| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2011: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2010: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2009: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Research Abstract |
We succeeded in developing techniques for effective internalization of quantum-dots(Q-dots) to mesenchymal stem cells(MSCs). We examined in vitro and in vivo effects of the internalization of Q-dots to MSCs, with using osteogenic, adipogenic, chondrogenic induction. In vitro results suggested negligible effect on each differentiation by the internalization, in vivo results indicated a long term tracking observation for over 8 weeks for bone regeneration model and over 24 weeks for cartilage regeneration model.
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