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Development of hybrid therapy of myocardial regenerative medicine and ventricular assist circulation to improve prognosis of heart transplant candidate

Research Project

Project/Area Number 21390398
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionNational Cardiovascular Center Research Institute

Principal Investigator

TAKEWA Yoshiaki  独立行政法人国立循環器病研究センター, 研究所, 室長 (20332405)

Co-Investigator(Kenkyū-buntansha) TAENAKA Yoshiyuki  独立行政法人国立循環器病研究センター, 研究所, 副所長 (00142183)
TATSUMI Eisuke  独立行政法人国立循環器病研究センター, 研究所, 部長 (00216996)
Co-Investigator(Renkei-kenkyūsha) HONMA Akihiko  独立行政法人国立循環器病研究センター, 研究所, 室長 (20287428)
SUMIKURA Hirohito  独立行政法人国立循環器病研究センター, 研究所, 研究員 (20433998)
OHNUMA Kentarou  独立行政法人国立循環器病研究センター, 研究所, 研究員 (50527992)
HANADA Shigeru  独立行政法人国立循環器病研究センター, 研究所, 研究員 (90514547)
KAKUTA Yukihide  独立行政法人国立循環器病研究センター, 研究所, 研究員 (30443485)
FUJII Yutaka  独立行政法人国立循環器病研究センター, 研究所, 研究員 (20589303)
TAKAKI Miyako  奈良県立医科大学, 医学部, 教授 (00033358)
MIZUGUCHI Hiroyuki  大阪大学, 薬学研究科, 教授 (50311387)
Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Keywords心臓大血管外科学 / 心筋再生療法 / 遺伝子導入 / 重症不全心 / カチオン性合成ベクター / 遺伝子デリバリー法 / SERCA2a / 左心補助循環 / 定常流ポンプ / cross clamping法
Research Abstract

We created a heart failure model of large animals (adult goats), conducted a continuous flow left ventricular assist circulation, transferred SERCA2a gene, which can increase the myocardial contractility, and investigated whether this hybrid therapy could improve and recover the cardiac function. In terms of assist circulation, a synchronized alteration of rotational speed of a continuous flow pump was effective to accelerate the myocardial recovery. Additional gene therapy could increase the myocardial contractility. The synergistic effect of ventricular assist and myocardial regenerative medicine showed the potential to improve prognosis of heart failure patients such as heart transplant candidates

Report

(5 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (199 results)

All 2013 2012 2011 2010 2009

All Journal Article (33 results) (of which Peer Reviewed: 32 results) Presentation (166 results)

  • [Journal Article] Development of a novel drive mode to prevent aortic insufficiency during continuous-flow LVAD support by synchronizing rotational speed with heartbeat.2013

    • Author(s)
      Kishimoto Y, Takewa Y, Arakawa M, Umeki A, Ando M, NishimuraT, Fujii Y, Mizuno T, Nishimura M, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: (Epubのみ頁未定)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Change in myocardial oxygen consumption employing continuous-flow LVAD with cardiac beat synchronizing system, in acute ischemic heart failure models.2013

    • Author(s)
      Umeki A, Nishimura T, Takewa Y, Ando M, Arakawa M, Kishimoto Y, Tsukiya T, Mizuno T, Kyo S, Ono M, Taenaka Y, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: (Epub のみ頁未定)

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model.2013

    • Author(s)
      Fujii Y, Shirai M, Inamori S, Shimouchi A, Sonobe T, Tsuchimochi H, Pearson JT, Takewa Y, Tatsumi E, Taenaka Y.
    • Journal Title

      Artif Organs.

      Volume: 37 Issue: 2 Pages: 136-141

    • DOI

      10.1111/j.1525-1594.2012.01535.x

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development and evaluation of endurance test system for ventricular assist devices.2013

    • Author(s)
      Sumikura H, Homma A, Ohnuma K, Taenaka Y, Takewa Y, Mukaibayashi H, Katano K, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: Feb 12

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a novel drive mode to prevent aortic insufficiency during continuous-flow LVAD support by synchronizing rotational speed with heartbeat.2013

    • Author(s)
      Kishimoto Y, Takewa Y, Arakawa M, Umeki A, Ando M, Nishimura T, Fujii Y, Mizuno T, Nishimura M, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: Jan 23

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coronary vascular resistance increases under fullbypasssupport of centrifugal pumps-relation between myocardial perfusion and ventricular workload during pump support2012

    • Author(s)
      Ando M, Takewa Y, Nishimura T, et al
    • Journal Title

      Artif Organs

      Volume: 36 Issue: 1 Pages: 105-110

    • DOI

      10.1111/j.1525-1594.2011.01298.x

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vivo evaluation of an in-body, tissue-engineered, completely autologous valved conduit (biovalve type VI) as an aortic valve in a goat model.2012

    • Author(s)
      Takewa Y, Yamanami M, Kishimoto Y, Arakawa M, Kanda K, Matsui Y, Oie T, Ishibashi-Ueda H, Tajikawa T, Ohba K, Yaku H, Taenaka Y, Tatsumi E, Nakayama Y
    • Journal Title

      J Artif Organs

      Volume: Dec 20

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the technique for assisting renal blood circulation on ischemic kidney in acute cardiorenal syndrome.2012

    • Author(s)
      Hanada S, Takewa Y, Mizuno T, Tsukiya T, Taenaka Y, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: 15 Issue: 2 Pages: 140-145

    • DOI

      10.1007/s10047-011-0613-5

    • NAID

      10030807467

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coronary vascular resistance increases under full bypass support of centrifugal pumps-Relation between myocardial perfusion and ventricular workload during pump support2012

    • Author(s)
      Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
    • Journal Title

      Artificial Organs

      Volume: 36 Pages: 105-110

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Creating an ideal off-test mode for rotary left ventricular assist devices : Establishing a safe and appropriate weaning protocol after myocardial recovery2011

    • Author(s)
      Ando M, Nishimura T, et al.
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: 143 Issue: 5 Pages: 1176-1182

    • DOI

      10.1016/j.jtcvs.2011.07.065

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Alteration of LV end-diastolic volume by controlling the power of the continuous-flow LVAD, so it is synchronized with cardiac beat : development of a native heart load control system (NHLCS)2011

    • Author(s)
      Umeki A, Nishimura T, et al.
    • Journal Title

      J Artif Organs

      Volume: 11 Issue: 2 Pages: 1-6

    • DOI

      10.1007/s10047-011-0615-3

    • NAID

      10030807433

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Electrocardiogram-Synchronized Rotaional Speed Change Mode in Rotary Pumps Could Improve Pulatility2011

    • Author(s)
      Masahiko Ando, Takashi Nishimura, Kenji Yamazaki, Shunei Kyo, Minoru Ono, Tomonori Tsukiya, Toshihide Muzuno, Yoshiyuki Taenaka, Eisuke Tatsumi
    • Journal Title

      Artificial Organs

      Volume: 35 Issue: 10 Pages: 941-947

    • DOI

      10.1111/j.1525-1594.2011.01205.x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel counterpulsation mode of rotary left ventricular assist devices can enhance myocardial perfusion.2011

    • Author(s)
      Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: 14 Issue: 3 Pages: 185-191

    • DOI

      10.1007/s10047-011-0573-9

    • NAID

      10031177187

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation?Intracircuit back-flow analysis in a mock cirsulation model2011

    • Author(s)
      Masahiko Ando, Takashi Nishimura, Yoshiaki Takewa, Daisuke Ogawa, Kenji Yamazaki, Koichi Kashiwa, Shunei Kyo, Minoru ONo, Yoshiyuki Taenaka, Eisuke Tatsumi
    • Journal Title

      Journal of Artificial Organs

      Volume: 14 Issue: 1 Pages: 70-73

    • DOI

      10.1007/s10047-010-0543-7

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel counerpulse drive mode of continuous-flow left ventricular assist devices can minimize intrciucuit backward flow suring pump weaning2011

