphoblastic leukemia and T cell non-hodgkin's lymphoma.2010

    • Author(s)
      Park MJ, et al.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U.S.A.
    • Year and Date
      2010-12-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] Low-dose cytosine arabinoside therapy for neonates with down syndrome (DS) and transient leukemia (TL).2010

    • Author(s)
      Muramatsu H, et al.
    • Organizer
      The 53rd ASH Annual Meeting and Exposition
    • Place of Presentation
      Orlando, U.S.A.
    • Year and Date
      2010-12-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肝機能障害を伴うTAMの臨床像について2010

    • Author(s)
      朴明子, 他
    • Organizer
      第114回小児血液腫瘍懇話会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 小児急性白血病と骨髄異形成症候群におけるCBL遺伝子の解析2010

    • Author(s)
      柴徳生, 朴明子, 林泰秀
    • Organizer
      第114回小児血液腫瘍懇話会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mutation analyses of CBL and MPL genes in childhood leukemia and myelodysplastic syndrome2010

    • Author(s)
      Shiba N, Kato M, Park MJ, Sanada M, Fukushima K, Kudo K, Hanada R, Ito E, Arakawa H, Ogawa S, Hayashi Y.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-26
    • Related Report
      2011 Final Research Report
  • [Presentation] Mutation analyses of CBL and MPL genes in childhood leukemia and myelodysplastic syndrome.2010

    • Author(s)
      Shiba N, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mutation analysis of lymphocyte tyrosine kinase(LTK) in acute lymphoblastic leukemia2010

    • Author(s)
      Uchisaka N, Kato M, Takita J, Sanada M, Nishimura R, Oki K, Okubo J, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Genome-wide analysis using high-density SNP microarrays in various types of hematologic malignancies2010

    • Author(s)
      Matsubara A, Kato M, Sanada M, Takita J, Chiba S, Hayashi Y, Kobayashi Y, Watanabe T, Yoshino T, Koeffler JP, Bartram CR, Ogawa S.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Mutations of LEF1 gene in pediatric T cell acute lymphoblastic leukemia2010

    • Author(s)
      Park MJ, Kato M, Kiyokawa N, Takita J, Ogawa S, Hayashi Y.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Internal deletions of transcription factor GATA1 observed in transient abnormal myelopoiesis2010

    • Author(s)
      Toki T, Kanezaki R, Wang RN, Terui K, Hayashi Y, Miura M, Maeda M, Ito E.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Mutation analysis of lymphocyte tyrosine kinase (LTK) in acute lymphoblastic leukemia.2010

    • Author(s)
      Uchisaka N, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Genome-wide analysis using high-density SNP microarrays in various types of hematologic malignancies.2010

    • Author(s)
      Matsubara A, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mutations of LEF1 gene in pediatric T cell acute lymphoblastic leukemia.2010

    • Author(s)
      Park MJ, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Internal deletions of transcription factor GATA1 observed in transient abnormal myelopoiesis.2010

    • Author(s)
      Toki T, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 小児悪性造血腫瘍におけるCBL遺伝子とMPL遺伝子の変異解析2010

    • Author(s)
      柴徳生,加藤元博,朴明子,真田昌,花田良二,伊藤悦朗,荒川浩一,小川誠司,林泰秀
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Genome-wide scanning of pediatric acute myeloied leukemia using SNP-genotyping microarrays2010

    • Author(s)
      Oki K, Takita J, Hiwatari M, Nishimura R, Sanada M, Ohkubo J, Uchisaka N, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Mutations of IDH1 and IDH2 in pediatric acute myeloid leukemia2010

    • Author(s)
      Oki K, Takita J, Hiwatari M, Nishimura R, Sanada M, Ohkubo J, Uchisaka N, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Genome-wide scanning of pediatric acute myeloied leukemia using SNP-genotyping microarrays.2010

    • Author(s)
      Oki K, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mutations of IDH1 and IDH2 in pediatric acute myeloid leukemia.2010

    • Author(s)
      Oki K, et al.
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胸膜肺芽腫における網羅的ゲノム解析2010

    • Author(s)
      大久保淳,滝田順子,大木健太郎,西村力,内坂直樹,安達正時,真田昌,加藤啓輔,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の関与2010

