Development of a novel healing system for bone disease using a synergetic effect of magnetic fields and bone-regulating hormone

• Project/Area Number: 21500404
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Kanazawa University
• Principal Investigator: SUZUKI Nobuo 金沢大学, 環日本海域環境研究センター, 准教授 (60242476)
• Co-Investigator(Kenkyū-buntansha): YAMADA Sotoshi 金沢大学, 環日本海域環境研究センター, 教授 (80019786) ; TABUCHI Yoshiaki 富山大学, 生命科学先端研究センター, 准教授 (20322109) ; WADA Shigehito 富山大学, 附属病院, 講師 (50303219)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 骨芽細胞 / 破骨細胞 / 極低周波磁場 / ホルモンとの相互作用 / ウロコ / ラットの頭蓋骨 / メラトニン / 変動磁場 / 再生モデル / in vivoの解析 / 骨再生モデル

Research Abstract

To develop a novel healing system for bone disease using magnetic fields, we examined the effects of extremely low-frequency(ELF) magnetic fields(60Hz) on osteoblasts and osteoclasts of goldfish scales using in vitro assay systems. The osteoblasts and osteoclasts in goldfish scales responded sensitively to the ELF magnetic fields in an in vitro experiment. The results agreed with those of rat calvarial osteoblasts and osteoclasts. In addition, the synergetic effect of magnetic fields and a bone-regulating hormone, melatonin, was confirmed. Thus, we succeeded in creating a novel healing system for bone disease by magnetic fields.

Research Products

• [Journal Article] Expression of osteoblast-specific genes during spontaneous goldfish scale regeneration and role of cell-to-cell contact in controlling the onset of resorption/regeneration process found in intra-scalepocket autotransplantation of modified scales (2012)
  • Author(s): Thamamongood, T. A, Furuya, R., Fukuba, S., Nakamura, M., Suzuki, N. andHattori, A
  • Journal Title: Bone Pages: 1240-1249
  • Peer Reviewed
• [Journal Article] Cloning of two members of the calcitonin receptor family from stingray (2012)
  • Author(s): Suzuki, N., Sekiguchi, T., Satake, H., Kato, K., Nishiyama, Y., Takahashi, H., Danks, J. A., Martin, T. J., Hattori, A., Nakano, M., Kakikawa, M., Yamada, S., (他8名)
  • Journal Title: Gene Volume: 499 Pages: 90-95
  • Peer Reviewed
• [Journal Article] Expression of osteoblast-specific genes during spontaneous goldfish scale regeneration and role of cell-to-cell contact in controlling the onset of resorption/regeneration process found in intra-scalepocket autotransplantation of modified scales (2012)
  • Author(s): Thamamongood, T.A, Furuya, R., Fukuba, S., Nakamura, M., Suzuki, N., Hattori, A.
  • Journal Title: Bone Volume: (in press) Issue: 6 Pages: 1240-1249
  • DOI: 10.1016/j.bone.2012.03.021
  • Peer Reviewed
• [Journal Article] Prostaglandin E2 increases both osteoblastic and osteodastic activities in the scales of goldfish and participates in the calcium metabolism in goldfish (2012)
  • Author(s): Omori, K., Wada, S., Maruyama, Y., Hattori, A., Kitamura, K., Sato, Y., Nara, M., Funahashi, H., Yachiguchi, K., Hayakawa, K., Endo, M., Kusakari, R., Yano, S., Srivastav, A.K., Kusui, T., Ejiri, S., Chen, W., Tabuchi, Y., Furusawa, Y., Hondo, T., Sasayama, Y. Nishiuchi, T., Nakano, M., Sakamoto, T., Suzuki, N.
