Investigation of uterine parameter to evaluate uterine receptivity

• Project/Area Number: 21390453
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Obstetrics and gynecology
• Research Institution: Osaka University
• Principal Investigator: KIMURA Tadashi 大阪大学, 医学系・研究科, 教授 (90240845)
• Co-Investigator(Kenkyū-buntansha): NAKAMURA Hitomi 大阪大学, 医学部附属病院, 特任研究員 (80467571) ; HOSONO Takayoshi 大阪電気通信大学, 医療福祉工学科, 教授 (60294104) ; TSUTSUI Tateki 大阪大学, 医学系・研究科, 講師 (00294075) ; KOYAMA Shinsuke 大阪大学, 医学系・研究科, 助教 (30528005)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000); Fiscal Year 2011: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2010: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2009: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
• Keywords: 生殖医学 / 着床 / 子宮 / 不妊症 / 妊娠高血圧症候群 / preterm premature rapture of membrane (pPROM) / intrauterine qrowth restriction (IUGR) / reterm premature rapture of membrane (pPROM) / intrauterine growth restiriction (IUGR) / 血管透過性 / インピーダンス / pH

Research Abstract

Implantation is a key process for pregnancy. It is considered that abnormal implantation, which is occurred at the early stage of pregnancy, is a cause of not only infertility and also pregnancy related conditions and complications. We hypothesized that if we can assess implantation in real time, it could be useful for the treatment of infertility and pregnancy related conditions and complications. We investigated a new parameter to evaluate uterine receptivity using our mouse model.

Research Products

• [Journal Article] Reliable predictors of neonatal immune thrombocytopenia in pregnant women with idiopathic thrombocytopenic purpura (2012)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Kumasawa, K., Tsutsui, T., Kimura, T
  • Journal Title: Am J Hematol Volume: 87(1) Pages: 15-21
  • Peer Reviewed
• [Journal Article] Macrophages regulate expression of alpha1, 2 fucosyltransferase genes in human endometrial epithelial cells (2012)
  • Author(s): Nakamura, H., Jasper, M. J., Hull. M. L. Aplin, J. D., Robertson. S. A
  • Journal Title: Mol Hum Reprod Volume: 18(4) Pages: 204-215
  • Peer Reviewed
• [Journal Article] Central aortic blood pressure and Augmentation index during normal pregnancy (2012)
  • Author(s): Fujime, M., Tomimatsu, T., Okaue, Y., Koyama, S., Kanagawa, T., Taniguchi, T., Kimura, T.
  • Journal Title: Hypertens Res Volume: (In press)
  • NAID: 10030956198
  • Peer Reviewed
• [Journal Article] Ballon tamponade during cesarean section is useful for severe post-partum hemorrhage due to placenta previ (2012)
  • Author(s): Ishii, T., Sawada, K., Koyama, S., Isobe, A., Wakabayashi, A., Takiuchi, T., Kanagawa, T., Tomimatsu., T., Ogita, K., Kimura, T.
  • Journal Title: Obstet Gynaecol Res Volume: 38 Pages: 102-107
  • Peer Reviewed
• [Journal Article] Macrophages regulate expression of alpha1,2 fucosyltransferase genes in human endometrial epithelial cells (2012)
  • Author(s): Nakamura, H., Jasper, M.J., Hull. M.L.Aplin, J.D., Robertson. S.A.
  • Journal Title: Mol Hum Reprod Volume: 18(4) Pages: 204-215
  • Peer Reviewed
• [Journal Article] Pravastain induces placental growth factor(PGF) and ameliorates preecl ampsia in a mouse model (2011)
  • Author(s): Kumasawa, K., Ikawa, M., Kidoya, H., Kasuwa, H., Saito, F., Morioka, Y., Takakura, N., Kimura, T., Okabe, M
  • Journal Title: Proc Natl Acad Sci USA Volume: 108(4) Pages: 1451-1455
  • Peer Reviewed
• [Journal Article] Successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor : the first case report in Japan (2011)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Daimon, E., Kimura, T
  • Journal Title: J Obstet Gynaecol Res Volume: 37 Pages: 1711-1716
  • Peer Reviewed
• [Journal Article] The amnioscope strikes back as auseful device for pinhole amnitomy in the management of polyhydramnios (2011)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Tsutsui, T., Kimura, T.