    • Author(s)
      滝田順子,西村力,大木健太郎,樋渡光輝,大久保淳,内坂直紀,真田昌,大喜多肇,藤本純一郎,金兼弘和,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児T細胞性造血器腫瘍におけるLEF1遺伝子の異常2010

    • Author(s)
      朴明子,加藤元博,清河信敬,滝田順子,小川誠司,林泰秀
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK阻害剤を用いた抗腫瘍効果の検討2010

    • Author(s)
      樋渡光輝,滝田順子,大久保淳,西村力,大木健太郎,内坂直樹,安達正時,真田昌,加藤啓輔,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 難治性小児固形腫瘍におけるALK変異と臨床応用2010

    • Author(s)
      西村力,滝田順子,真田昌,大久保淳,大木健太郎,加藤元博,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第7回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2010-05-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児白血病とMDSにおけるCBLとMPL遺伝子の解析2010

    • Author(s)
      柴徳生, 他
    • Organizer
      第7回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2010-05-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 小児白血病の発症,進展の分子遺伝学2010

    • Author(s)
      林泰秀
    • Organizer
      113回日本小児科学会学術集会(シンポジウム)
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-25
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児白血病の発症,進展の分子遺伝学2010

    • Author(s)
      林泰秀
    • Organizer
      113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 小児T細胞性急性リンパ性白血病における網羅的ゲノム解析2010

    • Author(s)
      朴明子,加藤元博,清河信敬,滝田順子,真田昌,小川誠司,林泰秀
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 若年性骨髄単球性白血病におけるCBL遺伝子の解析2010

    • Author(s)
      柴徳生,加藤元博,朴明子,真田昌,金澤崇,黒澤秀光,伊藤悦朗,荒川浩一,小川誠司,林泰秀
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Ewing/PNET familyにおけるALK遺伝子の解析2010

    • Author(s)
      滝田順子,西村力,大木健太郎,金兼弘和,大喜多肇,藤本純一郎,菊地陽,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 神経芽腫における部分欠損型ALKの活性化2010

    • Author(s)
      大木健太郎,滝田順子,西村力,加藤元博,陳玉彦,真田昌,菊地陽,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK阻害剤の効果に関する検討2010

    • Author(s)
      大久保淳,滝田順子,西村力,大木健太郎,加藤元博,真田昌,加藤啓輔,菊地陽,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 当科にて経験した血球貧食症候群12例の臨床的検討2010

    • Author(s)
      外松学, 他
    • Organizer
      第113回日本小児科学会学術集会
    • Place of Presentation
      岩手
    • Year and Date
      2010-04-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] ALK gene aberrations in pediatric solid tumors.2010

    • Author(s)
      Takita J, Nishimura R, Sanada M, Ohki K, Motohiro K, Chen YY, Kanegane H, Okita H, Fujimoto J, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      The 6th Congress of Asian Society for Pediatric Research & 51st Annual Meeting of Taiwan Pediatric Association
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2010-04-15
    • Related Report
      2011 Final Research Report
  • [Presentation] High resolution copy number analysis of Ewing sarcoma family of tumors using high-density SNP-genotyping microarrays2010

    • Author(s)
      Nishimura R, Takita J, Ohki K, Kato M, Chen YY, Sanada M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      The 6th Congress of Asian Society for Pediatric Research & 51st Annual Meeting of Taiwan Pediatric Association
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2010-04-15
    • Related Report
      2011 Final Research Report
  • [Presentation] ALK gene aberrations in pediatric solid tumors.2010

    • Author(s)
      Takita J, et al.
    • Organizer
      第6回小児研究アジア学会
    • Place of Presentation
      台北
    • Year and Date
      2010-04-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] High resolution copy number analysis of Ewing sarcoma family of tumors using high-density SNP-genotyping microarrays.2010

    • Author(s)
      Nishimura R, et al.
    • Organizer
      第6回小児研究アジア学会
    • Place of Presentation
      台北
    • Year and Date
      2010-04-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いた小児T細胞性腫瘍における網羅的ゲノム解析2010

    • Author(s)
      朴明子,加藤元博,清河信敬,滝田順子,真田昌,小川誠司,林泰秀
    • Organizer
      第8回日本臨床腫瘍学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-19
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 診断及び治療に難渋した慢性活動性EBウイルス感染症の一例2010

