Development of diagnostic methods for domestic animals infected with larval taeniid cestodes and application to risk management.

• Project/Area Number: 21406009
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Parasitology (including Sanitary zoology)
• Research Institution: Kyoto University (2010-2011); Tottori University (2009)
• Principal Investigator: OKAMOTO Munehiro 京都大学, 霊長類研究所, 教授 (70177096)
• Co-Investigator(Kenkyū-buntansha): ITO Akira 旭川医科大学, 医学部, 教授 (70054020) ; ITO Akira 旭川医科大学, 医学部, 講師 (40312459)
• Co-Investigator(Renkei-kenkyūsha): OKAMOTO Yoshiharu 鳥取大学, 農学部, 教授 (50194410)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000); Fiscal Year 2011: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2010: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000); Fiscal Year 2009: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
• Keywords: 嚢虫症 / テニア症 / 中間宿主 / 家畜 / 個体識別 / リスク評価 / 分子疫学調査

Research Abstract

Parasitological survey on human taeniid cestods was don in Tibetan Plateau, Sichuan, China and Bali, Indonesia. In Tibetan Plateau, three human Taenia, Taenia solium, Taenia saginata and Taenia asiatica were endemic sympatorically. In Bali, T. solium was endemic in the northern part of island a d T. saginata was endemic in the southern part. In addition, hybrid between T. saginata and T. asiatica was found in Tibetan Plateau. We examined the molecul ar and immunological diagnostic methods for human taniasis/cysticercosis, which were developed by our research group. We also evaluated the risk of domestic animals for endemic of human taniasis/cysticercosis.

