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10-year mortality following cohort study in an 80-year-old community dwelling population

Research Project

Project/Area Number 21390560
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionKyushu Dental College

Principal Investigator

TAKATA Yutaka  九州歯科大学, 歯学部, 教授 (40163208)

Co-Investigator(Kenkyū-buntansha) ANSAI Toshihiro  九州歯科大学, 歯学部, 教授 (80244789)
SOH Inho  九州歯科大学, 歯学部, 助教 (10285463)
AWANO Shuji  九州歯科大学, 歯学部, 講師 (20301442)
SONOKI Kazuo  九州歯科大学, 歯学部, 准教授 (50316155)
HAMASAKI Tomoko  九州歯科大学, 歯学部, 助教 (60316156)
TORISU Takehiro  九州歯科大学, 歯学部, 助教 (30453228)
YOSHIDA Akihiro  九州歯科大学, 歯学部, 助教 (20364151)
NAKAMICHI Ikuo  九州歯科大学, 歯学部, 助教 (60419570)
KAGIYAMA Shuntarou  九州歯科大学, 歯学部, 助教 (50433404)
TAKEHARA Tadamichi  九州歯科大学, 歯学部, 教授 (00038879)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords予防歯科学 / 高齢者 / 死亡率 / 口腔 / 歯 / 追跡調査 / 死因 / 地域住民 / 疫学
Research Abstract

During follow-up period of 12 years, 506 died(total mortality, 64.7%), 276 were alive, and 42 were lost(follow-up rate, 94.9%) out of 824 subjects who participated in the present study in 1998.Out of the 506 who died, 128 died due to cardiovascular disease(25.3%), 96 to respiratory tract disease(19.0%), 87 to cancer(17.2%), and 51 to senility(10.1%). Number of teeth at the start of the study of 80-year-old individuals was 6.8 for those who died, and 8.3 for those who remained alive(P=0.026). Association in 12-mortality with chewing ability or teeth number at age of 80 year was assessed using Kaplan-Meier methods. All subjects were classified according to the number of foods to chew(poor chewing, 0-4 ; slightly poor, 5-9 ; slightly good, 10-14 ; good chewing, 15), or number of teeth(0 ; 1-9 ; 10-19 ;≧20). There was a significant difference among groups for chewing ability, while no difference was found among groups for number of teeth. Total mortality using Cox proportional hazards regression model, which were adjusted for gender, was 2.1 times more prevalent in subjects with poor chewing, 1.4 times more prevalent in those with slightly poor chewing, and 1.3 times more prevalent in those with slightly good chewing as compared to those with good chewing. The risk for total mortality associated with increase in 1 chewable food decreased 4.5% after adjustment for gender difference. Similarly, risk of all-cause mortality adjusted for gender difference was decreased 1.5% with an increase in 1 tooth. These findings suggest that preserving chewing ability or remaining teeth at the age of 80 may be associated with longenity.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (48 results)

All 2012 2011 2010 2009 Other

All Journal Article (25 results) (of which Peer Reviewed: 8 results) Presentation (16 results) Book (6 results) Remarks (1 results)

  • [Journal Article] Serum albumin(SA) levels and 10-year mortality in a community-dwelling 70-year-old population2012

    • Author(s)
      Y Takata, T Ansai, A Yoshihara, H Miyazaki
    • Journal Title

      Archives Gerontology Geriatric

      Volume: 54 Pages: 39-43

    • URL

      http://dx.doi.org/10.1016/j.archger.2011.02.018

    • Related Report
      2011 Final Research Report
  • [Journal Article] Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population2012

    • Author(s)
      Y Takata, T Ansai, I Soh, S Awano, Y Yoshitake, Y Kimura, I Nakamichi, K Goto, R Fujisawa, K Sonoki, A Yoshida, K Toyoshima, T Nishihara
    • Journal Title

      Archives Gerontology Geriatric

      Volume: 54 Pages: 28-33

    • URL

      http://dx.doi.org/10.1016/j.archger.2011.04.014

    • Related Report
      2011 Final Research Report
  • [Journal Article] Serum albumin (SA) levels and 10-year mortality in a community-dwelling 70-year-old population2012