    • Author(s)
      一之宮健二, 他
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] CITA無効例に対する肝芽腫の治療についての検討2010

    • Author(s)
      朴明子
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 早期化学療法にて肝腫大縮小を得たIVs神経芽腫2010

    • Author(s)
      大竹紗耶香, 他
    • Organizer
      第20回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2010-02-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] CITA無効例に対するITECの有効性と治療関連毒性について-肝芽腫5症例の検討2010

    • Author(s)
      朴明子, 他
    • Organizer
      日本小児肝癌スタディグループ(JPLT)研究会2010
    • Place of Presentation
      東京
    • Year and Date
      2010-01-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Aberrant activation of ALK kinase by a short form ALK protein in neuroblastoma2010

    • Author(s)
      Okubo J, Takita J, Nishimura R, Oki K, Kato M, Chen Y, Sanada M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      Advances in Neuroblastoma Research
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2011 Final Research Report
  • [Presentation] Effects of selective ALK inhibitors to neuroblastoma.2010

    • Author(s)
      Takita J, Okubo J, Nishimura R, Oki K, Uchisaka N, Chen Y, Sanada M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      Advances in Neuroblastoma Research
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2011 Final Research Report
  • [Presentation] Aberrations of genes regulating NFκB pathway in B-cell malignant lymphoma2009

    • Author(s)
      Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Kawahata R, Niwa A, Chen y, Nakazaki K, Nomoto J, Asakura Y, Akatsuka Y, Hayashi Y, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S
    • Organizer
      第51回American Society of Hematology
    • Place of Presentation
      New Orleans
    • Year and Date
      2009-12-08
    • Related Report
      2011 Final Research Report
  • [Presentation] Down症候群に伴うtransient abnormal myelopoiesis(TAM)の予後因子についての検討2009

    • Author(s)
      朴明子,佐野弘純,小笠原水穂,嶋田明,外松学,井田孔明,林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2011 Final Research Report
  • [Presentation] NUP98遺伝子再構成を有する小児造血器腫瘍に同定された遺伝子変異とその臨床的意義2009

    • Author(s)
      竹谷健,滝智彦,福田誠司,山口清次,林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Down症候群に伴うtransient abnormal myelopoiesis (TAM)の予後因子についての検討2009

    • Author(s)
      朴明子
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規のリボソームタンパク遺伝子変異を認めたDiamond-Blackfan貧血の一例2009

    • Author(s)
      佐野弘純, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 術後4ヵ月で再発をきたした上腹部腹壁デスモイド腫瘍の一例2009

    • Author(s)
      若井公子, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 初診時にコンパートメント症候群を合併した血友病Aの1乳児例2009

    • Author(s)
      外松学, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] T細胞性急性リンパ性白血病におけるPTENとP13K-AKT経路の遺伝子解析2009

    • Author(s)
      朴明子,滝智彦,小田慈,八木啓子,小林良二,鈴木信寛,原純一,堀部敬三,林泰秀
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 神経芽腫における短縮型ALKによる活性化2009

    • Author(s)
      加藤元博,滝田順子,陳玉彦,大木健太郎,西村力,真田昌,井田孔明,菊地陽,小川誠司,林泰秀,五十嵐隆
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      大木健太郎,滝田順子,陳玉彦,西村力,加藤元博,金兼弘和,大喜多肇,藤本純一郎,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 高密度SNPアレイを用いたユーイング肉腫における網羅的ゲノム解析2009

    • Author(s)
      西村力,滝田順子,大木健太郎,加藤元博,陳玉彦,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 悪性奇形腫群腫瘍の治療成績と問題点2009

    • Author(s)
      黒岩実, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 異なる病理組織像の急性虫垂炎を合併した白血病の2症例2009

    • Author(s)
      橘木浩平, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 東京小児がん研究グループ急性リンパ性白血病第16次治療研究におけるマーカー中央診断2009

    • Author(s)
      清河信敬, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] TCCSG-L1602治療研究におけるDay8末梢血-芽球数のフローサイトメトリー測定についての評価2009

    • Author(s)
      恩田恵子, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 21 trisomyと小児急性リンパ性白血病2009

    • Author(s)
      加藤元博, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小児急性骨髄性白血病におけるWT1遺伝子変異と臨床像2009