Research Products

• [Journal Article] An ocular cysticercosis in Bali, Indonesia caused by Taenia solium Asian genotype (2012)
  • Author(s): Swastika K, Dewiyani CI, Yanagida T, Sako Y, Sudarmaja M, Sutisna P, Wandra T, Dharmawan NS, Nakaya K, Okamoto M, Ito A
  • Journal Title: Parasitology International Volume: 61(2) Pages: 378-380
  • URL: http://dx.doi.org/10.1016/j.parint.2011.11.004
  • Peer Reviewed
• [Journal Article] Molecular identification of unilocular hydatid cysts from domestic ungulates in Ethiopia (2012)
  • Author(s): Hailemariam Z, Nakao M, Menkir S, Lavikainen A, Yanagida T, Okamoto M, Ito A
  • Journal Title: Parasitology International Volume: 61(2) Pages: 375-377
  • URL: http://dx.doi.org/10.1016/j.ympev.2011.07.022
  • Peer Reviewed
• [Journal Article] Recent hybridization between Taenia asiatica and Taenia saginata (2012)
  • Author(s): Yamane K, Suzuki Y, Tachi E, Li T, Chen X, Nakao M, Nkouawa A, Yanagida T, Sak Y, Ito A, Sato H, Okamoto M
  • Journal Title: Parasitology International Volume: 61(2) Pages: 351-355
  • URL: http://dx.doi.org/10.1016/j.parint.2012.01.005
  • Peer Reviewed
• [Journal Article] A Phylogenetic relationships within Echinococcus and Taenia tapeworms(Cestoda : Taeniidae) (2012)
  • Author(s): Knapp J, Nakao M, Yanagida T, Okamoto M, Saarma U, Lavikainen A, Ito
  • Journal Title: Molecular Phylogenetics and Evolution Volume: 61(3) Pages: 628-638
  • URL: http://dx.doi.org/10.1016/j.ympev.2011.07.022
  • Peer Reviewed
• [Journal Article] Recent hybridization between Taenia asiatica and Taenia saginata (2012)
  • Author(s): Yamane K, Suzuki Y, Tachi E, Li TY, Chen XW, Nakao M, Nkouawa A, Yanagida T, Sako Y, Ito A, Sato H, Okamoto M.
  • Journal Title: Parasitol Int Volume: 61 Issue: 2 Pages: 351-355
  • DOI: 10.1016/j.parint.2012.01.005
  • Peer Reviewed
• [Journal Article] Taeniasis/Cyatice rcosis in Bali, Indonesia (2011)
  • Author(s): Wandra T, Sudewi AAR, Swastika K, Sutisna P, Dharmawan NS, Yulfi H, Darlan DM, I Kapti N, Samaan G, Sato MO, Okamoto M, Sako Y, Ito A
  • Journal Title: Southeast Asian Journal of Tropical Medicine and Public Health Volume: 42(4) Pages: 793-802
  • Peer Reviewed
• [Journal Article] The first workshop towards the control of cestode zoo noses in Asia and Africa (2011)
  • Author(s): Ito A, Okamoto M, Li T, Wandra T, Dharmawan NS, Swastika K, Dekumyoy P, Kusolsuk T, Davvajav A, Davaasuren A, Dorjsuren T, Mekonnen1 SM, Negasi ZH, Yanagida T, Sako Y, Nakao M, Nakaya K, Lavikainen AJ, Nkouawa A, Mohammadzadeh T
  • Journal Title: Parasites & Vector Volume: 4 Pages: 114-114
  • URL: http://dx.doi.org/10.1186/1756-3305-4-114
  • Peer Reviewed
• [Journal Article] Phylogenetic relationships within Echinococcus and Taenia tapeworms (Cestoda: Taeniidae): an inference from nuclear protein-coding genes (2011)
  • Author(s): Knapp J, Nakao M, Yanagida T, Okamoto M, Saarma U, Lavikainen A, Ito A.
  • Journal Title: Molecular Phylogenetics and Evolution Volume: 61 Issue: 3 Pages: 628-638
  • DOI: 10.1016/j.ympev.2011.07.022
  • Peer Reviewed
• [Journal Article] The first workshop towards the control of cestode zoonoses in Asia and Africa (2011)
  • Author(s): Ito A, et al.
  • Journal Title: Parasites and Vectors Volume: 4:114 Issue: 1 Pages: 1-6
  • DOI: 10.1186/1756-3305-4-114
  • Peer Reviewed
• [Journal Article] Taeniasis/Cyaticercosis in Bali, Indonesia (2011)
  • Author(s): Wandra T, Sudewi AAR, Swastika K, Sutisna P, Dharmawan NS, Yulfi H, Darlan DM, I Kapti N, Samaan G, Sato MO, Okamoto M, Sako Y, Ito A
  • Journal Title: Southeast Asian J Trop Med Public Health Volume: 42 Pages: 793-802
  • Peer Reviewed
• [Journal Article] Molecular and serological survey on taenias is and cysticercosis in Kanchanaburi Province, Thailand (2010)
  • Author(s): Anantaphruti MT, Okamoto M, Yoonuan T, Saguankiat S, Kusolsuk T, Sato M, Sato MO, Sako Y, Waikagul J, Ito A
  • Journal Title: Parasitology International Volume: 59 Pages: 326-330
  • Peer Reviewed
• [Journal Article] State-of-the-art Echinococcus and Taenia : Phylogenetic taxonomy of human-pathogenic tapeworms and its application to molecular diagnosis (2010)
  • Author(s): Nakao M, Yanagida T, Okamoto M, Knapp J, Nkouawa A, Sako Y, Ito A
  • Journal Title: Infection, Genetics and Evolution Volume: 10 Pages: 444-452
  • Peer Reviewed
• [Journal Article] Evidence of hybridization between Taenia saginata and Taenia asiat ica (2010)
  • Author(s): Okamoto M, Nakao M, Blair D, Anantaphruti M T, Jitra Waikagul J, Ito A
  • Journal Title: Parasitl. Int. Volume: 59 Pages: 70-74
  • NAID: 10029823295
  • Peer Reviewed