  • Journal Title: Zool.Sci. Volume: (in press)
  • Peer Reviewed
• [Journal Article] Cloning of two members of the calcitonin-family receptors from stingray, Dasyatis akajei Possible physiological roles of the calcitonin family in osmoregulation (2012)
  • Author(s): Suzuki N, Sekiguchi T, Satake H, Kato K, Nishiyama Y, Takahashi H, et al
  • Journal Title: Gene Volume: 499 Issue: 2 Pages: 326-331
  • DOI: 10.1016/j.gene.2012.03.042
  • Peer Reviewed
• [Journal Article] Parathyroid hormone 1 (1-34) acts on the scales and involves calcium metabolism in goldfish (2012)
  • Author(s): Suzuki, N., Danks, J.A., Maruyama, Y., Ikegame, M., Sasayama, Y., Hattori, A., Nakamura, M., Tabata, M.J., Yamamoto, T., Furuya, R., Saijoh, K., Mishima, H., Srivastav, A.K., Furusawa, Y., Kondo, T., Tabuchi, Y., Takasaki, I., Chowdhury, V.S., Hayakawa, K. and Martin T.J.
  • Journal Title: Bone Volume: 48 Issue: 5 Pages: 1186-1193
  • DOI: 10.1016/j.bone.2011.02.004
  • NAID: 120003020733
  • Peer Reviewed
• [Journal Article] Parathyroid hormone 1(1-34) acts on the scales and involves calcium metabolism in goldfish (2011)
  • Author(s): Suzuki, N., (他19名)
  • Journal Title: Bone Volume: 48 Pages: 1186-1193
  • NAID: 120003020733
  • Peer Reviewed
• [Journal Article] 自動面積測定法によるキンギョのウロコを骨のモデルとしたアッセイ法の改良 (2011)
  • Author(s): 北村敬一郎, 中野淳, 川部季美, 早川和一, 根本鉄, 大嶋雄治, 島崎洋平, 服部淳彦, 鈴木信雄
  • Journal Title: 日本海域研究 Volume: 42 Pages: 27-34
  • Peer Reviewed
• [Journal Article] Effects of inorganic mercury on osteoclasts and osteoblasts of the goldfish scales in vitro (2011)
  • Author(s): Suzuki, N., Yachiguchi, K., Hayakawa, K., Omori, K., Takada, K., Tabata, J.M., Kitamura, K., Endo, M., Wada, S., Srivastav, A.K., Chowdhury, V.S., Oshima, Y., Hattori, A.
  • Journal Title: J.Fac.Agr., Kyushu Univ. Volume: 56 Pages: 47-51
  • NAID: 120003025271
  • Peer Reviewed
• [Journal Article] Tributyltin-binding protein type 1, a lipocalin, prevents inhibition of osteoblastic activity by tributyltin in fish scales (2011)
  • Author(s): Satone, H., Lee, J.M., Oba, Y., Kusakabe, T., Akahoshi, E., Miki, S., Suzuki, N., Sasayama, Y., Nassef, M., Shimasaki, Y., Kawabata, S., Honjo, T., Oshima, Y.
  • Journal Title: Aquatic Toxicol Volume: 103 Issue: 1-2 Pages: 79-84
  • DOI: 10.1016/j.aquatox.2011.02.009
  • Peer Reviewed
• [Journal Article] メラトニンの新規作用:骨に対する作用とその誘導体を用いた骨疾患治療薬の開 (2011)
  • Author(s): 鈴木信雄, 関あずさ, 染井正徳, 中村正久, 矢野幸子, 大森克徳, 池亀美華, 三島弘幸, 早川和一, 服部淳彦
  • Journal Title: 比較内分泌学 Volume: 37 Pages: 194-203
• [Journal Article] Acceleration-based study of optimum exercise for human weight-bearing bones enhancement. (2011)
  • Author(s): Kitamura, K., Chen, W., Zhu, X., Suzuki.N., Yano, S., Nemoto, T.
  • Journal Title: Biol.Sci.Space Volume: 24 Pages: 83-90
  • NAID: 10027810977
  • Peer Reviewed
• [Journal Article] Parathyroid hormone 1 (1-34) acts on the scales and involves calcium metabolism in goldfish (2011)
  • Author(s): Suzuki, N., Danks, JA., Maruyama, Y., Sasayama, Y., Hattori, A., Ikegame, M., Nakamura, M., Tabata, M.J., Yamamoto, T., Furuya, R., Saijoh, K., Mishima, H., Srivastav, A.K., Furusawa, Y., Kondo, T., Tabuchi, Y., Takasaki, I., Chowdhury, VS., Hayakawa, K., Martin T.J.
