| Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Research Abstract |
Geiger-mode avalanche photodiode(Si-PM) is a promising photodetector for PET, especially for use in a magnetic resonance imaging(MRI) system because it has high gain and is less sensitive to static magnetic field. We developed a Si-PM based depth-of-interaction(DOI) PET system for small animals. Hamamatsu 4x4 Si-PM arrays(S11065-025P) were used for its detector blocks. Two types of LGSO scintillator of 0.75 mol% Ce(decay time :～ 45ns : 1.1mm x 1.2mm x 5mm) and 0.025 mol% Ce(decay time :～ 31ns : 1.1mm x 1.2mm x 6mm) were optically coupled in the DOI direction to form a DOI detector, arranged in 11 x 9 matrix, and optically coupled to the Si-PM array. Pulse shape analysis was used for the DOI detection of these two types of LGSOs. Sixteen detector blocks were ar-ranged in a 68mm diameter ring to form the PET system. Spatial resolution was 1.6mm FWHM and sensitivity was 0.6% at the center of the field-of-view. High resolution mouse and rat images were successfully obtained using the PET system. Simultaneous imaging with MRI was possible with some loss of the signal to noise ratio(S/N).
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