  • Journal Title: American Jouinal of Perinatology Reports Volume: 1 Pages: 99-104
  • Peer Reviewed
• [Journal Article] Effects of 4-Hydroxy-2-Nonenal, a Major Lipid Perosidation-Derived Aldehude, and N-Acetylcysteine on the Cyclooxygenase-2 Expression in Human Uterine Myometrium (2011)
  • Author(s): Temma-Asano, K., Tskitshviti, E., Kanagawa, T., Tomimatsu, T., Tsutsui, T., Kimura, T.
  • Journal Title: Gynecol Obstet Invest Volume: 72 Pages: 37-42
  • Peer Reviewed
• [Journal Article] Metastatic mucinous adenocarcinoma of the ovary is characterized by advanced patient age, small tumor size, and elevated serum CA 125 (2011)
  • Author(s): Maeda-Taniguchi, M., Ueda, Y., Miyake, T., Kimura, Toshihiro., Yoshino, K., Fujita, M., Wasada, T., Ohashi, H., Morii, E., Enomoto, T., Kimura, T.
  • Journal Title: Gynecol obstet Invest Volume: 72 Pages: 196-202
  • Peer Reviewed
• [Journal Article] A successful case of abdominal radical trachelectomy for cervical cancer during pregnancy (2011)
  • Author(s): Enomoto, T., Yoshino, K., Fujita, M., Miyoshi, Y., Ueda, Y., Koyama, S., Kimura, Toshihiro., Tomimatsu, T., Kimura, T.
  • Journal Title: Eur J Obstet Gynecol Reprod Biol Volume: 158 Pages: 365-366
  • Peer Reviewed
• [Journal Article] Two multipotential transcription factor, NF-kappaB and Stat-3, play critical and hierarchal roles for implantation (2010)
  • Author(s): Kimura, T., Ogita, K., Kumasawa, K., Koyama, S., Tsutsui, T., Nakamura, H
  • Journal Title: Indian Journal of Physiology and Pharmacology Volume: 54(5) Pages: 27-32
  • Peer Reviewed
• [Journal Article] Two multipotential transcription factor, NF-kappaB and Stat-3, play critical and hierarchalroles for implantation (2010)
  • Author(s): Kimura, T., Ogita, K., Kumasawa, K., Koyama, S., Tsutsui, T., Nakamura, H.
  • Journal Title: Indian Journal of Physiology and Pharmacology Volume: 54(5) Pages: 27-32
  • Peer Reviewed
• [Journal Article] Prenatal diagnosis of polysplenia syndrome associated with increased nuchal translucency (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Morimoto, A., Kimura, T.
  • Journal Title: Prenat Diagn Volume: 30(10) Pages: 1005-1006
  • Peer Reviewed
• [Journal Article] Cervical insufficiency following cesarean delivery after prolonged second stage of labor : experiences of two cases (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Sawada, K., Tsutsui, T., Kimura, T.
  • Journal Title: J Obstet Gynaecol Res Volume: 36(2) Pages: 411-413
  • NAID: 10031121630
  • Peer Reviewed
• [Journal Article] Spinal subarachnoid hematoma following spinal anesthesia in a patient with HELLP syndrome (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Sawada, K., Tsutsui, T., Kimura, T., Chang, YS., Wasada, K., Imai, S., Murata, Y.
  • Journal Title: Int J Obstet Anesth Volume: 19(1) Pages: 87-91
  • Peer Reviewed
• [Journal Article] Prenatal diagnosis of fetal intracranial hemorrhage in pregnancy complicated by idiopathic thrombocytopenic purpura (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Sawada, K., Kanagawa, T., Isobe, A., Taniguchi, Y., Wada, T., Kimura, T., Arahori, H., Kitabatake, Y., Wada, K.
  • Journal Title: Prenat Diagn Volume: 30(5) Pages: 489-491
  • Peer Reviewed
• [Journal Article] Pseudomyxoma peritonei originating from colorectal cancer during pregnancy. (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Sawada, K., Kanagawa, T., Tsutsui, T., Kimura, T.