• [Journal Article] Molecular and serological survey on taeniasis and cysticercosis in Kanchanaburi Province, Thailand. (2010)
  • Author(s): Anantaphruti MT, Okamoto M, Yoonuan T, Saguankiat S, Kusolsuk T, Sato M, Sato MO, Sako Y, Waikagul J, Ito A
  • Journal Title: Parasitology International Volume: 59 Pages: 326-330
  • NAID: 10029824854
  • Peer Reviewed
• [Journal Article] State-of-the-art Echinococcus and Taenia : Phylogenetic taxonomy of human-pathogenic tapeworms and its application to molecular diagnosis. (2010)
  • Author(s): Nakao M, Yanagida T, Okamoto M, Knapp J, Nkouawa A, Sako S, Ito A
  • Journal Title: Genetics and Evolution Volume: 10 Pages: 444-452
  • Peer Reviewed
• [Journal Article] Evidence of hybridization between Taenia saginata and Taenia asiatica. (2010)
  • Author(s): Okamotoa M, Nakao M, Blair D, Anantaphruti M T, Jitra Waikagul J, Ito A.
  • Journal Title: Parasitology International 59 Pages: 70-74
  • NAID: 10029823295
  • Peer Reviewed
• [Journal Article] Geographic pattern of genetic variation in the fox tapeworm Echinococcus multilocularis (2009)
  • Author(s): Nakao M, Xia N, Okamoto M, Yanagida T, Sako Y, Ito A
  • Journal Title: Parasitology International Volume: 58 Pages: 384-389
  • NAID: 10027670530
  • Peer Reviewed
• [Journal Article] Phylogenetic relationships of rodent pinworms(genus Syphacia) in Japan inferred from 28S rDNA sequences (2009)
  • Author(s): Okamoto M, Urushima H, Hasegawa H
  • Journal Title: Parasitology International Volume: 58 Pages: 330-333
  • NAID: 10027670245
• [Journal Article] Phylogenetic relationships of rodent pinworms (genus Syphacia) in Japan inferred from 28S rDNA sequences. (2009)
  • Author(s): Okamoto M., Urushima H., Hasegawa H.
  • Journal Title: Parasitology International 58 Pages: 330-333
  • NAID: 10027670245
  • Peer Reviewed
• [Journal Article] Geographic pattern of genetic variation in the fox tapeworm Echinococcus multilocularis. (2009)
  • Author(s): Nakao M., Xia N., Okamoto M., Yanagida T., Sako Y., Ito A
  • Journal Title: Parasitology International 58 Pages: 384-389
  • NAID: 10027670530
  • Peer Reviewed
• [Journal Article] (2009)
  • Author(s): 岡本宗裕
  • Journal Title: 現代実験動物学(朝倉書店、東京) Pages: 92-94
• [Presentation] Hybridization between Taenia asiatica and Taenia status of T.asiatica (2011)
  • Author(s): Munehiro Okaraoto
  • Organizer: Joint International Tropical Medicine Meeting 2011
  • Place of Presentation: Bangkok, Thailand
  • Year and Date: 2011-12-02
• [Presentation] Usefulness of pumpkin seeds combining areca nuts in treatment of community-based screened taeniasis carreiers (2011)
  • Author(s): Li T, Long C, Nakao M, Chen X, Okamoto M, Giraudoux P, Craig PS, Xiao N, Huang L, Ito A
  • Organizer: International Tropical Medicine Meeting
  • Place of Presentation: Bangkok, Thailand
• [Presentation] Taenia and Taeniasis : Epidemiological survey and molecular identification in Tha Song Yang distric (2011)
  • Author(s): Kusolsuk T, Dekumyoy P, Chaisiri K, Sanguankiat S, Okamoto M, Yanagida T, Sako Y, Komalanisra C, Ito A
  • Organizer: Joint International Tropic al Medicine Meeting
  • Place of Presentation: Bangkok, Thailand
• [Presentation] Current situation of taeniasis and cysticercosis in Bali, Indonesia (2011)
  • Author(s): Swastica K, Wandra T, Sudarmaja M, Dharmawan NS, Sako Y, Yanagida T, Okamoto M, Sutisna P, Ito A
  • Organizer: Joint International Tropical Medicine Meeting
  • Place of Presentation: Bangkok, Thailand
• [Presentation] Hybridization between Taenia asiatica and Taenia saginata and taxonomici status of T (2011)
  • Author(s): Okamoto M
  • Organizer: asiatica. Joint International Tropical Medicine Meeting
  • Place of Presentation: Bangkok, Thailand
• [Presentation] The present knowledge on Taenia asiatica and Taenia saginata : Evidence of hybrids. (2010)
  • Author(s): Munehiro Okamoto
  • Organizer: Joint International Tropical Medicine Meeting 2010
  • Place of Presentation: Bangkok, Thailand
  • Year and Date: 2010-12-03
• [Presentation] The present knowledge on Taenia asiatica and Taenia saginata : Evidence of hybrids (2010)
  • Author(s): Okamoto M
  • Organizer: Joint International Tropi cal Medicine Meeting
  • Place of Presentation: Bangkok, Thailand
• [Presentation] Cross-fertilization and hybridization in Taenia species. (2009)
  • Author(s): Okamotoa M
  • Organizer: 6th Seminar on Food- and Water-borne Parasitic Zoonoses
  • Place of Presentation: Bangkok, Thailand
  • Year and Date: 2009-12-04
• [Presentation] Cross-fertilization and hybridization in Taenia species (2009)
  • Author(s): Okamoto M
  • Organizer: 6th Seminar on Food-and Water-borne Parasitic Zoo noses
  • Place of Presentation: Bangkok, Thailand