    • Author(s)
      Masahiko Ando, Takashi Nishimura, Yoshiaki Takewa, Daisuke Ogawa, Kenji Yamazaki, Koichi Kashiwa, Shunei Kyo, Minoru Ono, Yoshiyuki Taenaka, Eisuke Tatsumi
    • Journal Title

      Journal of Artificial Organs

      Volume: 14 Issue: 1 Pages: 74-79

    • DOI

      10.1007/s10047-010-0544-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development and Hydrodynamic Evaluation of a novel inflow cannula in a mechanical circulatory support system for bridge to decision.2011

    • Author(s)
      Sumikura H, Toda K, Takewa Y, Tsukiya T, Ohnuma K, Sasagawa M, Watanabe F, Ugawa J, Taenaka Y, Tatsumi E.
    • Journal Title

      Artif Organs

      Volume: 35 Issue: 8 Pages: 7516-764

    • DOI

      10.1111/j.1525-1594.2011.01319.x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a pre-clinical model of ischemic cardiomyopathy in swine2011

    • Author(s)
      Ishikawa K, Ladage D, Takewa Y, Yaniz E, Chen J, Tilemann L, Sakata S, Badimon JJ, Hajjar RJ & Kawase Y
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 301 Issue: 2 Pages: H530-H537

    • DOI

      10.1152/ajpheart.01103.2010

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Computational fluid dynamic analysis of the flow field in the newly developed inflow cannula for a bridge-to-decision mechanical circulatory support.2011

    • Author(s)
      Tsukiya T, Toda K, Sumikura H, Takewa Y, Watanabe F, Taenaka Y, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: 14 Issue: 4 Pages: 381-384

    • DOI

      10.1007/s10047-011-0599-z

    • NAID

      10030339558

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Computational fluid dynamic analysis of the flow field in the newly developed inflow cannula for a bridge-to-decision mechanical circulatory support2011

    • Author(s)
      Tsukiya T, Toda K, Sumikura H, Takewa Y, Watanabe F, Taenaka Y, Tatsumi E
    • Journal Title

      J Artif Organs

      Volume: 14 Pages: 381-384

    • NAID

      10030339558

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a preclinical model of ischemic cardiomyopathy in swine2011

    • Author(s)
      Ishikawa K, Ladage D, Takewa Y, Yaniz E, Chen J, Tilemann L, Sakata S, Badimon JJ, Hajjar RJ, Kawase Y
    • Journal Title

      Am J Physiol-Heart C

      Volume: 301

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development and Hydrodynamic Evaluation of a novel inflow cannula in a mechanical circulatory support system for bridge to decision2011

    • Author(s)
      Sumikura H, Toda K, Takewa Y, Tsukiya T, Ohnuma K, Sasagawa M, Watanabe F, Ugawa J, Taenaka Y, Tatsumi E
    • Journal Title

      Artificial Organs

      Volume: 35 Pages: 756-764

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development and long-term in vivo testing of a novel skin-button system for preventing driveline infection of an implantable VAD system2011

    • Author(s)
      Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
    • Journal Title

      J Artif Organs

      Volume: 14 Pages: 371-374

    • NAID

      10030339521

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel couterpulse drive mode of continuous-flow left ventricular assist devices can minimize intracircuit backward flow during pump weaning2011

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, Kyo S, Ono M, Taenaka Y, Tatsumi E
    • Journal Title

      J Artif Organs

      Volume: 14 Pages: 74-79

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation? Intracircuit back-flow analysis in a mock circulation model2011

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, Kyo S, Ono M, Taenaka Y, Tatsumi
    • Journal Title

      J Artif Organs

      Volume: 14 Pages: 70-73

    • NAID

      10029565771

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel counterpulsation mode of rotary left ventricular assist devices can enhance myocardial perfusion2011

    • Author(s)
      Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
    • Journal Title

      J Artif Organs

      Volume: 14 Pages: 185-191

    • NAID

      10031177187

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility2011

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Ono M, Tsukiya T, Mizuno T, Taenaka Y, Tatsumi E
    • Journal Title

      Artificial Organs

      Volume: 35 Pages: 941-947

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel counterpulse drive mode of continuous-flow left ventricular assist devices can minimize intracircuit backward flow during pump weaning.2011

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, Kyo S, Ono M, Taenaka Y, Tatsumi E.
    • Journal Title

      J Artif Organs

      Volume: 14(1) Pages: 74-9

    • NAID

      10029565778

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 空気駆動式ウェアラブル全人工心臓システムの開発2010

    • Author(s)
      本間章彦、住倉博仁、大沼健太郎、妙中義之、巽英介、武輪能明、赤川英毅、水野敏秀、築谷朋典、片桐伸将、角田幸秀、福井康裕、下崎勇生、向林宏、片野一夫
    • Journal Title

      電気学会研究会資料

      Volume: LD-10 Pages: 57-61

    • NAID

      10027632917

    • Related Report
      2010 Annual Research Report
  • [Journal Article] In vivo myocardial distribution of multipotent progenitor cells following intracoronary delivery in a swine model of myocardial infarction.2009

    • Author(s)
      Ly HQ, Hoshino K, Pomerantseva I, Kawase Y, Yoneyama R, Takewa Y, Fortier A, Gibbs-Strauss SL, Vooght C, Frangioni JV, Hajjar RJ.
    • Journal Title

      Eur Heart J.

      Volume: 30(23) Issue: 23 Pages: 2861-2868

    • DOI

      10.1093/eurheartj/ehp322

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of molecular weight in four-branched star vectors with narrow molecular weight distribution on gene delivery efficiency.2009

    • Author(s)
      Nemoto Y, Borovkov A, Zhou YM, Takewa Y, Tatsumi E, Nakayama Y.
    • Journal Title

      Bioconjug Chem.

      Volume: 20 Issue: 12 Pages: 2293-2299

    • DOI

      10.1021/bc900283h

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats.2009

    • Author(s)
      Takewa Y, Chemaly ER, Takaki M, Liang LF,Jin H, Karakikes I, Morel C, Taenaka Y, Tatsumi E, Hajjar RJ.
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 296 Issue: 4 Pages: H1117-H1124

    • DOI

      10.1152/ajpheart.01120.2008

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats.2009

    • Author(s)
      Takewa Y, Chemaly ER, Takaki M, Liang LF, Jin H, Karakikes I, Morel C, Taenaka Y, Tatsumi E, Hajjar RJ
    • Journal Title

      Am J Physiol Heart Circ Physiol. 296

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of molecular weight in four-branched star vectors with narrow molecular weight distribution on gene delivery efficiency.2009

    • Author(s)
      Nemoto Y, Borovkov A, Zhou YM, Takewa Y, Tatsumi E, Nakayama Y.
    • Journal Title

      Bioconjug Chem. 20

      Pages: 2293-9

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 医療機器の動物実験による評価方法2013

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、巽 英介
    • Organizer
      バイオエンジニアリング研究会 (25)
    • Place of Presentation
      つくば
    • Related Report
      2012 Annual Research Report
  • [Presentation] 抗血栓性コーティングの性能及び特性の定量的評価法の検討2013

    • Author(s)
      水野敏秀、山岡哲二、築谷朋典、武輪能明、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 非接触駆動が可能なディスポーザブル遠心ポンプの開発2013

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、星 英男、大久保 剛、巽 英介、妙中義之
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] VVECMO を効率よく行うには?カニュレーション位置からの検討2013

    • Author(s)
      東郷好美、武輪能明、水野敏秀、築谷朋典、岸本祐一郎、荒川 衛、熱田 祐一、片桐 伸将、角田幸秀、藤井 豊、住倉博仁、大沼健太郎、妙中義之、宮本祐冶、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 拍動流型LVASの拍動数が心拍変動及び自律神経活動へ与える影響2013

