| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Research Abstract |
Based on the gene expression of rectal cancer, we aimed to build a predictive model for response to chemoradiotherapy. Using 46 samples as a training set, we examined gene expression by microarray and RT-PCR. We finally selected 4 genes that were used for predictive model. The accuracy rate of prediction was 89.1% among a training set. In an independent test set of 16 samples, we validated the accuracy of a predictive model and the accuracy rate of the predictive model was 81.3%.
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