Budget Amount *help |
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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Research Abstract |
Periodontal disease is not merely a local infectious disease, but also a low-grade inflammatory disease for the host which may greatly influences glucose tolerance as well as cardiovascular risk. Therefore, our understanding the mechanisms behind this phenomenon at molecular basis is important to establish healthy longevity. Here, we found activated immune cells by periodontal infection migrated into adipose tissues, interacted with adipocytes, thereby enhancing immune responses as well as influencing lipid and glucose metabolism. It is strongly indicataed that the purpose of periodontal treatment is not only to avoid tooth extraction, but also to achieve healthy longevity.
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