  • Journal Title: Bone Volume: 48 Pages: 1186-1193
  • NAID: 120003020733
  • Peer Reviewed
• [Journal Article] Osteoblas tactivity in the goldfish scale responds sensitively to mechanical stress (2010)
  • Author(s): Kitamura, K., Suzuki, N., Sato, Y., Nemoto, T., Ikegame, M., Yamamoto, T., Shimizu, N., Kondo, T., Furusawa, Y., Wada, S.
  • Journal Title: Comp. Biochem. Physiol. Volume: 156 Pages: 357-363
  • Peer Reviewed
• [Journal Article] Osteoblast activity in the goldfish scale responds sonsitively to mechanical stress. (2010)
  • Author(s): Kitamura, K., Suzuki, N., Sato, Y., Nemoto, T., Ikegame, M., Yamamoto, T., Shimizu, N., Kondo, T., Furusawa, Y., Wada.S., Hattori, A.
  • Journal Title: Comp.Biochem.Physiol., part A Volume: 156 Pages: 357-363
  • Peer Reviewed
• [Journal Article] 歯の象牙質における成長線の周期性と生物リズムとの関連 : メラトニンによる調節の可能性 (2010)
  • Author(s): 三島弘幸, 北原正大, 服部淳彦, 鈴木信雄, 田畑純, 奈良雅之, 箆光男, 見明康夫
  • Journal Title: 比較内分泌学 Volume: 36 Pages: 106-112
  • NAID: 10026467334
  • Peer Reviewed
• [Journal Article] Osteoblast activity in the goldfish scale responds sensitively to mechanical stress (2010)
  • Author(s): Kitamura, K., Suzuki, N., Sato, Y., Nemoto, T., Ikegame, M., Yamamoto, T., Shimizu, N., Kondo, T., Furusawa, Y., Wada, S., Hattori, A.
  • Journal Title: Comp.Biochem.Physiol., part A (in press)
  • Peer Reviewed
• [Journal Article] Diurnal expressions of four subtypesof melatonin receptor genes in the optictectum and retina of goldfish (2009)
  • Author(s): Ikegami, T., Azuma, K., Nakamura, M., Suzuki, N., Hattori, A. and Ando, H
  • Journal Title: Comp. Biochem. Physiol. Volume: 152 Pages: 219-224
  • Peer Reviewed
• [Journal Article] The depressive effects of 5,8,11-eicosatrienoic acid (20:3n-9) on osteoblasts (2009)
  • Author(s): Hamazaki, T., Suzuki, N., Widyowati, R., Miyahara, T., Kadota, S., Ochiai, H., Hamazaki, K.
  • Journal Title: Lipids 44 Pages: 97-102
  • Peer Reviewed
• [Journal Article] Diurnal expressions of four subtypes of melatonin receptor genes in the optictectum and retina of goldfish (2009)
  • Author(s): Ikegamia, T., Azuma, K., Nakamura, M., Suzuki, N., Hattori, A., Ando, H.
  • Journal Title: Comp.Biochem.Physiol., Part A 152 Pages: 219-224
  • Peer Reviewed
• [Journal Article] Calcitonin in a protochordate, Ciona intestinalis : the prototype of the vertebrate Calcitonin/Calcitonin gene related peptide superfamily (2009)
  • Author(s): Sekiguchi, T., Suzuki, N., Fujiwara, N., Aoyama, M., Kawada, T., Sugase, K., Murata, Y., Sasayama, Y., Ogasawara, M., Satake, H.
  • Journal Title: FEBS J. 276 Pages: 4437-4447
  • Peer Reviewed
• [Presentation] Activation of osteoclasts in female goldfish during the reproductive stage (2012)
  • Author(s): Maruyama, Y., Suzuki, N., Hattori, A
  • Organizer: 7^<th> Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel(Malaysia)
• [Presentation] Activation of osteoclasts in female goldfish during the reproductive stage (2012)
  • Author(s): Maruyama, Y., Suzuki, N., Hattori, A.
