Researches on the statistical power of the likelihood ratio test in the cohort-based nested case-control data analyses
| Project/Area Number |
21500279
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Statistical science
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| Research Institution | Oita University |
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Principal Investigator |
IZUMI Shizue 大分大学, 工学部, 准教授 (70344413)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKACHI Kei 放射線影響研究所, 顧問 (00142117)
FUJII Yoshinori 宮崎大学, 教育文化学部, 教授 (10218985)
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| Research Collaborator |
COLOGNE John 放射線影響研究所, 統計部, 顧問
TANAKA Sachiko 京都大学, EBM研究センター, 助教
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 医薬生物 / ゲノム統計解析 / 分子疫学 / 疫学 / 計量生物 / 医薬生物統計 / コホート研究 / 症例対照研究 / サンプリング / マッチング / カウンターマッチング / 検出力 |
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| Research Abstract |
We proposed a statistical method to calculate the statistical power of the likelihood ratio test for the statistical models of causal inference with genetic and environmental factors in the analyses of the cohort-based nested case-control data. And we developed an application of our proposed method in the statistical analysis system R to increase the usage of our proposed method. Further we evaluated the characteristics of our proposed method through the numerical experiments using some sample data sets on molecular epidemiologic studies. Therefore these achievements assist in increasing some efficiency of the molecular epidemiologic researches.
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Report
(4 results)
Research Products
(58 results)
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[Presentation] Effects of radiation on serum risk markers of breast cancer found in healthy A-bomb survivors2010
Author(s)
Grant E, Neriishi K, Cologne J, Eguchi H, Hayamshi T, Geyer S, Izumi S, Nishi N, Land C, Sharp GB, Nakachi K
Organizer
Joint scientific meeting of the international epidemiological association western pacific region and the Japan epidemiological association
Place of Presentation
埼玉県立大学
Related Report
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