  • Journal Title: J Obstet Gynaecol Res Volume: 37(3) Pages: 254-258
  • Peer Reviewed
• [Journal Article] Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus. (2010)
  • Author(s): Tskitishvili, E., Nakamura, H., Kinugasa-Taniguchi, Y., Kanagawa, T., Kimura, T., Tomimatsu, T., Shimoya, K
  • Journal Title: Am J Reprod Immunol Volume: 63(2) Pages: 137-143
  • Peer Reviewed
• [Journal Article] 妊娠子宮局所におけるマクロファージの役割 (2010)
  • Author(s): 中村仁美, 木村正
  • Journal Title: 医学のあゆみ Volume: 233(2) Pages: 141-145
  • Peer Reviewed
• [Journal Article] 前置胎盤 (2010)
  • Author(s): 瀧内剛, 木村正
  • Journal Title: 産婦人科治療 Volume: 100 Pages: 217-226
  • Peer Reviewed
• [Journal Article] 卵巣予備能の評価-AMHを中心として- (2010)
  • Author(s): 筒井建紀
  • Journal Title: 産婦の進歩 Volume: 62(2) Pages: 154-156
  • NAID: 130000308260
  • Peer Reviewed
• [Journal Article] 妊娠高血圧症候群の病態解明-分子機構を中心に-着床障害モデルからみた妊娠高血圧症候群 (2010)
  • Author(s): 香山晋輔, 中村仁美, 張慶, 田畑知沙, 筒井建紀, 木村正
  • Journal Title: 産婦人科の実際 Volume: 59(7) Pages: 1035-1042
  • Peer Reviewed
• [Journal Article] 妊娠とB型およびC型ウイルス性肝炎 (2010)
  • Author(s): 香山晋輔, 金川武司, 冨松拓治, 木村正
  • Journal Title: 別冊日本臨床 新領域別症候群シリーズNo13 肝・胆道系症候群(第2版)-その他の肝道系疾患を含めて- Volume: 13 Pages: 549-553
  • Peer Reviewed
• [Journal Article] Concurrent weekly nedaplatin, external beam radiotherapy and high-dose rate brachytherapy in patients with FIGO stage IIIB cervical cancer : A comparison with a cohort treated by radiotheraphy alone (2010)
  • Author(s): Mabuchi, S., Ugaki, H., Isohashi, F., Yoshioka, Y., Temma, K., Yoda-Hashimoto, N., Takeda, T., Yamamoto, T., Yoshino, K., Nakajima, R., Kuragaki, C., Morishige, K., Enomoto, T., Inoue, T., Kimura, T.
  • Journal Title: Gynecologic and Obstetric Investigation Volume: 69 Pages: 224-232
  • Peer Reviewed
• [Journal Article] Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus. (2010)
  • Author(s): Tskitishvili, E., Nakamura, H., Kinugasa-Taniguchi, Y., Kanagawa, T., Kimura, T., Tomimatsu, T., Shimoya, K.
  • Journal Title: Int J Gynecol Cancer. Volume: 63 Pages: 137-143
  • Peer Reviewed
• [Journal Article] Spinal subarachnoid hematoma following spinal anesthesia in a patient with HELLP syndrome. (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Sawada, K., Tsutsui, T., Kimura, T., Chang, YS., Wasada, K., Imai, S., Murata, Y.
  • Journal Title: Int J Obstet Anesth. Volume: 19 Pages: 87-91
  • Peer Reviewed
• [Journal Article] Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells. (2010)
  • Author(s): Tskitishvili, E., Sharentuya, N., Temma-Asano, K., Mimura, K., Kinugasa-Taniguchi, Y., Kanagawa, T., Fukuda, H., Kimura, T., Tomimatsu, T., Shimoya, K.
  • Journal Title: Mol Hum Reprod. Volume: 16 Pages: 188-199
  • Peer Reviewed
• [Journal Article] A case of complete hydatidiform mole with co-existent fetus ; conclusive diagnosis of androgenesis of the molar placenta by variation of paternal acrocentric short arm (2010)
  • Author(s): Koyama, S., Tomimatsu, T., Sawada, K., Kanagawa, T., Isobe, A., Kinugasa, Y., Tsutsui, T., Kimura T.
  • Journal Title: America Journal of Perinatology Volume: 27 Pages: 143-149
  • Peer Reviewed
• [Journal Article] 妊娠子宮局所におけるマクロファージの役割 (2010)
  • Author(s): 中村仁美、木村正
  • Journal Title: 医学のあゆみ Volume: 233巻(In press)
  • Peer Reviewed
• [Journal Article] Spinal subarachnoid hematoma following spinal anesthesia in a patient with HELLP syndrome (2009)
  • Author(s): Koyama, S., Tomimatsu, T., Kanagawa, T., Sawada, K., Tsutsui, T., Kimura, T., Chang YS., Wasada. K., Imai, S., Murata, Y.
  • Journal Title: Int Obestet Anesth Volume: 19 Pages: 87-91
  • Peer Reviewed
• [Journal Article] Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice (2009)
  • Author(s): Yoshida, M., Takayanagi, Y., Inoue, K., Kimura, T.,, Young, L.J, Onaka, T., Nishimori, K.
