Elucidation brain functional network of by temporal and spatial correlation analysis of ECoG and application for brain-machine interface
| Project/Area Number |
21390406
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Keywords | 機能脳神経外科学 / 脳機能画像 / 脳皮質電位 / 認知機能 / 信号解読 / Classification / Decoding / 機能MRI / Tractography / 脳磁図 / 時間-周波数解析 / 言語 / 高次脳機能 |
|---|
| Research Abstract |
For careful interpretation of spatial and temporal changes of electrocorticogram (ECoG) with semantic tasks, we developed a software to visualize semantic-ECoG dynamics on individual brain. Twenty patients underwent implantation of subdural electrodes (more than 80 channels) bilaterally for diagnostic purpose of intractable epilepsy. Semantic-ECoG was recorded with word, figure and face recognition and memory tasks. The ECoG raw data was processed by averaging and time-frequency analysis and the functional profiles were projected on individual brain surface. Acquired ECoG was classified by Support Vector Machine and Sparse Logistic Regression to decode brain signals. Because of variations of electrode locations, we normalized the ECoG elecrtodes using SPM8. The basal temporal-occipital cortex was activated within 250 msec after visual object presentations. Face stimulation evoked significantly higher ECoG amplitudes than other stimuli. The hipocumpus was dominantly activated than other brain areas by the memory task. Prediction rate od ECoG-classification reached 90%, which was sufficient for clinical use. Semantic-ECoG is a powerful technique to detect and decode the human brain functions.
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Report
(4 results)
Research Products
(101 results)
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[Journal Article] Hydrocephalus due to diffuse villous hyperplasia of the choroid plexus-case report2011
Author(s)
Anei R, Hayashi Y, Hiroshima S, Mitsui N, Orimoto R, Uemori G, Saito M, Sato M, Wada H, Hodozuka A, Kamada K
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Journal Title
Neuro Med Chir (Tokyo)
Volume: 51(6)
Pages: 437-441
NAID
Related Report
Peer Reviewed
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[Journal Article] Integration of Corticospinal Tractography Reduces Motor Complications After Radiosurgery2011
Author(s)
Koga T, Shin M, Maruyama K, Kamada K, Ota T, Itoh D, Kunii N, Ino K, Aoki S, Masutani Y, Igaki H, Onoe T, Saito N
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Journal Title
Int J Radiat Oncol Biol Phys
Volume: (on line)
Issue: 1
Pages: 1-5
DOI
Related Report
Peer Reviewed
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[Presentation] 脳機能温存手術2011
Author(s)
鎌田恭輔
Organizer
第3回福岡脳神経先端治療研究会「招待講演」
Place of Presentation
福岡市
Year and Date
2011-04-22
Related Report
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[Presentation] 脳機能温存手術2011
Author(s)
鎌田恭輔
Organizer
第3回福岡脳神経先端治療研究会
Place of Presentation
福岡市(招待講演)
Year and Date
2011-04-22
Related Report
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