Basic Research on the Inner Ear Protection During Partial Destruction of the Inner Ear
| Project/Area Number |
21390457
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAWASE Tetsuaki 東北大学, 大学院・医工学研究科, 教授 (50169728)
OSHIMA Takeshi 東北大学, 大学院・医学系研究科, 准教授 (40241608)
KAMAKURA Shinji 東北大学, 大学院・医工学研究科, 教授 (80224640)
NAKAYA Kazuhiro 東北大学, 病院, 助教 (60466563)
HIDAKA Hiroshi 東北大学, 病院, 講師 (40302103)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
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| Keywords | 内耳切断 / 内耳保護 / 内耳電位 / イオン / モルモット / 耳毒性 / ダプトマシシン / ABR / 内リンパ電位 / イオン濃度 / 半規管瘻孔 / 半規管 / 半規管膨大部 / 前庭 / 内耳電 |
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| Research Abstract |
1)Disturbance of the mechanism of cochlear function caused by vestibular labyrinth destruction may involve reduction in the [K(+)] concentration in the endolymph.
2) Stopping endolymphatic leakage may be the most important factor to prevent acute phasehearing impairment.
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Report
(5 results)
Research Products
(23 results)