  • Journal Title: Journal of Neuroscience Volume: 29 Pages: 2259-2271
  • Peer Reviewed
• [Journal Article] Uterine cervical carcinoma : preoperative staging 3.0-T MR imaging-comparison with 1.5-T MR imaging (2009)
  • Author(s): Hori, M., Kim, T., Murakami, T., Imaoka, I., Onishi, H., Tomoda, K., Tsutsuui, T., Enomoto, T., Kimura, T., Nakamura, H.
  • Journal Title: Radiology Volume: 251 Pages: 96-104
  • Peer Reviewed
• [Journal Article] The activity of carboplatin and paclitaxel for recurrent cervical cancer after definitive radiotherapy (2009)
  • Author(s): Mabuchi, S., Morishige, K., Fujita, M., Tsutsui, T., Sakata, M., Enomoto, T., Kimura, T.
  • Journal Title: Gynecologic Oncology Volume: 113 Pages: 200-204
  • Peer Reviewed
• [Journal Article] Amniotic fluid 'sludge' detected in patients with subchorionic hematoma : a report of two cases (2009)
  • Author(s): Tskitishvili, E, Tomimatsu, T., Kanagawa, T., Sawada, Y., Kinugasa, Y., Mimura, K., Kimura, T.
  • Journal Title: Ultrasouond Obstet Gynecol Volume: 33 Pages: 484-486
  • Peer Reviewed
• [Journal Article] Peripheral quantitative computed tomography is useful to monitor response to alendronate therapy in postmenopausal women (2009)
  • Author(s): Sawada, K., Morishige, K., Nishio, Y., Hayakawa, J., Mabuchi, S., Iosbe, A., Ogata, S., Sakata, M., Ohmichi, M., Kimura, T.
  • Journal Title: J Bone Miner Metab Volume: 27 Pages: 175-181
  • NAID: 10025336716
  • Peer Reviewed
• [Journal Article] Cesarean scar pregnancies succseefully treated with methotrexate (2009)
  • Author(s): Muraji, M., Mabuchi, S., Hisamoto, K., Muranishi, M., Kanagawa, T., Nishio, Y., Kimura, T.
  • Journal Title: Acta Obstetricia et Gynecologica Scandinavica Volume: 88 Pages: 720-723
  • Peer Reviewed
• [Journal Article] Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy (2009)
  • Author(s): Ohno, S., Kyo, S., Myojo, S., Dohi, S., Ishizaki, J., Miyamoto, K-I., Morita, S., Sakamoto, J-I., Enomoto, T., Kimura, T., Oka, Y., Tsuboi, A., Sugiyama, H., Inoue, M.
  • Journal Title: Anticancer Research Volume: 29 Pages: 4779-4784
  • Peer Reviewed
• [Journal Article] A case of recurrent cesarean scar pregnancy (2009)
  • Author(s): Mabuchi, S., Kawase, C., Muraji, M., Kanagawa, T., Kimura, T.
  • Journal Title: Acta Obstetricia et Gynecologica Scandinavica Volume: 88 Pages: 1059-1060
  • Peer Reviewed
• [Journal Article] Metal transcription factor-1 is involved in hypoxia-dependent regulation of placenta growth factor in trophoblast-derived cells (2009)
  • Author(s): Nishimoto, F., Sakata, M., Minekawa, R., Okamoto, Y., Miyake, A., Isobe, A., Yamamoto, T., Takeda, T., Ishida, E., Sawada, K., Morishige, K-I., Kimura, T.
  • Journal Title: Endocrinology Volume: 150 Pages: 1801-1808
  • Peer Reviewed
• [Journal Article] Up-regulation of alpha5-integrin by E-cadherin loss in hypoxia and its key role in the migration of extravillous trophoblast cells during early implantation. (2009)
  • Author(s): Arimoto-Ishida, E., Sakata, M., Sawada, K., Nakayama, M., Nishimoto, F., Mabuchi, S., Takeda, T., Yamamoto, T., Isobe, A., Okamoto, Y., Lengyel, E., Suehara, N., Morishige, K., Kimura, T.
  • Journal Title: Endocrinology. Volume: 150 Pages: 4306-15
  • Peer Reviewed
• [Journal Article] Calcineurin/NFAT pathway : a novel regulator of parturition (2009)
  • Author(s): Tabata, C., Ogita, K., Sato, K., Nakamura, H., Negoro, H., Kumasawa, K., Temma-Asano, K., Tsutsui, T., Nishimori, K., Kimura, T.
