| Co-Investigator(Kenkyū-buntansha) |
JITO Junya 滋賀医科大学, 医学部, 助教 (50534161)
NISHIMURA Masaki 京都大学, 医学研究科, 助教 (60452348)
YOKOI Toshihiro 滋賀医科大学, 医学部, 助教 (20573182)
INUBUSHI Toshiro 滋賀医科大学, MR医学総合研究センター, 教授 (20213142)
MORIKAWA Shigehiro 滋賀医科大学, 医学部, 教授 (60220042)
|
|---|
| Budget Amount *help |
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2011: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2010: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2009: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
|
|---|
| Research Abstract |
In order to elucidate the mechanisms of cerebral aneurysmal development, growth, rupture, we conducted molecular an histological analyses in induced aneurismal models of rats and monkeys. Induced aneurysms were successfully checked using 7T-MRA and the administration of statins, TNF-αinhibitors suppressed the development of cerebral aneurysms by inhibiting inflammatory processes.
|
