Quantitative trait locus analysis using Y chromosome consomic mouse strains

Research Project

Project/Area Number	21500393
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Laboratory animal science
Research Institution	National Institute of Agrobiological Sciences
Principal Investigator	SUTO Jun-ichi 独立行政法人農業生物資源研究所, 家畜ゲノム研究ユニット, 上級研究員 (60355740)
Project Period (FY)	2009 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	量的形質 / Y染色体 / コンソミックマウス系統 / コンソミックマウス / 精巣重量 / 体重・肥満 / 関連解析 / 量的形質遺伝子座
Research Abstract	We identified several SNPs and gene polymorphisms that were significantly associated with testis weight in Y-consomic strains. In addition, we showed that the Y chromosome of the inbred mouse KK/Ta strain was associated with reduced body size in Y-consomic strains.