    • Author(s)
      岸本祐一郎、大沼健太郎、荒川 衛、岸本 諭、水野敏秀、赤川英毅、武輪能明、西村元延、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 確率的手法を用いた自律的人工心臓駆動のための基礎的検討2013

    • Author(s)
      大沼健太郎、住倉博仁、本間章彦、武輪能明、水野敏秀、築谷朋典、赤川英毅、福井康裕、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 自己心拍同期回転数制御システムによる定常流型LVADの拍動性増大効果-慢性心不全モデルにおける長期検討-2013

    • Author(s)
      荒川 衛、武輪能明、西村 隆、梅木昭秀、安藤政彦、岸本祐一郎、許 俊鋭、安達秀雄、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流LVADの心電図同期変動回転駆動における消費電力に関する考察2013

    • Author(s)
      安藤政彦、西村 隆、武輪能明、築谷朋典、水野敏秀、山崎健二、許 俊鋭、小野 稔、妙中、義之、巽 英介、
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 送脱血カニューレおよびドライブライン出口部周囲における皮膚性状の経時的変化と細菌感染の関連に関する検討2013

    • Author(s)
      熱田祐一、水野敏秀、武輪能明、築谷朋典、角田幸秀、片桐伸将、大沼健太郎、住倉博仁、藤井 豊、岸本祐一郎、荒川 衛、東郷好美、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 補助人工心臓用ウェアラブル式小型空気圧駆動装置の開発現況2013

    • Author(s)
      住倉博仁、大沼健太郎、本間章彦、妙中義之、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林 宏、片野一夫、小嶋孝一、福井康裕、巽 英介
    • Organizer
      人工心臓と補助循環懇話会学術集会 (41)
    • Place of Presentation
      下高井戸郡山ノ内町
    • Related Report
      2012 Annual Research Report
  • [Presentation] 組織工学的に皮下で作成したStent 付き心臓弁 (Biovalve Stent) の経カテーテル的自家移植の試み2013

    • Author(s)
      武輪能明、中山泰秀、山南将志、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、熱田祐一、水野壮司、松井悠一、神田圭一、田地川 勉、Wieloch R、妙中義之、巽 英介
    • Organizer
      日本再生医療学会学会総会 (12)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 反転型ステント付きバイオバルブの開発:作製方法の確実性の獲得をめざして2013

    • Author(s)
      水野壮司、山南将志、森脇健司、住倉博仁、大沼健太郎、武輪能明、巽 英介、上地正実、中山泰秀
    • Organizer
      日本再生医療学会学会総会 (12)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒトバイオチューブの人工血管としての可能性2013

    • Author(s)
      中山泰秀、武輪能明、金子嘉志、奥村紀子
    • Organizer
      日本再生医療学会学会総会 (12)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rat miniature extracorporeal circulation system for studying the pathophysiology of artificial perfusion2012

    • Author(s)
      Fujii Y, Shirai M, Inamori S, Takewa Y, Tatsumi E, Taenaka Y
    • Organizer
      Annual Meeting of the PSJ (89)
    • Place of Presentation
      松本
    • Year and Date
      2012-03-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 実験的長期VA-ECMO施行時に観察されたヤギの右心室線維化及び肺胞繊維化の病理組織学的研究2012

    • Author(s)
      水野敏秀、片桐伸将、築谷朋典、武輪能明、妙中義之、巽英介
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流型LVAD自己心拍同期変動駆動システム(NHLCS)の冠動脈潅流に対する影響について2012

    • Author(s)
      梅木昭秀、西村隆、武輪能明、安藤政彦、荒川衛、岸本祐一郎、水野敏秀、築谷朋典、許俊鋭、妙中義之、小野稔、巽英介
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流LVAD心電図同期変動回転駆動によるAortic insufficiency予防モードの開発2012

    • Author(s)
      岸本祐一郎、荒川衛、梅木昭秀、安藤政彦、西村隆、武輪能明、西村元延、巽英介
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 体外循環中の病態解明及び各種体外循環ディバイス開発評価のためのラット体外循環モデルの確立2012

    • Author(s)
      藤井豊、白井幹康、武輪能明、巽英介、妙中義之
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流LVADのなす仕事量(Wpump)を用いた心負荷量推定法の提案2012

    • Author(s)
      安藤政彦.西村隆、武輪能明、築谷朋典、水野敏秀、山崎健二、許俊鋭、小野稔、妙中義之、巽英介
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Bridge to recovery目指した定常流型LVADによる心拍同期回転数制御システムの開発2012

    • Author(s)
      荒川衛、武輪能明、西村隆、梅木昭秀、安藤政彦、岸本祐一郎、山崎健二、許俊鋭、安達秀雄、巽英介
    • Organizer
      人工心臓と補助循環懇話会(40)
    • Place of Presentation
      由布
    • Year and Date
      2012-02-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] BTD左心バイパス専用送脱血管の開発と開発システムの動物実験評価2012

    • Author(s)
      武輪能明
    • Organizer
      早期・探索的臨床試験拠点整備事業シーズ紹介セミナー(1)
    • Place of Presentation
      吹田
    • Year and Date
      2012-01-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Optimization of the coronary flow by a novel cardiac cycle-synchronized rotation control model in a continuous-flow LVAD in chronic heart failure model.2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Mizuno T, Tsukiya T, Kyo S, Adachi H, Tatsumi E
    • Organizer
      European Society for Artificial Organs
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of a novel drive mode for preventing aortic insufficiency during continuous-flow LVAD support by electrocardiogram-synchronized rotational speed change.2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Niashimura M, Tatsumi E.
    • Organizer
      European Society for Artificial Organs
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Final Research Report
  • [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use.2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E.
    • Organizer
      International Society for Rotary Blood Pumps
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Final Research Report
  • [Presentation] A novel drive mode of continuous-flow LVAD with cardiac cycle-synchronized rotation control for preventing aortic insufficiency during long-term support, evaluation in chronic heart failure animal model.2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E.
    • Organizer
      International Society for Rotary Blood Pumps
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Final Research Report
  • [Presentation] How to set up rotational speeds in rotary LVADs weaning-estimation of heart work by pump work calculation called "W pump".2012

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Tsukiya T, Mizuno T, Yamazaki K, Kyo S, Ono M, Taenaka Y, Tatsumi E.
    • Organizer
      International Society for Rotary Blood Pumps
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Final Research Report
  • [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) may have more chance to recover the ventricular contractility.2012

    • Author(s)
      Umeki A, Nishimura T, Takewa Y, Ando M, Mizuno T, Tsukiya T, Kyo S, Taenaka Y, Ono M, Tatsumi E.
    • Organizer
      International Society for Rotary Blood Pumps
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Final Research Report
  • [Presentation] Prevention of aortic insufficiency in a continuous flow LVAD by changing rotation speed in synchronization with the cardiac beat.2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Ventricular septum shift by continuous-flow LVAD pumping and its correction by beat to beat rotational speed control.2012

    • Author(s)
      Arakawa M,Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Alternation of LV preload by continuous-flow LVAD with native heart load control system (NHLCS) in chronic heart failure model.2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Kyo S, Adachi H, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use.2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Successful implantation of a completely autologous aortic valve with a stent (Biovalve stent) by transcatheter aortic valve implantation (TAVI)2012

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Sumikura H, Kanda K, Matsui Y, Taenaka Y, Tatsumi E
    • Organizer
      American Heart Association , Scientific Sessions 2012
    • Place of Presentation
      Los Angeles (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of in-body tissue-engineered, completely autologous valve (BIOVALVE)2012

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Kishimoto Y, Arakawa M, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
    • Organizer
      5th biennial conference on Heart valve biology and tissue engineering
    • Place of Presentation
      Myconos island (Greece)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Novel autologous heart valve (Biovalve Stent) for transcatheter aortic valve implantation2012

    • Author(s)
      Takewa Y, Nakayama Y, Matsui Y, Yamanami M, Kanda K, Tatsumi E
    • Organizer
      European Society for Artificial Organs (36)
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Rat miniature extracorporeal circulation system for studying the pathophysiology of artificial perfusion2012

