| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
The specific aim of this study is focused on disclosing of pathological changes, if any, causing intractable epilepsy. Both of abnormal deposit of iron granules in the astrocytes and abnormal immunohistochemial expression of glutamate transporter of glia type were observed in normal-looking area around organic lesions, taken from epileptogenic cortices by neurosurgical procedures. Those findings strongly suggest a possibility that dysfunction of the astrocytes causes epilepsy.
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