    • Author(s)
      Takata Y, Ansai T, Yoshihara A, Miyazaki H
    • Journal Title

      Archives of Gerontology and Geriatrics

      Volume: 54(1) Issue: 1 Pages: 39-43

    • DOI

      10.1016/j.archger.2011.02.018

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population2012

    • Author(s)
      Takata Y, TAnsai T, Soh I, Awano S, Yoshitake Y, et al
    • Journal Title

      Archives of Gerontology and Geriatrics

      Volume: 54(1) Issue: 1 Pages: 28-33

    • DOI

      10.1016/j.archger.2011.04.014

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlations between health status and oral chromaTM-determined volatile sulfide levels in mouth air of the elderly2011

    • Author(s)
      Awano S, Takata Y, Soh I, Yoshida A, Hamasaki T, Sonoki K, Ohsumi T, Nishihara T, Ansai T
    • Journal Title

      J Breath Res

      Volume: 5(4) Pages: 46007-46007

    • URL

      http://dx.doi.org/10.1088/1752-7155/5/4/046007

    • Related Report
      2011 Final Research Report
  • [Journal Article] Glomerular filtration rate and 10-year mortality in a 70-year-old community-dwelling Japanese population2011

    • Author(s)
      Y Takata, T Ansai, A Yoshihara, H Miyazaki
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: 23(3) Pages: 223-230

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 健康増進に向けた咀嚼の位置づけとは2011

    • Author(s)
      安細敏弘、高田豊
    • Journal Title

      九州歯会誌

      Volume: 65(3) Pages: 53-59

    • NAID

      10029478672

    • URL

      http://www.kyu-dent.ac.jp

    • Related Report
      2011 Final Research Report
  • [Journal Article] Association between impaired dental status and cardiovascular mortality in elderly subjects2011

    • Author(s)
      Ansai T, Takata Y
    • Journal Title

      Journal of Dental Health

      Volume: 61 Pages: 153-158

    • NAID

      40018835977

    • URL

      http://www.kokuhoken.or.jp

    • Related Report
      2011 Final Research Report
  • [Journal Article] Quality of life and physical fitness in an 85-year-old population2010

    • Author(s)
      Y Takata, T Ansai, I Soh, S Awano, Y Yoshitake, Y Kimura, K Sonoki, S Kagiyama, A Yoshida, I Nakamichi, T Hamasaki, T Torisu, K Toyoshima, T Takehara
    • Journal Title

      Archives Gerontology Geriatrics

      Volume: 50 Pages: 272-276

    • URL

      http://dx.doi.org/10.1016/j.archger.2009.04.005

    • Related Report
      2011 Final Research Report
  • [Journal Article] Serum albumin levels as an independent predictor of 4-year mortality in a community-dwelling 80-year-old population2010

    • Author(s)
      Y Takata, T Ansai, I Soh, S Awano, K Sonoki, S Akifusa, S Kagiyama, T Hamasaki, T Torisu, A Yoshida, I Nakamichi and T Takchara
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: 22(1) Pages: 31-35

    • URL

      http://www.kurtis.it/aging/it/

    • Related Report
      2011 Final Research Report
  • [Journal Article] Relationship between tooth loss and mortality in 80-year-old Japanese community-dwelling subjects2010

    • Author(s)
      T Ansai, Y Takata, I Soh, S Awano, A Yoshida, K Sonoki, T Hamasaki, T Torisu, A Sogame, N Shimada and T Takehara
    • Journal Title

      BMC Public Health

      Volume: 10 Issue: 1 Pages: 386-386

    • DOI

      10.1186/1471-2458-10-386

    • Related Report
      2011 Final Research Report
  • [Journal Article] Serum albumin levels as an independent predictor of 4-year mortality in a community-dwelling 80-year-old population.2010

    • Author(s)
      Takata Y, Ansai T, et al.
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: 22(1) Pages: 31-35

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quality of life and physical fitness in an 85-year-old population.2010

    • Author(s)
      Takata Y, Ansai T, et al.
    • Journal Title

      Archives Gerontology Geriatrics

      Volume: 50 Pages: 272-276

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between tooth loss and mortality in 80-year-old Japanese community-dwelling subjects.2010

