| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2009: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
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| Research Abstract |
Several studies suggested neural stem cells in the hippocampal dentate gyrus are affected by the external circumstances. First, we suggested the reduced mastication influenced the survival of the neural stem cells in the dentate gyrus through the nitric oxide production system. Second, mice were fed hard diet or given blocks of tree for biting for 8 weeks. The survivals of neural stem cells in both of the mastication groups were significantly in creased. In conclusion, these data showed possibilities that the mastication affect the neural plasticity in the central nervous system.
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