    • Author(s)
      Fujii Y, Shirai M, Inamori S, Takewa Y, Tatsumi E, Taenaka Y
    • Organizer
      Annual Meeting of the PSJ (89)
    • Place of Presentation
      Matsumoto (Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development and animal test of the novel infection-resistant skin-button for long-term VAD support2012

    • Author(s)
      Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
    • Organizer
      International Society for Heart and Lung Transplantation, Annual Meeting & Scientific Sessions (32)
    • Place of Presentation
      Prague (Checo)
    • Related Report
      2012 Annual Research Report
  • [Presentation] A novel miniature CPB model using rat for pathophysiological examination2012

    • Author(s)
      Fujii Y, Shirai M, Inamori S, Takewa Y, Tatsumi E, Taenaka Y
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development and animal test of a novel infection-resistant skin-button for long-term VAD support2012

    • Author(s)
      Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] In-vivo performance study of a durable cardiopulmonary support system consisting of a hydrodynamically levitated centrifugal pump2012

    • Author(s)
      Tsukiya T, Mizuno T, Takewa Y, Osada T, Yamane T, Tatsumi E, Taenaka Y
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Prevention of aortic insufficiency in a continuous flow LVAD by changing rotation speed in synchronization with the cardiac beat2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] In vitro evaluation of a novel autologous aortic valve (BIOVALVE) with a special pulsatile circulation circuit2012

    • Author(s)
      Sumikura H, Nakayama Y, Ohnuma K, Takewa Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development and evaluation of a compact wearable pneumatic drive unit for a ventricular assist device2012

    • Author(s)
      Ohnuma K, Homma A, Sumikura H, Tatsumi E, Takewa Y, Taenaka Y, Mizuno T,Tsukiya T, Katagiri N, Kakuta Y, Mukaibayashi H, Katano K
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Ventricular septum shift by continuous-flow LVAD pumping and its correction by beat to beat rotational speed control2012

    • Author(s)
      Arakawa M,Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Alternation of LV preload by continuous-flow LVAD with native heart load control system (NHLCS) in chronic heart failure model2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Kyo S, Adachi H, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (58)
    • Place of Presentation
      San Francisco (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Electrocardiogram-synchronized rotational speed change mode in rotary pumps could improve pulsatility for long time use2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Kishimoto Y, Umeki A, Ando M, Kyo S, Adachi H, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] A novel drive mode of continuous-flow LVAD with cardiac cycle-synchronized rotation control for preventing aortic insufficiency during long-term support, evaluation in chronic heart failure animal model2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Nishimura M, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] How to set up rotational speeds in rotary LVADs weaning - estimation of heart work by pump work calculation called "W pump"2012

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Tsukiya T, Mizuno T, Yamazaki K, Kyo S, Ono M, Taenaka Y, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) may have more chance to recover the ventricular contractility2012

    • Author(s)
      Umeki A, Nishimura T, Takewa Y, Ando M, Mizuno T, Tsukiya T, Kyo S, Taenaka Y, Ono M, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Preclinical evaluation of a cardiopulmonary support system consisting of the newly-developed centrifugal pump with a unique hydrodynamic bearing2012

    • Author(s)
      Tsukiya T, Mizuno T, Takewa Y, Yamane T, Hoshi H, Okubo T, Osada T, Tatsumi E, Taenaka Y
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development and in vivo evaluation of a novel tissue-compatible inflow cannula for an implantable VAD2012

    • Author(s)
      Miizuno T, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] A small animal extracorporeal circulation model for studying pathophysiology of cardiopulmonary bypass2012

    • Author(s)
      Fujii Y, Shirai M, Takewa Y, Tatsumi E, Taenaka Y
    • Organizer
      International Society for Rotary Blood Pumps (20)
    • Place of Presentation
      Istanbul (turkey)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Optimization of the coronary flow by a novel cardiac cycle-synchronized rotation control model in a continuous-flow LVAD in chronic heart failure model2012

    • Author(s)
      Arakawa M, Takewa Y, Nishimura T, Umeki A, Ando M, Kishimoto Y, Mizuno T, Tsukiya T, Kyo S, Adachi H, Tatsumi E
    • Organizer
      European Society for Artificial Organs (36)
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Annual Research Report
  • [Presentation] In vivo-tissue engineered autologous aortic valved conduits (Biovalves type VII): preparation and revolution2012

    • Author(s)
      Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Akagawa E, Okumura K, Tajikawa T, Kanda K, Taenaka Y, Tatsumi E
    • Organizer
      European Society for Artificial Organs (36)
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of a novel drive mode for preventing aortic insufficiency during continuous-flow LVAD support by electrocardiogram-synchronized rotational speed change2012

    • Author(s)
      Kishimoto Y, Arakawa M, Umeki A, Ando M, Nishimura T, Takewa Y, Niashimura M, Tatsumi E
    • Organizer
      European Society for Artificial Organs (36)
    • Place of Presentation
      Rostock (Germany)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Change of Heart rate variability and correlation with cardiac function during development process of chronic heart failure in large animal model2012

    • Author(s)
      Kishimoto Y, Ohnuma K, Arakawa M, Umeki A, Takewa Y, Nishimura M, Tatsumi E
    • Organizer
      American Heart Association , Scientific Sessions 2012
    • Place of Presentation
      Los Angeles (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] In vitro and in vivo performance of a completely autologous aortic valued conduit (BIOVALVE Type VII) prepared by in body tissue architecture technology using a novel separable mold2012

    • Author(s)
      Nakayama Y, Takewa Y, Sumikura H, Matsui Y, Yamanami M, Kishimoto Y, Arakawa M, Ohnuma K, Mizuno T, Oie T, Kanda K, Tatsumi E
    • Organizer
      American Heart Association , Scientific Sessions 2012
    • Place of Presentation
      Los Angeles (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体内組織形成技術で作成した心臓弁付Conduit (BIOVALVE)の大動脈系自家移植実験2012

    • Author(s)
      山南将志、武輪能明、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、松井悠一、渡辺太治、神田圭一、夜久 均、田地川勉、大場謙吉、妙中義之、巽 英介、中山泰秀
    • Organizer
      日本心臓血管外科学会学術総会 (42)
    • Place of Presentation
      秋田市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 体外循環中の生体反応および体外循環デバイス評価につながる小動物体外循環モデルの構築2012

    • Author(s)
      藤井 豊、白井幹康、武輪能明、築谷朋典、巽 英介、妙中義之
    • Organizer
      日本バイオレオロジー学会年会 (35)
    • Place of Presentation
      新潟市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 患者の体内で自家移植用臓器を作成し、移植後急速な再生組織構築を誘導する『生体内組織形成技術』の開発2012

    • Author(s)
      神田圭一、山南将志、渡辺太治、田地川 努、大場謙吉、武輪能明、巽 英介、上地正実、夜久 均、中山泰秀
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体内組織形成術:自分の移植物を自分の体内で作れる新技術2012

    • Author(s)
      中山泰秀、神田圭一、武輪能明、上地正実、渡辺太治、山南将志
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] バイオバルブ心臓弁の生体外機能・耐久性評価2012

    • Author(s)
      中山泰秀、住倉博仁、大沼健太郎、武輪能明、巽 英介
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] バイオバルブ心臓弁の生体内形成過程のカプセル内視鏡観察2012

    • Author(s)
      中山泰秀、武輪能明、大家智憲、山南将志、神田圭一、松井悠一、田地川 勉、大場謙吉、妙中義之、巽 英介
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 組織工学的に皮下で作成した心臓弁(BIOVALVE)の左心系自家移植による評価2012

    • Author(s)
      武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、藤井 豊、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体内組織形成技術による循環器系再生医療デバイスの開発2012