    • Author(s)
      佐野弘純,久保田知里,朴明子,嶋田明,外松学,滝智彦,田渕健,多和昭雄,堀部敬三,土田昌宏,花田良二,月本一郎,林泰秀
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児B細胞性リンパ腫のマイクロアレイを用いたmolecular karyotypingと網羅的発現遺伝子解析2009

    • Author(s)
      清河信敬,恩田恵子,飯島一智,長谷川大輔,加藤元博,大喜多肇,齋藤正博,森鉄也,真部淳,康勝好,小原明,林泰秀,花田良二,土田昌宏,中川温子,小川誠司,藤本純一郎
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児B細胞性リンパ腫のマイクロァレイを用いたmolecular kalyotypingと網羅的発現遺伝子解析2009

    • Author(s)
      清河信敬, 他
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Japanese pedigree with RUNX1 mutation resulting in FPD/AML2009

    • Author(s)
      Hasegawa D, Ogawa C, Hirabayashi S, Park MJ, Hayashi Y, Manabe A, Hosoya R.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Clinical sighificance of somatic mutations in hematological malignancies with NUP98-fusion genes2009

    • Author(s)
      Taketani T, Taki T, Fukada S, Yamaguchi S, Hayashi Y
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Molecular allelo-karyotype of adult acute lymphoblastic leukemia(ALL) and pediatric ALL2009

    • Author(s)
      Okubo J, Kato M, Takita J, Sanada M, Ohki K, Nishimura R, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2011 Final Research Report
  • [Presentation] A Japanese pedigree with RUNX1 mutation resulting in FPD/AML.2009

    • Author(s)
      Hasegawa D, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Clinical sighificance of somatic mutations in hematological malignancies with NUP98-fusion genes.2009

    • Author(s)
      Taketani T, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular allelo-karyotype of adult acute lymphoblastic leukemia(ALL) and pediatric ALL.2009

    • Author(s)
      Okubo J, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Frequent inactivation of A20 throuh gene mutation in B-cell lymphomas2009

    • Author(s)
      Kato M, Sanada M, Kato I, Sato Y, Takita J, Takeuchi K, Niwa A, Chen Y, Nakazaki K, Nomoto J, Asakura Y, Akatsuka Y, Hayashi Y, Mori H, Igarashi T, Kurokawa M, Chiba S, Mori S, Ishikawa Y, Okamoto K, Tobinai K, Nakagama H, Nakahata T, Yoshino T, Kobayashi Y, Ogawa S
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Genome-wide analysis of pediatric T-cell acute lymphoblastic leukemia2009

    • Author(s)
      Park MJ, Kato M, Kiyokawa N, Sanada M, Takita J, Ogawa S, Hayashi Y.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2011 Final Research Report
  • [Presentation] 東京小児がん研究グループにて1981年から1999年の5つの研究に登録された小児急性リンパ性白血病2035例の長期追跡結果2009

    • Author(s)
      土田昌宏, 他
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Genome-wide analysis of pediatric T-cell acute lymphoblastic leukemia.2009

    • Author(s)
      Park MJ, et al.
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] 各種腫瘍における高密度SNPアレイを用いた網羅的ゲノムプロファイリング2009

    • Author(s)
      松原亜以子,加藤元博,真田昌,滝田順子,千葉滋,林泰秀,小俣政男,小林幸夫,渡邉俊樹,石川雄一,吉野正,小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の増幅と変異2009

    • Author(s)
      滝田順子,大木健太郎,西村力,加藤元博,陳玉彦,真田昌,金兼弘和,大喜多肇,藤本純一郎,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児T細胞型急性リンパ性白血病における網羅的ゲノム解析2009

    • Author(s)
      朴明子,加藤元博,清河信敬,真田昌,滝田順子,小川誠司,林泰秀
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK阻害剤の感受性2009

    • Author(s)
      本村あい,滝田順子,大木健太郎,西村力,加藤元博,陳玉彦,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-03
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] ユーイング肉腫における高密度SNPアレイによる網羅的遺伝子解析2009

    • Author(s)
      西村力,滝田順子,大木健太郎,加藤元博,陳玉彦,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 神経芽細胞腫のALK遺伝子異常によるALKキナーゼ活性の異常増幅2009

    • Author(s)
      大木健太郎,滝田順子,西村力,加藤元博,陳玉彦,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] 神経芽細胞腫のALK遺伝子異常によるALKキナーゼ活性の以上増幅2009

