| Project/Area Number |
21390581
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical nursing
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| Research Institution | International University of Health and Welfare (2010-2011)
Yokohama City University (2009) |
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Principal Investigator |
YAMAMOTO Keiko 国際医療福祉大学, 保健医療学部, 教授 (70269380)
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| Co-Investigator(Kenkyū-buntansha) |
MATOBA Motohiro 国立がん研究センター, 研究所, 助手 (20199904)
MURAKAMI Satoshi 国立がん研究センター, 研究所, 助手 (70327427)
KAMEISHI Chisono 国際医療福祉大学, 保健医療学部, 助教 (90376202)
KASUGAI Kunio 愛知医科大学, 医学部, 教授 (80298570)
MIZUNO Mari 愛知医科大学, 医学部, 講師 (20351124)
IWASE Satoshi 東京大学, 医学部附属病院・緩和ケア診療部, 副部長 (60372372)
黒田 佑次郎 東京大学, 医学部附属病院・緩和ケア診療部, 特任研究員 (50538783)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2010: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2009: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
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| Keywords | がん看護 / がん疼痛 / 心電図電位変動 / 疼痛定量評価 / がん性疼痛 |
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| Research Abstract |
The ultimate goal of our research is to establish a method to confirm pain relief in inpatients who do not complain of pain. Towards this goal, here we confirmed the feasibility of wavelet analysis of ECG voltage fluctuation as an objective evaluation method of pain in cancer inpatients who did complain of pain. In this pilot study, 8 inpatients with cancer pain underwent a subjective evaluation of pain using a visual analogue scale(VAS) or numerical rating scale(NRS) and subsequently an objective evaluation involving analysis of ECG voltage fluctuations. In particular, it was evaluated whether the objective method could be an effective aid in the diagnosis of the degree of pain. The power amplitudes of ECG voltage fluctuations were found to be correlated with VAS or NRS scores in the same period with pain in all 8 cancer inpatients without motion artifacts. Moreover, the power amplitudes of these fluctuations, VAS score, and NRS score were significantly reduced after administration of a rescue dose of opioid in 5 of the patients without motion artifacts. Power spectral analysis of ECG voltage fluctuations is a promising method to evaluate the degree of pain in cancer inpatients.
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