    • Author(s)
      山南将志、渡辺太治、神田圭一、夜久 均、上地正実、武輪能明、巽 英介、中山泰秀
    • Organizer
      日本再生医療学会総会 (11)
    • Place of Presentation
      横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 大動物慢性心不全モデル作成過程における心拍変動指標の変化2012

    • Author(s)
      岸本祐一郎、大沼健太郎、荒川 衛、梅木昭秀、武輪能明、西村元延、巽 英介
    • Organizer
      日本循環器学会 中国・四国合同地方会 (100)
    • Place of Presentation
      広島市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流LVAD心電図同期変動回転駆動によるAortic insufficiency予防モードの開発2012

    • Author(s)
      岸本祐一郎、荒川 衛、梅木昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
    • Organizer
      日本循環器学会 中国・四国合同地方会 (100)
    • Place of Presentation
      広島市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流LVAD心拍同期回転数制御システムによるAortic insufficiency予防モードの開発-急性心不全モデルにおける検討-2012

    • Author(s)
      岸本祐一郎、荒川 衛、梅木 昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
    • Organizer
      日本胸部外科学会定期学術集会 (65)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流型LVAD自己心拍同期変動システム (NHLCS) の心筋酸素消費量と心収縮力への影響についての考察2012

    • Author(s)
      梅木昭秀、西村 隆、武輪能明、安藤政彦、荒川 衛、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、妙中義之、小野 稔、巽 英介
    • Organizer
      日本胸部外科学会定期学術集会 (65)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 組織工学的に皮下で作成した自家組織大動脈弁 (Biovalve) のTAVIを用いた治療の可能性2012

    • Author(s)
      武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、藤井 豊、松井悠一、神田圭一、夜久 均、田地川 勉、大場謙吉、妙中義之、巽 英介
    • Organizer
      日本胸部外科学会定期学術集会 (65)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工心臓・人工肺の抗血栓性に関する問題点と対策2012

    • Author(s)
      巽 英介、武輪能明、築谷朋典、水野敏秀、妙中義之
    • Organizer
      日本栓子検出と治療学会 (エンボラス学会) (15)
    • Place of Presentation
      豊中市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流型補助人工心臓を用いた自己心拍同期回転数制御システムの合併症予防効果の検討2012

    • Author(s)
      荒川 衛、岸本祐一郎、武輪能明、西村 隆、梅木昭秀、安藤政彦、藤井 豊、住倉博仁、大沼健太郎、東郷好美、熱田祐一、水野敏秀、築谷朋典、許 俊鋭、安達秀雄、巽 英介
    • Organizer
      日本定常流ポンプ研究会2012
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工心臓使用時のデバイス由来感染症防止に有用なスキンボタン・デバイス被覆材の開発2012

    • Author(s)
      水野敏秀、根本 泰、熱田祐一、柳園宜紀、小原大輔、築谷朋典、武輪能明、妙中義之、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 溶血試験血液の一様性と普遍性2012

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、巽 英介、妙中義之
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 水素付加による体外循環時の炎症反応及び臓器障害の抑制効果2012

    • Author(s)
      藤井 豊、白井幹康、武輪能明、巽 英介、妙中義之
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 長期呼吸補助循環システムの開発と性能評価2012

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、星 英男、大久保剛、長田俊幸、山根隆志、巽 英介、妙中義之
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] ジャイロポンプを用いた抗血栓性コーティング心肺補助システムの長期耐久性評価2012

    • Author(s)
      片桐伸将、巽 英介、武輪能明、水野敏秀、築谷朋典、岸本祐一郎、小原大輔、柳園宜紀、妙中義之
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 自己組織からなる TAVI 用 Stent 付き心臓弁 (Biovalve Stent) の開発 : 動物実験評価2012

    • Author(s)
      武輪能明、中山泰秀、岸本祐一郎、荒川 衛、山南将志、住倉博仁、大沼健太郎、熱田祐一、藤井 豊、水野壮司、松井悠一、神田圭一、田地川勉、妙中義之、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] バイオバルブ大動脈弁 ( Type VII ) の開発2012

    • Author(s)
      中山泰秀、武輪能明、松井悠一、岸本祐一郎、荒川 衛、住倉博仁、大沼健太郎、山南将志、水野壮司、田地川勉、神田圭一、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] バイオバルブ心臓弁の拍動流回路を用いた生体外機能・耐久性評価2012

    • Author(s)
      住倉博仁、中山泰秀、武輪能明、大沼健太郎、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] ニプロ社製LVAS施行時における出口部感染防止に優れたセグメント化ポリウレタン製多孔体スキンカフの開発2012

    • Author(s)
      熱田祐一、水野敏秀、武輪能明、築谷朋典、角田幸秀、片桐伸将、大沼健太郎、住倉博仁、藤井 豊、岸本祐一郎、荒川 衛、東郷好美、妙中義之、巽 英介、柳園宜紀、小原大輔
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規開発された動圧浮上型軸流ポンプを用いた埋め込み型補助人工心臓システムの慢性動物実験による in vivo 評価2012

    • Author(s)
      水野敏秀、築谷朋典、大久保剛、長田俊幸、武輪能明、山根隆志、妙中義之、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 定常流型LVAD自己心拍同期変動駆動システム (NHLCS) が心拍出力に与える影響2012

    • Author(s)
      梅木昭秀、西村 隆、武輪能明、安藤政彦、岸本祐一郎、水野敏秀、築谷朋典、許 俊鋭、妙中義之、小野 稔、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] Aortic insufficiency 予防に有効な定常流LVAD心拍同期回転数制御システムを用いた新規駆動法の開発2012

    • Author(s)
      岸本祐一郎、荒川 衛、梅木昭秀、安藤政彦、西村 隆、武輪能明、西村元延、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 大動物慢性心不全モデル作成過程から定常流 LVAD 装着後における心拍変動指標の変化2012

    • Author(s)
      岸本祐一郎、大沼健太郎、荒川 衛、梅木昭秀、水野敏秀、武輪能明、西村元延、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工臓器製品化におけるユーザートレーニングの役割 -体内植込み型左心室補助人工心臓を例に-2012

    • Author(s)
      東郷好美、武輪能明、水野敏秀、妙中義之、山崎健二、西中、知博、牛山博之、小山修一、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] EVAHEARTを用いた自己心拍同期回転数制御システムの心拍数増加に伴う心筋酸素消費量の変化2012

    • Author(s)
      荒川 衛、武輪能明、西村 隆、岸本祐一郎、梅木昭秀、安藤政彦、藤井 豊、住倉博仁、大沼健太郎、熱田祐一、東郷好美、水野敏秀、築谷朋典、許 俊鋭、安達秀雄、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 確率的手法による自己調節的人工心臓制御の試み2012

    • Author(s)
      大沼健太郎、住倉博仁、本間章彦、赤川英毅、武輪能明、水野敏秀、築谷朋典、巽 英介
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 空気駆動式補助人工心臓用流量モニタリングシステムの開発と評価2012

    • Author(s)
      大沼健太郎、本間章彦、住倉博仁、妙中義之、巽 英介、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林 宏、片野一夫、小嶋孝一
    • Organizer
      日本人工臓器学会大会 (50)
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] ジャイロポンプを用いた抗血栓性コーティング ECMO システムの長期耐久性評価2012

    • Author(s)
      片桐伸将、巽 英介、武輪能明、水野敏秀、築谷朋典、小原大輔、柳園宜紀、妙中義之
    • Organizer
      膜型人工肺研究会 (40)
    • Place of Presentation
      足立区
    • Related Report
      2012 Annual Research Report
  • [Presentation] 10年後の VAD 治療を見据えた要素技術開発2012

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、巽 英介
    • Organizer
      日本定常流ポンプ研究会2012
    • Place of Presentation
      福岡市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 心室内形状を考慮した、心拍動下に装着可能な低侵襲性かつ抗血栓性補助循環脱血カニューラの開発2011

    • Author(s)
      武輪能明、片桐伸将、梅木昭秀、岸本祐一郎、藤井豊、住倉博仁、大沼健太郎、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流型LVAD離脱の際、理想的な自己心機能評価方法(Off-Test mode)について2011