  • Journal Title: American Journal of Reproductive Immunology Volume: 62 Pages: 44-50
  • Peer Reviewed
• [Journal Article] MR Imaging of endometrial carcinoma for preoperative staging at 3.0 T : comparison with imaging at 1.5 T (2009)
  • Author(s): Hori, M., Kim, T., Murakami, T., Imaoka, I., Onishi, H., Nakamoto, A., Nakaya, Y., Tomoda, K., Tsutsui, T., Enomoto, T., Kimura, T., Nakamura, H.
  • Journal Title: Journal of Magnetic Resonance Imaging Volume: 30 Pages: 621-630
  • Peer Reviewed
• [Journal Article] mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. (2009)
  • Author(s): Mabuchi, S., Kawase, C., Altomare, DA., Morishige, K., Sawada, K., Hayashi, M., Tsujimoto, M., Yamoto, M., Klein-Szanto, AJ., Schilder, RJ., Ohmichi, M., Testa, JR., Kimura, T.
  • Journal Title: Clin Cancer Res. Volume: 15 Pages: 5404-13
  • Peer Reviewed
• [Journal Article] Postoperative concurrent nedaplatin-based chemoradiotherapy imprves survival in early-stage cervical cancer patients with adverse risk factors. (2009)
  • Author(s): Mabuchi, S., Morishige, K., Isohashi, F., Yoshioka, Y., Takeda, T., Yamamoto, T., Yoshino, K., Enomoto, T., Inoue, T., Kimura, T.
  • Journal Title: Gynecologic Oncology Volume: 115 Pages: 482-487
  • Peer Reviewed
• [Journal Article] Postpartum outcome of cervical intraepithelial neoplasia in pregnant women determined determined b route of delivery (2009)
  • Author(s): Ueda, Y., Enomoto, T., Miyatake, T., Yoshino, K., Fujita, M., Miyake, T., Fujiwara, K., Muraji, M., Kanagawa, T., Kimura, T.
  • Journal Title: Reproductive Science Volume: 16 Pages: 1034-1039
  • Peer Reviewed
• [Journal Article] Fasudil inhibits lysophosphatidic acid-induced invasiveness of human ovarian cancer cells. (2009)
  • Author(s): Ogata, S., Morishige, K., Sawada, K., Hashimoto, K., Mabuchi, S., Kawase, C., Ooyagi, C., Sakata, M., Kimura, T.
  • Journal Title: Int J Gynecol Cancer. Volume: 19 Pages: 1473-1480
  • Peer Reviewed
• [Journal Article] 妊娠子宮局所におけるマクロファージの役割 (2009)
  • Author(s): 中村仁美、香山晋輔、谷口武、荻田和秀、熊澤恵一、張慶、筒井建紀、古山将康、杉野法広、田村博史、金田安史、木村正
  • Journal Title: 生殖内分泌学会雑誌 Volume: 14巻 Pages: 35-40
  • Peer Reviewed
• [Journal Article] Central aortic blood pressure and Augmentation index during normal pregnancy
  • Author(s): Fujime, M., Tomimatsu, T., Okaue, Y., Koyama, S., Kanagawa, T., Taniguchi, T., Kimura, T
  • Journal Title: Hypertens Res. Volume: (in press)
  • NAID: 10030956198
  • Peer Reviewed
• [Journal Article] Estimation of mouse fetal weight by ultrasonography : application from clinic to laboratory
  • Author(s): Nguyen TM, Nakamura, H., Wakabayashi, A., Kanagawa, T., Koyama, S., Tsutsui, T., Hamasaki, T., Kimura, T
  • Journal Title: Laboratory Animals Volume: (in press)
  • Peer Reviewed
• [Journal Article] Partial gastrectomy using natural orifice translumenal endoscopic surgery (NOTES) for gastric submucosal tumors : early experience in humans
  • Author(s): Nakajima, K., Nishida, T., Takahashi, T., Souma, Y., Hara, J., Yamada, T., Yoshio, T., Tsutsui, T., Yokoi, T., Mori, M., Doki, Y
  • Journal Title: Surg Endosc Volume: (In press)
  • Peer Reviewed
• [Journal Article] The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse : a pilot study.
  • Author(s): Tskitishvili E, Nakamura H, Kinugasa-Taniguchi Y, Kanagawa T, Shimoya K, Tomimatsu T, Kimura T.