    • Author(s)
      Ansai T, Takata Y, et al.
    • Journal Title

      BMC Public Health

      Volume: 10

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cognitive function and number of teeth in a community-dwelling elderly population without dementia2009

    • Author(s)
      Y Takata, T Ansai, I Soh, K Sonoki, S Awano, Nakamichi I, T Hamasaki, S Kagiyama, A Yoshida, T Torisu, T Ohsumi, K Toyoshima, T Nishihara, and T Takehara
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 36 Issue: 11 Pages: 808-813

    • DOI

      10.1111/j.1365-2842.2009.01998.x

    • Related Report
      2011 Final Research Report
  • [Journal Article] IgA level is associated with risk for mortality in 80-year old population2009

    • Author(s)
      Torisu T, Takata Y, Ansai T, Soh I, Awano S, Sonoki K, Kagiyama S, Nakamichi I, Yoshida A, Hamasaki T, Matsumoto T, Iida M, Takehara T
    • Journal Title

      Gerontology

      Volume: 55(2) Issue: 2 Pages: 179-185

    • DOI

      10.1159/000162260

    • Related Report
      2011 Final Research Report
  • [Journal Article] Associations among hair loss, oral sulfur-containing gases, and gastrointestinal and metabolic linked diseases in Japanese elderly men : pilot study2009

    • Author(s)
      T Ansai, S Awano, I Soh, Y Takata, A Yoshida, T Hamasak, T Takehara
    • Journal Title

      BMC Public Health

      Volume: 9(82) Issue: 1 Pages: 1-6

    • DOI

      10.1186/1471-2458-9-82

    • Related Report
      2011 Final Research Report
  • [Journal Article] Possible Association of Atrophic Gastritis and Arterial Stiffness in Healthy Middle-Aged Japanese2009

    • Author(s)
      Torisu T, Takata Y, Ansai T, Matsumoto T, Sonoki K, Soh I, Awano S, Yoshida A, Hamasaki T, Kagiyama S, Nakamichi I, Ohsumi T, Toyoshima K, Nishihara T, Iida M, Takehara T.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 16 Issue: 5 Pages: 691-697

    • DOI

      10.5551/jat.943

    • NAID

      130004444334

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2011 Final Research Report
  • [Journal Article] Correlation Between Increased Urinary Sodium Excretion and Decreased Left Ventricular Diastolic Function in Patients with type 2 Diabetes Mellitus2009

    • Author(s)
      Kagiyama S, Koga T, Kaseda S, Ishihara S, Kawazoe N, Sadoshima S, Matsumura K, Takata Y, Tsuchihashi T, Iida M
    • Journal Title

      Clinical Cardiology

      Volume: 32 Issue: 10 Pages: 569-574

    • DOI

      10.1002/clc.20664

    • Related Report
      2011 Final Research Report
  • [Journal Article] Does decreased diastolic blood pressure associate with increased mortality in 80-year-old Japanese?2009

    • Author(s)
      Kagiyama S, Takata Y, Ansai T, Matsumura K, Soh I, Awano S, Sonoki K, Yoshida A, Torisu T, Hamasaki T, Nakamichi I, Takehara T, Iida M
    • Journal Title

      Clinical and Experimental Hypertension

      Volume: 31(8) Issue: 8 Pages: 639-647

    • DOI

      10.3109/10641960903407009

    • Related Report
      2011 Final Research Report
  • [Journal Article] Determination of cortisol and dehydroepiandrosterone levels in saliva for screening of periodontitis in older Japanese adults2009

    • Author(s)
      T Ansai, I Soh, A Ishisaka, A Yoshida, S Awano, T Hamasaki, K Sonoki, Y Takata, T Takehara
    • Journal Title

      International Journal of Dentistry

      Volume: 280737 Pages: 8-8

    • DOI

      10.1155/2009/280737

    • Related Report
      2011 Final Research Report
  • [Journal Article] Cognitive function and number of teeth in a community-dwelling elderly population without dementia.2009

    • Author(s)
      Y Takata, T Ansai, I Soh, K Sonoki, S Awano, Nakamichi I, T Hamasaki, その他
    • Journal Title