    • Author(s)
      梅木昭秀、西村隆、武輪能明、安藤政彦、水野敏秀、築谷朋典、許俊鋭、山崎健二、妙中義之、小野稔、巽英介
    • Organizer
      日本定常流ポンプ研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 非接触軸受を用いた左心補助人工心臓システムの慢性動物実験による生体適合性評価2011

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、大久保剛、長田俊幸、山根隆志、巽英介、妙中義之
    • Organizer
      日本定常流ポンプ研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] ウェアラブル式小型空気駆動装置を用いた全置換型人工心臓システムのin vivo性能評価2011

    • Author(s)
      住倉博仁、本間章彦、大沼健太郎、妙中義之、武輪能明、梅木昭秀、水野敏秀、花田繁、築谷朋典、片桐伸将、藤井豊、角田幸秀、向林宏、片野一夫、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] カプセル内視鏡内臓鋳型を用いた体内組織形成過程のin situ観察2011

    • Author(s)
      中山泰秀、武輪能明、大家智憲、山南将志、松井悠一、田地川勉、大場謙吉、神田圭一、夜久均、巽英介、妙中義之
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 空気駆動式補助人工心臓用流量モニタリングシステムの開発2011

    • Author(s)
      大沼健太郎、本間章彦、住倉博仁、妙中義之、巽英介、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、向林宏、片野一夫
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流補助人工心臓の心拍変動に与える影響2011

    • Author(s)
      岸本祐一郎、大沼健太郎、梅木昭秀、武輪能明、築谷朋典、水野敏秀、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 定常流型LVAD自己心拍同期駆動システム(NHLCS)による冠動脈流量、心筋酸素消費量のコントロールについて2011

    • Author(s)
      梅木昭秀、武輪能明、西村隆、安藤政彦、岸本祐一郎、水野敏秀、築谷朋典、許俊鋭、小野稔、山崎健二、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Wedge Thrombus防止に有用な組織親和性に優れた新規ポリエステルベロア装着脱血カニューレの開発2011

    • Author(s)
      水野敏秀、築谷朋典、長田俊幸、山根隆志、武輪能明、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] ドライブライン感染防止に有用な新規スキンボタンの開発とin vivo評価2011

    • Author(s)
      水野敏秀、根本泰、築谷朋典、武輪能明、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 開口位バイオバルブ人工弁の組立式設計によるストレスフリー摘出(Type VII)2011

    • Author(s)
      松井悠一、山南将志、武輪能明、田地川勉、大場謙吉、神田圭一、夜久均、巽英介、中山泰秀
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 体外循環中の生体反応の評価-ラット体外循環モデルを用いて-2011

    • Author(s)
      藤井豊、白井幹康、稲盛修二、武輪能明、巽英介、妙中義之
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 動圧軸受を利用した次世代型高機能血液ポンプの開発2011

    • Author(s)
      築谷朋典、水野敏秀、武輪能明、山根隆志、大久保剛、長田俊之、白数昭雄、巽英介、妙中義之
    • Organizer
      日本人工臓器学会大会(49)
    • Place of Presentation
      東京
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Successful aortic valve implantation using an in-Body tissue-engineered, completely autologous valved conduit (BIOVALVE) in a goat model2011

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
    • Organizer
      Anerican Heart Association Scientific Sessions 2011
    • Place of Presentation
      オーランド(米国)
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] In-body tissue-engineered and completely autologous aortic valved conduit (BIOVALVE) in a goat model2011

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Hanada S, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Large animal models of heart failure for development of new LVAD therapy : combination method of micro-embolization and rapid pacing can control the degree of heart dysfunction and stabilize the result of model making2011

    • Author(s)
      Umeki A, Takewa Y, Nishimura T, Ando M, Mizuno T, Tsukiya T, Ono M, Kyo S, Taenaka Y, Tatsumi E
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Architecture design of a novel separable mold to obtain autologous tissue heart valves "Biovalves" non-invasively2011

    • Author(s)
      Nakayama Y, Matsui Y, Yamanami M, Takewa Y, Tatsumi E, Taenaka Y, Oie T, Tajikawa T, Ohba K, Kanda K, Yaku H
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Preparation of a completely autologous valved conduit with the open form of trileaflets (type VI BIOVALVE)2011

    • Author(s)
      Yamanami M, Yahata Y, Uechi M, Takewa Y, Shimakawa Y, Matsui Y, Tajikawa T, Ohba K, Kanda K, Yaku H, Tatsumi E, Nakayama Y
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of durable rotary blood pump systems using hydrodynamic bearing technology2011

    • Author(s)
      Tsukiya T, Mizuno T, Takewa Y, Tatsumi E, Okubo T, Osada T, Yamane T, Taenaka Y
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] In vivo evaluation of a wearable pneumatic total artificial heart system with compact drive unit2011

    • Author(s)
      Sumikura H, Homma A, Ohnuma K, Taenaka Y, Takewa Y, Umeki A, Mizuno T, Hanada S, Tsukiya T, Katagiri N, Fujii Y, Kakuta Y, Mukaibayashi H, Katano K, Tatsumi E
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) for bridge to recovery could control the coronary flow and myocardial oxygen consumption in acute heart failure model2011

    • Author(s)
      Nishimura T, Umeki A, Takewa Y, Ando M, Mizuno T, Tsukiya T, Yamazaki K, Ono M, Kyo S, TaenakaY, Tatsumi E
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Investigation of a computational analysis for gaseous transfers between the blood layer and the gas layer in a segment of a hollow fiber bundle of an oxygenator2011

    • Author(s)
      Katagiri N, Funakubo A, Tsukiya T, Tatsumi E, Takewa Y, Mizuno T, Taenaka Y, Fukui Y
    • Organizer
      Joint ESAO-IFAO Congress (4)
    • Place of Presentation
      ポルト(ポルトガル)
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Ideal Controlling mode (Off test mode) for evaluating the native heart function in time of wearing the LVAD : Controlling the power of continuous-flow LVAD to decrease the reversal pump flow in diastolic phase2011

    • Author(s)
      Umeki A, Takewa Y, Nishimura T, Ando M, Ono M, Kyo S, Tatsumi E
    • Organizer
      Congress of the International Society for Rotary Blood Pumps (19)
    • Place of Presentation
      ルイビル(米国)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development and in vivo evaluation of novel infection-resistant skin-button for an implantable axial flow VAD system2011

    • Author(s)
      Mizuno T, Nemoto Y, Tsukiya T, Takewa Y, Taenaka Y, Tatsumi E
    • Organizer
      Congress of the International Society for Rotary Blood Pumps (19)
    • Place of Presentation
      ルイビル(米国)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Recent progress in the development of axial flow pump implantable VAD system-in vivo performance testing2011

    • Author(s)
      Tsukiya T, Mizuno T, Takewa Y, Osada T, Yamane T, Tatsumi E, Taenaka Y
    • Organizer
      Congress of the International Society for Rotary Blood Pumps (19)
    • Place of Presentation
      ルイビル(米国)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of an in-body tissue-engineered autologous aortic bioprosthesis2011

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K, Taenaka Y, Tatsumi E
    • Organizer
      Joint meeting of the society for heart valve disease & heart valve society of America
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2011-06-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] In vivo evaluation of an in-body tissue-engineered and completely autologous aortic valved conduit (bio-valve) in a goat model2011

    • Author(s)
      Takewa Y, Nakayama Y, Yamanami M, Hanada S, Umeki A, Matsui Y, Kanda K, Yaku H, Tajikawa T, Ohba K
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Deposition transfection technology using a homopolymer with both thermoresponsive and cationic characters for cardiac gene therapy2011

