| Co-Investigator(Kenkyū-buntansha) |
NOMURA Yoshiaki 鶴見大学, 歯学部, 准教授 (90350587)
IMAI Susumu 鶴見大学, 歯学部, 講師 (80072958)
NAKAMURA Yoshiki 鶴見大学, 歯学部, 教授 (10097321)
YAMANE Akira 鶴見大学, 歯学部, 教授 (20166763)
SATO Keita 鶴見大学, 歯学部, 准教授 (00280975)
|
|---|
| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2011: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2009: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
|
|---|
| Research Abstract |
The periodontal ligament(PDL) fibroblasts have been suggested as multipotent cells. Periodontal ligament fibroblasts differentiate into osteoblasts and cementoblasts. We established HPDL-iPS cells from the human periodontal ligament(HPDL) fibroblasts. However, in this study, we observed several abnormal karyotype in HPDL-iPS cells. We also observed immature cells in the teratoma. Further study is necessary to clarify the propensity of HPDL-iPS cells to differentiate and to explore safety issues.
|