      Journal of Oral Rehabilitation 36

      Pages: 808-813

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible association of atrophic gastritis and arterial stiffness in healthy middle-aged Japanese.2009

    • Author(s)
      Torisu T, Takata Y, Ansai T, Matsumoto T, Sonoki K, Soh I, Awano S, その他
    • Journal Title

      Journal of Atherosclerosis and Thrombosis 16

      Pages: 691-697

    • NAID

      10026143884

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Does decreased diastolic blood pressure associate with increased mortality in 80-year-old Japanese?2009

    • Author(s)
      Kagiyama S, Takata Y, Ansai T, Matsumura K, Soh I, Awano S, Sonoki K, その他
    • Journal Title

      Clinical and Experimental Hypertension 31

      Pages: 639-647

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical performance and 10-year mortality in a 70-year-old community-dwelling population

    • Author(s)
      Y Takata, M Shimada, T Ansai, Y Yoshitake, M Nishimuta, N Nakagawa, M Ohashi, A Yoshihara, H Miyazaki
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: (in press)

    • URL

      http://www.kurtis.it/aging/it/

    • Related Report
      2011 Final Research Report
  • [Presentation] 福岡県在住80歳高齢者を対象にした追跡コホート研究2012

    • Author(s)
      安細敏弘、高田豊、邵仁浩、粟野秀慈、吉田明弘、園木一男、中道郁夫、後藤健一
    • Organizer
      第72回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report
  • [Presentation] 80歳高齢者住民の12年間追跡による生命予後と咀嚼機能・現在歯数との関連性(シンポジウム2 ;咬合咀嚼は健康長寿にどのように貢献しているのか)2012

    • Author(s)
      高田豊、安細敏弘
    • Organizer
      日本補綴歯科学会
    • Place of Presentation
      神奈川県民ホール
    • Related Report
      2011 Final Research Report
  • [Presentation] 80歳高齢住民の12年間追跡による生命予後と喪失歯数との関連(シンポジウム:口は禍のもとー口腔から考える全身医療)2012

    • Author(s)
      安細敏弘・高田豊
    • Organizer
      第12回日本抗加齢医学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯周病治療の動脈硬化への影響-脈波伝導速度での検討-2011

    • Author(s)
      後藤健一、園木一男、中道郁夫、鳥巣剛弘、高田豊、横田誠
    • Organizer
      第71回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report
  • [Presentation] 福岡県在住80歳高齢者を対象にした追跡コホート研究2011

    • Author(s)
      安細敏弘、高田豊、邵仁浩、粟野秀慈、吉田明弘、峰岡哲郎、園木一男、中道郁夫、後藤健一、藤澤律子
    • Organizer
      第71回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 80歳の残歯数は5年間の体重変化と相関する2010

    • Author(s)
      鍵山俊太郎、高田豊、安細敏弘、園木一男、粟野秀慈、鳥巣剛弘、中道郁夫、竹原直道
    • Organizer
      第107回日本内科学会総会
    • Place of Presentation
      東京国際フォーラム、東京
    • Related Report
      2011 Final Research Report
  • [Presentation] 福岡県在住80歳高齢者を対象にした追跡コホート研究2010

    • Author(s)
      安細敏弘・高田豊・邵仁浩・粟野秀慈・吉田明弘・園木一男・竹原直道
    • Organizer
      第70回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 血液透析患者の口腔と全身健康に関する研究-糖尿病性腎症患者の口腔健康について-2009

    • Author(s)
      粟野秀慈、寺谷豪、木下直昌、安細敏弘、邵仁浩、吉田明弘、濱崎朋子、高田豊、竹原直道
    • Organizer
      第58回日本口腔衛生学会総会
    • Place of Presentation
      長良川国際会議場、岐阜
    • Year and Date
      2009-10-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔から全身の健康を科学する2009

    • Author(s)
      高田豊
    • Organizer
      第31回日本口腔衛生学会九州地方会総会・特別講演
    • Place of Presentation
      北九州市
    • Year and Date
      2009-07-05
    • Related Report
      2011 Final Research Report
  • [Presentation] 口腔から全身の健康を科学する2009