    • Author(s)
      Zhou YM, Takewa Y, Iwai R, Kusakabe S, Kanzaki K, Taenaka Y, Tatsumi E, Nakayama Y
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] The continuous-flow LVAD with native heart load control system (NHLCS) for bridge to recovery could control myocardial consumption of oxygen in acute heart failure model2011

    • Author(s)
      Nishimura T, Umeki A, Takewa Y, Ando M, Tsukiya T, Mizuno T, Kyo S, Ono M, Yamazaki K, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] The change of coronary by controlling the power of continuous-flow left ventricular assist device in acute heart failure : Counterpulse drive mode can increase the coronary flow2011

    • Author(s)
      Umeki A, Takewa Y, Nishimura T, Ando M, Mizuno T, Tsukiya T, Ono M, Kyo S, Yamazaki K, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development and in vivo test of a new VAD system with hydrodynamic ally-levitated axial flow turbo pump2011

    • Author(s)
      Mizuno T, Tsukiya T, Osada T, Yamane T, Takewa Y, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Flow rate monitoring for a pneumatic VAD using the driveline air mass flow2011

    • Author(s)
      Ohnuma K, Sumikura H, Homma A, Taenaka Y, Takewa Y, Mizuno T, Tsukiya T, Katagiri N, Mukaibayashi H, Katano K
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of a novel skin-button for preventing the driveline infection of an implantable VAD system2011

    • Author(s)
      Mizuno T, Tsukiya T, Nemoto Y, Takewa Y, Taeneka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Blood compatibility testing of the centrifugal blood pump with the hydrodynamic bearing system2011

    • Author(s)
      Tsukiya T, Mizuno T, Takewa Y, Tasumi E, Taenaka Y, Hoshi H, Okubo T, Osada T, Yamane T, Shirasu A
    • Organizer
      American Society for Artificial Internal Organs (57)
    • Place of Presentation
      ワシントンDC(米国)
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血液ガス反応を伴う物質移動の数値解析手法を用いた人工肺内の酸素・炭酸ガス移動量推定に関する検討2011

    • Author(s)
      片桐伸将、舟久保昭夫, 築谷朋典, 巽英介, 水野敏秀, 武輪能明, 妙中義之, 福井康裕
    • Organizer
      日本バイオレオロジー学会年会(34)
    • Place of Presentation
      吹田
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 組織工学的に皮下で作製した自己組織由来心臓弁付きConduit(Biovalve)の開発2011

    • Author(s)
      武輪能明、中山泰秀、山並将志、花田繁、梅木昭秀、松井悠一、神田圭一、夜久均、田地川勉、大場謙吉、妙中義之、巽英介
    • Organizer
      日本炎症・再生医学会(32)
    • Place of Presentation
      京都
    • Year and Date
      2011-06-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 完全自己組織からなる心臓弁様組織体バイオバルブ(Type VI)の開発:開口形状での弁形成による弁機能の向上2011

    • Author(s)
      山並将志、矢羽田侑希、上地正実、武輪能明、島川祐司、松川悠一、田地川勉、大場謙吉、神田圭一、夜久均、巽英介、中山泰秀
    • Organizer
      日本炎症・再生医学会(32)
    • Place of Presentation
      京都
    • Year and Date
      2011-06-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] バイオバルブの開発:作成用鋳型の変遷2011

    • Author(s)
      中山泰秀、松井悠一、山並将志、田地川勉、大場謙吉、神田圭一、夜久均、上地正実、武輪能明、巽英介
    • Organizer
      日本炎症・再生医学会(32)
    • Place of Presentation
      京都
    • Year and Date
      2011-06-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] The continuous flow LVAD with native heart load control system (NHLCS) for bridge to recovery could control the coronary flow and myocardial oxygen consumption in acute heart failure model.2011

    • Author(s)
      Nishimura T, Umeki A, Takewa Y, Ando M, Mizuno T, Tsukiya T, Yamazaki K, Ono M, Kyo S, Taenaka Y, Tatsumi E.
    • Organizer
      Joint ESAO-IFAO Congress
    • Place of Presentation
      Porto (Portugal)
    • Related Report
      2012 Final Research Report
  • [Presentation] Ideal Controlling mode (Off test mode) for evaluating the native heart function in time of wearing the LVAD : Controlling the power of continuous flow LVAD to decrease the reversal pump flow in diastolic phase.2011

    • Author(s)
      Umeki A, Takewa Y, Nishimura T, Ando M, Ono M, Kyo S, Tatsumi E.
    • Organizer
      Congress of the International Society for Rotary Blood Pumps
    • Place of Presentation
      Louisville (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] The change of coronary flow by controlling the power of continuous-flow left ventricular assist device in acute heart failure : Counterpulse drive mode can increase the coronary flow.2011

    • Author(s)
      Umeki A, Takewa Y, Nishimura T, Ando M, Mizuno T, Tsukiya T, Ono M, Kyo S, Yamazaki K, Taenaka Y, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      Washington D.C. (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] The continuous-flow LVAD with native heart load control system(NHLCS) for bridge to recovery could control myocardial consumption of oxygen in acute heart failure model.2011

    • Author(s)
      Nishimura T, Umeki A, Takewa Y, Ando M, Tsukiya T, Mizuno T, Kyo S, Ono M, Yamazaki K, Taenaka Y, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      Washington D.C. (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] 超耐久性小児用ECMOの研究開発を臨床応用2010

    • Author(s)
      齋藤友宏、巽英介、片桐伸将、武輪能明、水野敏秀、築谷朋典、林輝之、吉田幸太郎、妙中義之
    • Organizer
      膜型人工肺研究会(39)
    • Place of Presentation
      仙台市
    • Year and Date
      2010-11-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 空気駆動式人工心臓の流量推定に関する検討2010

    • Author(s)
      大沼健太郎、本間章彦、住倉博仁、妙中義之、巽英介、赤川英毅、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、下崎勇生、向林宏、片野一夫
    • Organizer
      リニアドライブ研究会
    • Place of Presentation
      仙台市
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pulsatility can be created in rotary pumps by ECG-synchronized rotation speed change mode.2010

    • Author(s)
      ndo M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Ono M, Tatsumi E.
    • Organizer
      International Society for Rotary Blood Pumps
    • Related Report
      2012 Final Research Report
  • [Presentation] Full bypass by a continuous-flow left ventricular assist device can diminish coronary flow in normal goat hearts.2010

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Ono M, Tatsumi E.
    • Organizer
      European Society for Artificial Organs
    • Related Report
      2012 Final Research Report
  • [Presentation] A novel counterpulse drive mode in a continuous-flow left ventricular assist device effect on coronary circulation.2010

    • Author(s)
      Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Taenaka Y, Tatsumi E.
    • Organizer
      American Society for Artificial Internal Organs
    • Place of Presentation
      Baltimore (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of an ultra-durable heparin-free ECMO system and its clinical application to pediatric and adult patients In Japan2010

    • Author(s)
      Tatsumi E, Katagiri N, Takewa Y, Mizuno T, Tsukiya T, Homma A, Taenaka Y, Hayashi T, Yagihara T
    • Organizer
      International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion (5)
    • Place of Presentation
      Boston
    • Related Report
      2010 Annual Research Report
  • [Presentation] The ultra-durable heparin-free pediatric and adult ECMO systems and its clinical application in Japan2010

    • Author(s)
      Katagiri N, Tatsumi E, Takewa Y, Mizuno T, Tsukiya T, Homma A, Hayashi T, Yoshida K, Funakubo A, Fukui Y, Takewa Y
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Heart rate variability in ventricular assist device animals in view of the mathematical models2010

    • Author(s)
      Akagawa E, Takewa Y, Sumikura H, Ohnuma K, Kakuta Y, Homma A, Hanada S, Zhou YM, Mizuno T, Tsukiya, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Flow rate estimation for a pneumatic artificial heart using the driveline air mass flow2010

