Exploration of regionality in laboratory test results and derivation of common reference intervals through international collaborative survey
| Project/Area Number |
21406015
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Laboratory medicine
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NOJIMA Junzo 山口大学, 大学院・医学系研究科, 教授 (30448071)
SHIMIZU Yoshihisa 山口大学, 大学院・医学系研究科, 助教 (80403674)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2011: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2009: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
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| Keywords | 基準範囲 / 東南アジア / 標準化 / 多施設共同研究 / 地域差 / 臨床検査値変動要因 / パネル血清 / 海外学術調査 / 枝分かれ分散分析 / 地域差分析 / 臨床化学検査 / イムノアッセイ / クロスチェック / 生理的変動 / 国際連携 / 多変量解析 / IFCC |
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| Research Abstract |
An international multi-center study on reference values was conducted in 2009 with participation of 62 laboratories in South-east Asia. 3541 well-defined healthy individuals(Japan 2082 ; oversea 1459) were recruited. All sera were measured collectively for 72 commonly measured analytes in Japan. Regionality of test results was observed in 22 analytes, but it was not when data were limited to those from Japan. A variety of evidence on sources of variations was analyzed based on life style questionnaire. With successful outcome, an expanded study of a global scale was planned and launched with elaboration of common protocol in 2011.
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Report
(4 results)
Research Products
(24 results)
