| Project/Area Number |
21500297
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Tohoku University (2011)
The University of Aizu (2009-2010) |
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Principal Investigator |
WEI Daming 東北大学, 大学院・医学系研究科, 非常勤講師 (20306434)
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| Co-Investigator(Kenkyū-buntansha) |
OKAZAKI Osamu 独立行政法人国立国際医療センター, 病院, 医長 (30203970)
ZHU Xin 公立大学法人会津大学, コンピュータ理工学部, 准教授 (70448645)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | Brugada症候群 / Brugada型心電図 / 導出心電図 / 付加誘導心電図 / 特発性心室細動 / Brugada症候 |
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| Research Abstract |
A new diagnostic aid of Brugada syndrome using synthesized ECGs on additional leads is developed. Major research activities included development of algorithm to synthesize ECGs on additional leads one size above standard chest leads from 12-lead ECG, computer simulation of Brudaga type electrocardiograms, collection of ECG clinical data, as well as investigation of clinical effect of the synthesized ECGs. A paper, Computer Simulation of Atypical Brugada Syndrome published in Journal of Electrocardiology reproduced tipical and atypical Brudaga type electrocardiogram, which gave most realistic simulation result of Brudaga type electrocardiogram. This paper was selected to appear on the front page of the issue, giving an evidence of the impact of this study. We recently recorded a number of clinical Brudaga type electrocardiograms with both the 12-lead and additional leads ECGs, which is quite valuable for clinical study and new results based on these data are expected in the near future
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