    • Author(s)
      Ohnuma K, Homma A, Taenaka Y, Tatsumi E, Sumikura H, Akagawa E, Takewa Y, Mizuno T, Tsukiya T, Katagiri, Kakuta Y, Shimosaki I, Mukaibayashi H, Katano K.
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of a novel inflow cannula for less invasive and antithrombogenic LVAD support2010

    • Author(s)
      Takewa Y, Tatsumi E, Homma A, Tsukiya T, Mizuno T, Taenaka Y
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of selective renal artery perfusion with extracorporeal circuit on renal function under acute cardio-renal syndrome2010

    • Author(s)
      Hanada S, Takewa Y, Katagiri N, Akagawa E, Homma A, Mizuno T, Tsukiya T, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of a wearable pneumatic total artificial heart system with an ultra compact drive unit2010

    • Author(s)
      Sumikura H, Homma A, Taenaka Y, Tatsumi E, Ohmuma K, Akagawa E, Takewa Y, Mizuno T, Tsukiya T, Katagiri N, Kakuta Y, Shimosaki I, Mukaibayashi H, Katano K
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] A novel counterpulse drive mode in a continuous-flow left ventricular assist device effect on coronary circulation2010

    • Author(s)
      Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, Taenaka Y, Tatsumi E
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of an ultra-compact pneumatic pressure generation system to drive a pneumatic blood pump for VAD and TAH2010

    • Author(s)
      Homma A, Taenaka Y, Tatsumi E, Sumikura H, Ohnuma K, Akagawa E, Takewa Y, Mizuno T, Tsukiya T, Katagiri N, Kakuta Y, Shimosaki I, Mukaibayashi H, Katano K
    • Organizer
      American Society for Artificial Internal Organs (56)
    • Place of Presentation
      Baltimore
    • Related Report
      2010 Annual Research Report
  • [Presentation] Full bypass by a continuous-flow left ventricular assist device can diminish coronary flow in normal goat hearts2010

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Minoru O, Tatsumi E
    • Organizer
      European Society for Artificial Organs (37)
    • Place of Presentation
      Skopje
    • Related Report
      2010 Annual Research Report
  • [Presentation] In vivo test of a novel inflow cannula for less invasive and antithrombogenic LVAD support2010

    • Author(s)
      Takewa Y, Tatsumi E, Katagiri N, Mizuno T, Tsukiya T, Taenaka Y
    • Organizer
      European Society for Artificial Organs (37)
    • Place of Presentation
      Skopje
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pulsatility can be created in rotary pumps by ECG synchronized rotation speed change mode2010

    • Author(s)
      Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Minoru O, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (18)
    • Place of Presentation
      Berlin
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development and hydrodynamic evaluation of a novel inflow cannula in a mechanical circulatory supporter for bridge to decision2010

    • Author(s)
      Sumikura H, Tsukiya T, Toda K, Takewa Y, Watanabe F, Taenaka Y, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (18)
    • Place of Presentation
      Berlin
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of a novel inflow cannula, 'Lantern cannula' for simple and less invasive continuous flow LVAD support2010

    • Author(s)
      Takewa Y, Toda K, Sumikura H, Tsukiya T, Watanabe F, Taenaka Y, Tatsumi E
    • Organizer
      International Society for Rotary Blood Pumps (18)
    • Place of Presentation
      Berlin
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of an ultra-durable heparin-free extracorporeal membrane oxygenation system and its clinical use for pediatric patients2010

    • Author(s)
      Saito T, Tatsumi E, Katagiri N, Takewa Y, Mizuno T, Hayashi T, Taenaka Y
    • Organizer
      International Society for Rotary Blood Pumps (18)
    • Place of Presentation
      Berlin
    • Related Report
      2010 Annual Research Report
  • [Presentation] 空気駆動式ウェアラブル全置換型人工心臓用小型駆動装置に関する基礎的検討2010

    • Author(s)
      住倉博仁、本間章彦、妙中義之、巽英介、大沼健太郎、赤川英毅、李桓成、武輪能明、水野敏秀、築谷朋典、片桐伸将、角田幸秀、下崎勇生、向林宏、片野一夫
    • Organizer
      日本機械学会(22)
    • Place of Presentation
      北九州市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 長期使用を目指した次世代型人工肺の開発研究と臨床応用2010

    • Author(s)
      片桐伸将、巽英介、武輪能明、水野敏秀、築谷朋典、林輝行、吉田幸太郎、舟久保昭夫、福井康裕、妙中義之
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新小児補助循環システム開発におけるシーズとニーズの融合2010

    • Author(s)
      林輝行、巽英介、吉田幸太郎、片桐伸将、水野敏秀、武輪能明、鍵崎康治、市川肇、八木原俊克
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 生体内組織形成技術を用いた循環器系再生医療技術の開発2010

    • Author(s)
      山南将志、上地正実、神田圭一、渡辺太治、坂井修、矢羽田侑希、藤原めぐみ、河野正太、植田初江、大家智憲、松井悠一、田地川勉、大場謙吉、武輪能明、周粤、巽英介、夜久均、中山泰秀
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新しく開発したLantern Cannulaの流れ解析ならびに圧力損失性能評価2010

    • Author(s)
      築谷朋典、住倉博仁、大沼健太郎、武輪能明、巽英介、妙中義之、戸田宏一、笹川満夫、渡邉文和、宇川純一
    • Organizer
      日本人工臓器学会大会(48)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 定常流離VAD脱評価のための新しい駆動モードの開発2010

    • Author(s)
      安藤政彦、西村隆、武輪能明、山崎健二、許俊鋭、小野稔、築谷朋典、水野敏秀、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 左心補助循環を簡便かつ非侵襲的に施行する左室心尖脱血管Lantern cannulaの開発2010

    • Author(s)
      武輪能明、戸田宏一、齋藤友宏、笹川満夫、渡邉文和、宇川純一、築谷朋典、住倉博仁、大沼健太郎、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗感染性スキンパッドを装備した次世代型補助人工心臓システムの慢性動物実験2010

    • Author(s)
      水野敏秀、築谷朋典、根本泰、大久保剛、長田俊幸、山根隆志、武輪能明、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 急性心腎症候群における最適な腎保護を目指して 補助循環手法を応用した腎動脈選択的な血液灌流法と薬剤注入法の検討2010

    • Author(s)
      花田繁、武輪能明、齋藤友宏、片桐伸将、角田幸秀、水野敏秀、築谷朋典、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 実験的長期VA-ECMO施行時に観察された右心室線維化及び肺胞線維化の病理組織学的研究2010

    • Author(s)
      水野敏秀、片桐伸将、林輝行、武輪能明、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] 組織工学的に皮下で作製した心臓弁付きConduit(Biovalve)の大動脈系自家移植による性能評価2010

    • Author(s)
      武輪能明、中山泰秀、山南将志、花田徹、安藤政彦、齋藤友宏、松井悠一、神田圭一、夜久均、田地川勉、大場謙吉、妙中義之、巽英介
    • Organizer
      日本人工臓器学会大会(48)
    • Place of Presentation
      仙台市
    • Related Report
      2010 Annual Research Report
  • [Presentation] DEVELOPMENT OF CARDIAC GENE THERAPY FOR REFRACTORY HEART FAILURE2009

    • Author(s)
      Y.Takewa, Y.Nakayama, Y-M.Zhou, G-X.Zhang, M.Takaki, Y.Nemoto, Y.Taenaka, E.Tatsumi.
    • Organizer
      European Society for Artificial Organs(ESAO)
    • Place of Presentation
      コンピエーヌ(フランス)
    • Year and Date
      2009-09-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] In vivo evaluation of a novel nano-structured vector for effective cardiacgene transfer2009

    • Author(s)
      Y.Takewa, Y.Nakayama, Y-M.Zhou, G-X.Zhang, M.Takaki, Y.Nemoto, Y.Taenaka, E.Tatsumi.
    • Organizer
      American Society for Artificial Internal Organs(ASAIO)
    • Place of Presentation
      ダラス(米国)
    • Year and Date
      2009-05-30
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2019-07-29  

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