  • Journal Title: Am J Obstet Gynecol Volume: (In press)
  • Peer Reviewed
• [Presentation] Effects of dexamethasone given to immature rats on behavior after growth (2012)
  • Author(s): Hosono, T., Nitta, C., Iseki, T., Yamamoto, M., Igi, C
  • Organizer: 第89回日本生理学会大会
  • Place of Presentation: 松本市
  • Year and Date: 2012-03-31
• [Presentation] 不育症に対する抗血小板療法・抗凝固療法に関するアンケート調査の解析 (2011)
  • Author(s): 正木秀武、筒井建紀、中村仁美、香山晋輔、田畑知沙、熊澤恵一、後安聡子、藤森由香、木村正
  • Organizer: 第56回日本生殖医学会学術講演会・総会
  • Place of Presentation: 横浜市
  • Year and Date: 2011-12-08
• [Presentation] 不育症治療としての抗血小板療法・抗凝固療法に関するアンケート調査 (2011)
  • Author(s): 筒井建紀、正木秀武、香山晋輔、田畑知沙、熊澤恵一、中村仁美、木村正
  • Organizer: 第26回日本生殖免疫学会総会・学術集会
  • Place of Presentation: 名古屋市
  • Year and Date: 2011-12-02
• [Presentation] 中隔子宮に対する子宮鏡下中隔切除術 (2011)
  • Author(s): 筒井建紀、木村正
  • Organizer: 第34回日本産婦人科手術学会
  • Place of Presentation: 福岡市
  • Year and Date: 2011-11-27
• [Presentation] Effects of administration of dexamethasone to immature rats assessed behaviorally during and after growth (2011)
  • Author(s): Hosono, T., Iseki, T., Yamamoto, M., Igi, C., Minato, K
  • Organizer: Neuroscience 2011 Walter E
  • Place of Presentation: Washington Convention Center, Washington, USA
  • Year and Date: 2011-11-16
• [Presentation] Effects of administration of dexamethasone to immature rats assessed behaviorally during and after growth (2011)
  • Author(s): Hosono, I, Iseki, T, Yamamoto, M., Igi, C, Minato, K.
  • Organizer: Neuroscience 2011
  • Place of Presentation: Walter E.Washington Convention Center, Washington, USA
  • Year and Date: 2011-11-16
• [Presentation] Development of a new drug delivery systrem for uterus usingbionanocapsule(BNC) (2011)
  • Author(s): Nakamura, H., Koyama, S., Tabata, C., Thang, N., Takiuchi, T., Masaki, H., Tsutsui, T., Kimura, T
  • Organizer: 第63回日本産科婦人科学会・学術講演会
  • Place of Presentation: 大阪市
  • Year and Date: 2011-08-29
• [Presentation] Development of a new drug delivery systrem for uterus usingbionanoca psule(BNC) (2011)
  • Author(s): Nakamura, H., Koyama, S., Tabata, C, Thang, N., Takiuchi, T., Masaki, H., Tsutsui, T., Kimura, T.
  • Organizer: 第63回日本産科婦人科学会・学術講演会
  • Place of Presentation: 大阪市
  • Year and Date: 2011-08-29
• [Presentation] 早期子宮体癌に対する腹腔鏡下手術の検討 (2011)
  • Author(s): 横井猛、小林栄仁、筒井建紀、木村正
  • Organizer: 第51回日本産婦人科内視鏡学会学術講演会
  • Place of Presentation: 大阪市
  • Year and Date: 2011-08-04
• [Presentation] 腹腔鏡下手術を施行した非交通性副角を伴う単角子宮の5症例 (2011)
  • Author(s): 筒井建紀、横井猛、瀧内剛、金山智子、小林栄仁、木村正
  • Organizer: 第51回日本産科婦人科内視鏡学会学術講演会
  • Place of Presentation: 大阪市
  • Year and Date: 2011-08-04
• [Presentation] 不育症に対する抗血小板療法/抗凝固療法に関するアンケート調査 (2011)
  • Author(s): 田畑知沙、筒井建紀、林正美、中村仁美、大八木知史、若林敦子、瀧内剛、正木秀武、筒井建紀、香山晋輔、木村正
  • Organizer: 第136回日本生殖医学会関西支部集団会第42回関西アンドロロジーカンファレンス
  • Place of Presentation: ハービスPLAZA(大阪市)
  • Year and Date: 2011-03-05
• [Presentation] Prediction of prognoses of fetuses with congenital heart diseases using fetal magnetocardiogram (2010)
  • Author(s): Akeno H, Hosono T
  • Organizer: The 3rd Asian Symposium on Magnetocardiographyn
  • Place of Presentation: 筑波市
  • Year and Date: 2010-12-09
• [Presentation] Prediction of prognoses of fetuses with congenital heart diseases using fetal magnetocar diogram (2010)
  • Author(s): Akeno H, Hosono T
  • Organizer: The 3rd Asian Symposium on Magnetocardiographyn
  • Place of Presentation: Tsukuba, Japan
  • Year and Date: 2010-12-09
