Adipocytokine is the new target of the strategy for the prevention of intimal hyperplasia
Project/Area Number |
21390357
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
General surgery
|
Research Institution | Nagoya University |
Principal Investigator |
KOMORI Kimihiro 名古屋大学, 大学院・医学系研究科, 教授 (40225587)
|
Co-Investigator(Kenkyū-buntansha) |
MUROHARA Toyoaki 名古屋大学, 大学院・医学系研究科, 教授 (90299503)
SHIBATA Rei 名古屋大学, 大学院・医学系研究科, 特任講師 (70343689)
YAMAMOTO Kiyohito 名古屋大学, 医学部附属病院, 講師 (10298359)
KOBAYASHI Masayoshi 名古屋大学, 医学部附属病院, 助教 (60329381)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
|
Keywords | 脂肪細胞由来因子 / 血管内膜肥厚 / 自家静脈グラフト |
Research Abstract |
Pioglitazone attenuates intimal hyperplasia of the vein graft after autologous bypass grafting by its ability to suppress cell proliferation and enhance apoptosis. Pioglitazone could represent a therapeutic target for the prevention of graft failure after bypass grafting.
|
Report
(4 results)
Research Products
(83 results)
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[Journal Article] Cost disparity between open repair and endovascular aneurysm repair for abdominal a ortic aneurysm2012
Author(s)
Morimae H, Maekawa T, Tamai H, Takahashi N, Ihara T, Hori A, NaritaH, Banno H, Kobayashi M, Yamamoto K, Komori K
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Journal Title
Japan Surg Today
Volume: 42
Pages: 121-126
Related Report
Peer Reviewed
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[Journal Article] Cost disparity between open repair and endovascular aneurysm repair for abdominal aortic aneurysm : a single-institute experience in Japan2012
Author(s)
Morimae H, Maekawa T, Tamai H, Takahashi N, Ihara T, Hori A, Narita H, Banno H, Kobayashi M, Yamamoto K, Komori K
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Journal Title
Surg Today
Volume: 42
Pages: 121-126
NAID
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Peer Reviewed
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[Journal Article]2009
Author(s)
杉本昌之, 古森公浩
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Journal Title
閉塞性動脈硬化症 (PAD) 診療の実践~間欠性跛行に対するアプローチー(南江堂)
Pages: 22-24
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[Journal Article]2009
Author(s)
古森公浩
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Journal Title
標準血管外科学II日本血管外科学教育セミナーテキスト(メディカルトリビューン)
Pages: 88-94
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[Journal Article]2009
Author(s)
古森公浩
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Journal Title
標準血管外科学II日本血管外科学教育セミナーテキスト(メディカルトリビューン)
Pages: 123-126
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[Journal Article]2009
Author(s)
出津明仁, 古森公造
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Journal Title
ENDOVASCULAR TREATMENT EVTテクニックこれは困ったどうしよう!(中外医学社)
Pages: 42-43
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[Presentation] 血管病治療の最前線2011
Author(s)
古森公浩
Organizer
第25回日本血管外科学会近畿地方会
Place of Presentation
和歌山県立医科大学高度医療人育成センター5F
Year and Date
2011-03-12
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[Presentation] SARPOGRELATE HYDROCHLORIDE MODULATES THE EXPRESSION OF 5-HYDROXYTRYPTAMINE TYPE 2A AND TYPE 1B RECEPTORS IN EXPERIMENTAL RABBIT VEIN GRAFTS2009
Author(s)
Kodama A, Tamai H, Idetsu A, Morimae H, Hori A, Narita H, Kobayashi M, Yamamoto K, Kajikuri J, Itoh T, Komori K
Organizer
10th MOVD 2009, 10th International Symposium on Mechanisms of Vasodilatation
Place of Presentation
Matsushima, Miyagi
Year and Date
2009-06-03
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