Assessment of individual circadian phenotypes using biopsy samples-Application to Circadian Rhythm Sleep Disorder patients-
| Project/Area Number |
21390335
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
MISHIMA Kazuo 独立行政法人国立精神・神経医療研究センター, 精神保健研究所精神生理研究部, 部長 (40239223)
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| Co-Investigator(Kenkyū-buntansha) |
HIDA Akiko 独立行政法人国立精神・神経医療研究センター, 精神保健研究所精神生理研究部, 室長 (20333354)
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| Research Collaborator |
KITAMURA Shingo 独立行政法人国立精神・神経医療研究センター, 精神保健研究所精神生理研究部, 流動研究員 (80570291)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2009: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Keywords | 精神生理学 / 生物リズム / 時計遺伝子 / 強制脱同調 |
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| Research Abstract |
In this study, sleep timing was compared between married Japanese couples(n=225) who had lived together for 1 yr or more(mean 17 yrs). Additionally, the authors evaluated the influence of individual traits and environmental factors on an individual's sleep timing per each couple. The results reveal that the sleep timings of a couple are mainly associated with the chronotypes of the husband and wife, whereas the sleep timings are significantly influenced by certain environmental factors. The findings suggest that chronotype remains one of the major determinants of an individual's sleep onset and wake times. Understanding an individual's chronotype may help improve the quality of life issues surrounding sleep.
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Report
(4 results)
Research Products
(63 results)
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[Presentation] 【Oral】Assessment of individual circadian phenotypes using biopsy samples2011
Author(s)
Hida A, Kitamura S, Watanabe M, Enomoto M, Katayose Y, Aritake S, Higuchi S, Kato M, Moriguchi Y, Ikeda M, Mishima K
Organizer
Neuroscience 2011
Place of Presentation
Washington, DC
Related Report
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[Presentation] 【Poster】Circadian characteristics in nonentrained type of circadian rhythm sleep disorder2011
Author(s)
Kitamura S, Hida A, Watanabe M, Enomoto M, Katayose Y, Nozaki K, Aritake-Okada S, Higuchi S, Moriguchi Y, Kamei Y, Mishima K
Organizer
Neuroscience 2011
Place of Presentation
Washington, DC
Related Report
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[Presentation] 【Poster】Evaluation of individual's circadian clock properties at physiological and molecular levels2011
Author(s)
Hida A, Kitamura S, Watanabe M, Enomoto M, Aritake S, Higuchi S, Nozaki K, Kato M, Moriguchi Y, Mishima K
Organizer
SLEEP 2011, 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC(APSS)
Place of Presentation
Minneapolis, Minnesota(USA)
Related Report
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[Presentation] Association study of circadian gene polymorphisms with circadian sleep disorders in Japanese population2010
Author(s)
Hida A, Watanabe M, Kato M, Kitamura S, Enomoto M, Moriguchi Y, Kamei Y, Kadotani H, Uchiyama M, Inoue Y, Takahashi K, Mishima K
Organizer
20th Congress of the European Sleep Research Society
Place of Presentation
Lisbon, Portugal
Related Report
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