Nanomicro-therapy for pregnancy-induced hypertension

• Project/Area Number: 21390320
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Embryonic/Neonatal medicine
• Research Institution: Tohoku University
• Principal Investigator: OKAMURA Kunihiro 東北大学, 大学院・医学系研究科, 名誉教授 (90124560)
• Co-Investigator(Kenkyū-buntansha): OHTA Hidenobu 東北大学, 大学院・医学系研究科, 非常勤講師 (80422103) ; CHISAKA Hiroshi 東北大学, 大学院・医学系研究科, 非常勤講師 (40323026)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000); Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2010: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2009: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
• Keywords: 妊娠高血圧症候群 / 胎児低酸素症 / 人工赤血球

Research Abstract

This research aims to develop a new method to treat fetal hypoxia under pregnancy-induced hypertension with an artificial oxygen carrier. Using a rat model, we investigated appropriate does of an artificial oxygen carrier for treatment and also examined the safety of the artificial oxygen carrier for fetal development.