• [Presentation] Significance of feto-maternal interface : from implantation failure to preeclampsia in model mice (2010)
  • Author(s): Kimura, T., Zhang Q, Nakamura, H., Kumasawa K, Koyama, S., Tabata C, Tsutsui, T
  • Organizer: 2nd International Conference on Reproductive Immunology
  • Place of Presentation: Shanghai, China
  • Year and Date: 2010-10-02
• [Presentation] Significance of feto-maternal interface : from implantation failure to preeclampsia in model mice. (2010)
  • Author(s): Kimura T, Zhang Q, Nakamura H, Kumasawa K, Koyama S, Tabata C, Tsutsui T
  • Organizer: 2nd International Conference on Reproductive Immunology
  • Place of Presentation: Shanghai, China(招待講演)
  • Year and Date: 2010-10-02
• [Presentation] Prediction of fetal prognosis using indexes in time and amplitude domains of fetal magnetocardiogram (2010)
  • Author(s): Hosono, T
  • Organizer: Global Congress of Maternal and Infant Health
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2010-09-25
• [Presentation] Bizarre expression of tissue inhibitor of metalloproteinase-3 in feto-maternal interface caused gestational hypertension in mice model (2010)
  • Author(s): Kimura, T., Zhang Q, Nakamura, H., Kumasawa K, Koyama, S., Tabata C, Tsutsui, T
  • Organizer: XI International Congress of Reproductive Immunology Cairns
  • Place of Presentation: AUSTRALIA
• [Presentation] Modelling uterine macrophage-epithelial cell communication in vitro using peripheral blood monocytes (2010)
  • Author(s): Nakamura, H., Jasper M, Robertson S, Kimura, T
  • Organizer: XI International Congress of Reproductive Immunology Cairns
  • Place of Presentation: AUSTRALIA
• [Presentation] 子宮の着床能を評価するための生理的パラメーターの検索 (2010)
  • Author(s): 中村仁美、細野剛良、木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都
• [Presentation] 子宮の着床能を評価するための生理的パラメーターの検索 (2010)
  • Author(s): 中村仁美、細野剛良、木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 末梢血単球細胞を用いた着床子宮局所におけるマクロファージの体外での再構築 (2010)
  • Author(s): 田畑知沙, 中村仁美, 香山晋輔, 筒井建紀, 木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 中隔子宮患者には、排卵障害が多いか? (2010)
  • Author(s): 筒井建紀, 香山晋輔, 田畑知沙, 朝野久美子, 中村仁美, 熊澤恵一, 前田真紀子, 根來英典, 木村正, 松下克子, 朝倉寛之
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 胎児頭蓋内出血を来たした特発性血小板減少性紫斑病(Idiopathic Thrombocytopenic Purpura : ITP)合併妊娠の一症例 (2010)
  • Author(s): 香山晋輔、和田朋、谷口友基子、磯部晶、金川武司、澤田健二朗、冨松拓治、木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 動脈スティフネスの非侵襲的測定による高血圧症候群の早期診断の可能性 (2010)
  • Author(s): 藤目美佳、富松拓治、和田朋、谷口友基子、香山晋輔、磯部晶、金川武司、澤田健二郎、木村正、谷口武
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 妊娠中に発見された横行結腸癌由来の腹膜偽粘液腫の一症例 (2010)
  • Author(s): 佐々本尚子、香山晋輔、谷口友基子、磯部晶、金川武司、澤田健二郎、冨松拓治、瀧内剛、宮武崇、木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 母体心停止後の胎児評価について～縊頸にて最低20分の母体心停止があった後に搬送・分娩となった1症例～ (2010)
  • Author(s): 和田朋、冨松拓治、谷口友礎子、香山晋輔、磯部晶、金川武司、澤田健二郎、木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 当施設でのもやもや病合併妊娠の予後に関する-妊娠中に出血症状により初めて診断されたもやもや合併症妊娠の1例を通じて- (2010)
  • Author(s): 三宅達也、冨松拓治、谷口友基子、香山晋輔、磯部晶、金川武司、澤田健二郎、木村正、荻田和秀
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] 片側卵巣摘出により排卵が回復した妊娠に至ったMcCune-Albright syndrome1の1例 (2010)
  • Author(s): 横井猛, 足立和繁, 筒井建紀, 森重健一郎, 木村正
  • Organizer: 第62回日本産婦人科学会学術講演会
  • Place of Presentation: 東京都(東京国際フォーラム)
• [Presentation] Mayer-Rokitansky-Kuster-Hauser syndromeに対して施行した腹腔鏡補助下造膣術(Davydov変法)の検討 (2010)
  • Author(s): 瀧内剛, 香山晋輔, 横井猛, 金山智子, 筒井建紀, 木村正
  • Organizer: 第50回日本産婦人科内視鏡学会学術講演会