    • Author(s)
      高田豊
    • Organizer
      第31回日本口腔衛生学会九州地方会総会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-07-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Decreased diastolic blood pressure associated increased mortality in 80-year-old Japanese2009

    • Author(s)
      鍵山俊太郎、高田豊、松村潔、飯田三雄
    • Organizer
      第73回日本循環器学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2011 Final Research Report
  • [Presentation] Diastolic blood pressure is associated with hydrogen sulphide level in mouth air2009

    • Author(s)
      S. Awano, T. Ansai, Y. Takata, I. Soh, A. Yoshida, T. Hamasaki, K. Sonoki, T. Takehara
    • Organizer
      8th International Conference of the International Society for Breath Odor Research
    • Place of Presentation
      Dortmund, Germany
    • Related Report
      2011 Final Research Report
  • [Presentation] 福岡県在住80歳高齢者を対象にしたコホート研究における歯の喪失と長寿の関連2009

    • Author(s)
      安細敏弘・邵仁浩・高田豊・粟野秀慈・吉田明弘・濱崎朋子・園木一男・竹原直道
    • Organizer
      第69回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report
  • [Presentation] 地域住民を対象とした口腔と全身健康に関する疫学研究-血液透析患者の口腔と全身健康についての報告-2009

    • Author(s)
      粟野秀慈, 安細敏弘, 高田豊, 邵仁浩, 吉田明弘, 濱崎朋子, 園木一男, 竹原直道
    • Organizer
      第69回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Related Report
      2011 Final Research Report
  • [Presentation] 80歳高齢者を対象にしたコホート研究における歯の喪失と寿命の関連-喫煙習慣による層別分析からの考察2009

    • Author(s)
      安細敏弘、邵仁浩、粟野秀慈、吉田明弘、濱嵜朋子、高田豊、竹原直道
    • Organizer
      第58回日本口腔衛生学会総会
    • Place of Presentation
      長良川国際会議場、岐阜
    • Related Report
      2011 Final Research Report
  • [Presentation] 血液透析患者の口腔と全身健康に関する研究2-血液透析患者のQOLに影響を与える口腔関連リスク因子について2009

    • Author(s)
      寺谷豪、粟野秀慈、木下直昌、濱嵜朋子、邵仁浩、吉田明弘、安細敏弘、高田豊、竹原直道
    • Organizer
      第58回日本口腔衛生学会総会
    • Place of Presentation
      長良川国際会議場、岐阜
    • Related Report
      2011 Final Research Report
  • [Book] Association of Disease-Specific Mortality with Physical Fitness Measurements and Nonparticipation in an 80-Year-Old Population2012

    • Author(s)
      Y Takata, T Ansai, I Soh, S Awano, Y Yoshitake, Y Kimura, I Nakamichi, S Akifusa, K Goto, A Yoshida, R Fujisawa, K Sonoki, T Nishihara
    • Publisher
      InTech
    • Related Report
      2011 Final Research Report
  • [Book] Association between tooth loss and cancer mortality in elderly individuals.2012

    • Author(s)
      Ansai T, Takata Y
    • Publisher
      InTech
    • Related Report
      2011 Final Research Report
  • [Book] Association of Disease-Specific Mortality with Physical Fitness Measurements and Nonparticipation in an 80-Year-Old Population. In : Geriatrics2012

    • Author(s)
      Takata Y, Ansai T, etal
    • Total Pages
      24
    • Publisher
      InTech
    • Related Report
      2011 Annual Research Report
  • [Book] 必修臨床研修歯科医ハンドブック.竹原直道、廣藤卓雄監修、粟野秀慈編集、医歯薬出版、20102010

    • Author(s)
      高田豊
    • Publisher
      臨床検査値の見方
    • Related Report
      2010 Annual Research Report
  • [Book] Effects of chewing ability on longevity2009

    • Author(s)
      Ansai T, Takata Y, Takehara T
    • Publisher
      Nova Science Publishers
    • Related Report
      2011 Final Research Report
  • [Book] Effects of chewing ability on longevity. In: Handbook on Longevity: Genetics, Diet & Disease2009

    • Author(s)
      Ansai T, Takata Y, Takehara T
    • Publisher
      Nova Science Publishers, Inc.
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://naika.kyu-dent.ac.jp//labo/

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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