    • Author(s)
      大木健太郎, 他
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Opsoclonus-myoclonus症候群を契機に診断された神経芽腫の一例2009

    • Author(s)
      佐野弘純, 他
    • Organizer
      第19回群馬小児がん研究会
    • Place of Presentation
      前橋
    • Year and Date
      2009-08-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 若年性骨髄単球性白血病(JMML)のゲノム解析2009

    • Author(s)
      加藤元博, 他
    • Organizer
      厚生労働省がん研究助成金/厚生労働科学研究費補助金藤本班・堀部班・石田班合同班会議
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] T細胞性急性リンパ性白血病におけるPTENとPI3K-AKT経路の遺伝子解析2009

    • Author(s)
      朴明子, 他
    • Organizer
      厚生労働省がん研究助成金/厚生労働科学研究費補助金藤本班・堀部班・石田班合同班会議
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] MLPA (Multiple Ligation-dependent Probe Amplification)法による染色体全サブトロメア微細構造異常の網羅的解析2009

    • Author(s)
      吉橋博史, 他
    • Organizer
      第181回日本小児科学会群馬地方会講話会
    • Place of Presentation
      高崎
    • Year and Date
      2009-06-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子, 他
    • Organizer
      第6回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2009-05-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] RUNX1変異を伴ったfamilial platelet disorder with propensity to acute myelogeneous leukemia (FPD/AML)-家系2009

    • Author(s)
      長谷川大輔, 他
    • Organizer
      第6回北関東小児がんセミナー
    • Place of Presentation
      高崎
    • Year and Date
      2009-05-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 神経芽腫におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子,陳玉彦,加藤元博,大平美紀,菊地陽,中川原章,野間博行,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児がんにおける網羅的なLoss of heterozygosity(LOH)解析2009

    • Author(s)
      加藤元博,滝田順子,陳玉彦,真田昌,大木健太郎,滝智彦,菊地陽,林泰秀,小川誠司,五十嵐隆
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児がんにおける網羅的なLoss of heterozygosity (LOH)解析2009

    • Author(s)
      加藤元博, 他
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 超高密度オリゴヌクレオチドアレイを用いた小児横紋筋肉腫における網羅的ゲノム解析2009

    • Author(s)
      大木健太郎,滝田順子,加藤元博,陳玉彦,真田昌,林泰秀,五十嵐隆,小川誠司
    • Organizer
      第112回日本小児科学会学術集会
    • Place of Presentation
      奈良
    • Year and Date
      2009-04-17
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子,大木健太郎,西村力,陳玉彦,加藤元博,金兼弘和,大喜多肇,藤本純一郎,真田昌,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第54回日本人類遺伝学会第54回大会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 各種腫瘍における高密度SNPアレイを用いた網羅的ゲノムプロファイリング2009

    • Author(s)
      松原亜以子,加藤元博,真田昌,滝田順子,千葉滋,林泰秀,小俣政男,小林幸夫,渡邉俊樹,石川雄一,吉野正,小川誠司, Koeffler HP, Bratram CR.
    • Organizer
      第54回日本人類遺伝学会,第54回大会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report
  • [Presentation]2009

    • Author(s)
      加藤元博,真田昌,加藤格,佐藤康晴,滝田順子,竹内賢吾,丹羽明,陳玉彦,中崎久美,野本順子,川幡亮一郎,朝倉義崇,赤塚美樹,林泰秀,森啓,五十嵐隆,黒川峰夫,千葉滋,森茂郎,石川雄一,岡本康司,飛内賢正,中釜斉,中畑龍俊,吉野正,小林幸夫,小川誠司
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児固形腫瘍におけるALK遺伝子の解析2009

    • Author(s)
      滝田順子,西村力,大木健太郎,陳玉彦,加藤元博,真田昌,金兼弘和,大喜多肇,藤本純一郎,菊地陽,五十嵐隆,林泰秀,小川誠司
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 小児固形腫瘍の診断および治療効果判定におけるMRI拡散強調画像の有効性について2009

    • Author(s)
      佐野弘純, 他
    • Organizer
      第51回日本小児血液学会、第25回日本小児がん学会
    • Place of Presentation
      千葉
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.gcmc.pref.gunma.jp/

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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