Development of DOI detectors by the use of new semiconductor based photo-detectors and their application to wearable PET systems
Project/Area Number |
21390351
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Radiation science
|
Research Institution | Kobe City College of Technology |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
HATAZAWA Jun 大阪大学, 医学系研究科, 教授 (70198745)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
|
Keywords | PET / 高分解能 / 高感度 / 分子イメージング / 光センサー / ウエアラブル / シリコンPM / 半導体 / PET/MRI / 相互影響 / シリコンフォトマル / LGSO / DOI / 波形解析 / Si-PM / 発光減衰時間 |
Research Abstract |
Geiger-mode avalanche photodiode(Si-PM) is a promising photodetector for PET, especially for use in a magnetic resonance imaging(MRI) system because it has high gain and is less sensitive to static magnetic field. We developed a Si-PM based depth-of-interaction(DOI) PET system for small animals. Hamamatsu 4x4 Si-PM arrays(S11065-025P) were used for its detector blocks. Two types of LGSO scintillator of 0.75 mol% Ce(decay time :~ 45ns : 1.1mm x 1.2mm x 5mm) and 0.025 mol% Ce(decay time :~ 31ns : 1.1mm x 1.2mm x 6mm) were optically coupled in the DOI direction to form a DOI detector, arranged in 11 x 9 matrix, and optically coupled to the Si-PM array. Pulse shape analysis was used for the DOI detection of these two types of LGSOs. Sixteen detector blocks were ar-ranged in a 68mm diameter ring to form the PET system. Spatial resolution was 1.6mm FWHM and sensitivity was 0.6% at the center of the field-of-view. High resolution mouse and rat images were successfully obtained using the PET system. Simultaneous imaging with MRI was possible with some loss of the signal to noise ratio(S/N).
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Report
(4 results)
Research Products
(27 results)