  • Place of Presentation: 東京都(京王プラザホテル)
• [Presentation] 中隔子宮を有する挙児希望患者に対する子宮鏡下中隔子宮切除述後の妊娠予後 (2010)
  • Author(s): 筒井建紀, 香山晋輔, 田畑知沙, 横井猛, 木村正, 朝倉寛之
  • Organizer: 第50回日本産婦人科内視鏡学会学術講演会
  • Place of Presentation: 東京都(京王プラザホテル)
• [Presentation] Bizarre expression of tissue inhibitor of metalloproteinase-3 in feto-maternal interface caused gestational hypertension in mice model (2010)
  • Author(s): Kimura T, Zhang Q, Nakamura H, Kumasawa K, Koyama S, Tabata C, Tsutsui T
  • Organizer: XI International Congress of Reproductive Immunology
  • Place of Presentation: Cairns, AUSTRALIA
• [Presentation] Modelling uterine macrophage-epithelial cell communication in vitro using peripheral blood monocytes. (2010)
  • Author(s): Nakamura H, Jasper M, Robertson S, Kimura T
  • Organizer: XI International Congress of Reproductive Immunology
  • Place of Presentation: Cairns, AUSTRALIA
• [Presentation] Endometrial Stat3 activation and implantation failure (2009)
  • Author(s): Kimura, T
  • Organizer: IUPS Satellite Symposium on Endometrial Receptivity and Blastocyst Implantation
  • Place of Presentation: Inamori Hall, Kyoto University
  • Year and Date: 2009-07-25
• [Presentation] Investigation of uterine parameters to evaluate uterine receptivity (2009)
  • Author(s): Nakamura H., Hosono T., Kimura T
  • Organizer: IUPS Satellite Symposium on Endometrial Receptivity and Blastocyst Implantation
  • Place of Presentation: Inamori Hall, Kyoto University
  • Year and Date: 2009-07-25
• [Presentation] Mouse model of human infertility : transient and local inhibition of endometrial STAT-3 activation results in implantation failure (2009)
  • Author(s): Kimura, T
  • Organizer: 5^<th> International Conference on the Female Reproductive Tact Frauenchiemsee
  • Place of Presentation: Germany
  • Year and Date: 2009-05-17
• [Presentation] Macrophage regulation of embryo adhesion molecule in human endometrial epithelial cells (2009)
  • Author(s): Nakamura H, Jasper MJ, Aplin JD, Kimura T, Robertson SA
  • Organizer: 5^<th> International Conference on the Female Reproductive Tact Frauenchiemsee
  • Place of Presentation: Germany
  • Year and Date: 2009-05-17
• [Presentation] Mouse model of human infertility : transient and local inhibition of endo metrial STAT-3 activation results in implantation failure (2009)
  • Author(s): Kimura, T.
  • Organizer: 5^<th> International Conference on the Female Reproductive Tact
  • Place of Presentation: Frauenchiemsee, Germany
  • Year and Date: 2009-05-17
• [Book] 第24章生殖補助医療 (2011)
  • Author(s): 香山晋輔、木村正
  • Publisher: メディカ出版
• [Book] 子宮筋腫・子宮腺筋症と生殖 (2011)
  • Author(s): 筒井建紀
  • Publisher: 産婦人科学レビュー
• [Book] 副角子宮・片側形成不全 (2011)
  • Author(s): 筒井建紀
  • Publisher: メディカルビュー社
• [Patent(Industrial Property Rights)] 子宮着床能の測定方法、測定装置及び測定装置の作動方法 (2011)
  • Inventor(s): Hitomi Nakamura, Tadashi Kimura, Takayoshi Hosono
  • Industrial Property Rights Holder: Osaka University
  • Acquisition Date: 2011-11-20
  • Overseas
• [Patent(Industrial Property Rights)] 子宮着床能の測定方法及び測定装置 (2010)
  • Inventor(s): 中村仁美、木村正、細野剛良
  • Industrial Property Rights Holder: 大阪大学
  • Industrial Property Number: 2010-260006
  • Filing Date: 2010-11-22
• [Patent(Industrial Property Rights)] 子宮着床能判定機器 (2010)
  • Inventor(s): 中村仁美, 木村正, 細野剛良
  • Industrial Property Rights Holder: 大阪大学
  • Industrial Property Number: 2010-260006
  • Filing Date: 2010-11-22