  • Organizer: 7th Congress of the Asia and Oceania Society for Comparative Endocrinology
  • Place of Presentation: Sunway Resort Hotel, Malaysia
• [Presentation] キンギョの再生ウロコのin vivoおよびin vitro系による機械的刺激の骨代謝への影響 (2011)
  • Author(s): 佐藤雄亮,根本鉄,鈴木信雄,矢野幸子,服部淳彦,北村敬一郎
  • Organizer: 平成23年度生体医工学会北陸支部大会
  • Place of Presentation: 金沢大学サテライトプラザ(石川県)
  • Year and Date: 2011-12-10
• [Presentation] 赤外・ラマン分光によるキンギョのウロコの状態分析 (2011)
  • Author(s): 奈良雅之,服部淳彦,大西晃宏,赤塚陽子,鈴木信雄,松田准一
  • Organizer: 医用分光学研究会
  • Place of Presentation: 島根大学(島根県)
  • Year and Date: 2011-11-13
• [Presentation] 赤外・ラマン分光によるキンギョのウロコの状態分析 (2011)
  • Author(s): 奈良雅之, 服部淳彦, 大西晃宏, 赤塚陽子, 鈴木信雄, 松田准一
  • Organizer: 医用分光学研究会
  • Place of Presentation: 島根大学、島根県(招待講演)
  • Year and Date: 2011-11-13
• [Presentation] 魚類のウロコにおけるホルモン及び物理的刺激(磁場刺激)の応答 (2011)
  • Author(s): 鈴木信雄
  • Organizer: 日本歯科基礎医学会サテライトシンポジウム
  • Place of Presentation: 朝日大学(岐阜県)
  • Year and Date: 2011-09-30
• [Presentation] 魚類のウロコにおけるホルモン及び物理的刺激(磁場刺激)の応答 (2011)
  • Author(s): 鈴木信雄
  • Organizer: 日本歯科基礎医学会
  • Place of Presentation: 長良川国際会議場、岐阜県(招待講演)
  • Year and Date: 2011-09-30
• [Presentation] 骨とメラトニン (2011)
  • Author(s): 服部淳彦,池亀美華,矢野幸子,鈴木信雄
  • Organizer: 第3回抗加齢内分泌研究会学術集会
  • Place of Presentation: 鶴見大学会館(神奈川県)
  • Year and Date: 2011-09-04
• [Presentation] 骨とメラトニン (2011)
  • Author(s): 服部淳彦, 池亀美華, 矢野幸子, 鈴木信雄
  • Organizer: 第3回抗加齢内分泌研究会学術集会
  • Place of Presentation: 鶴見大学会館、神奈川県(招待講演)
  • Year and Date: 2011-09-04
• [Presentation] 新規ブロモメラトニン誘導体の骨折治癒モデルラットの骨代謝に及ぼす影響 (2011)
  • Author(s): 関あずさ, 鈴木信雄, 池亀美華, 染井正徳, 服部淳彦
  • Organizer: 第31回日本骨形態計測学会
  • Place of Presentation: 長良川国際会議場、岐阜県
• [Presentation] 新規ブロモメラトニン誘導体の骨折治癒モデルラットの骨代謝に及ぼす影響 (2011)
  • Author(s): 関あずさ, 鈴木信雄, 染井正徳, 矢野幸子, 服部淳彦
  • Organizer: 第29回日本骨代謝学会
  • Place of Presentation: 大阪国際会議場、大阪府
• [Presentation] 物理的刺激に対するメダカのウロコの骨芽及び破骨細胞の応答 (2011)
  • Author(s): 矢野幸子, 大森克徳, 佐藤雄亮, 北村敬一郎, 丸山雄介, 中野真樹, 服部淳彦, 池亀美華, 鈴木信雄
  • Organizer: 第25回日本宇宙生物科学会
  • Place of Presentation: 横浜国立大学教育文化ホール、神奈川県
• [Presentation] 魚類の再生ウロコの骨代謝に及ぼす機械的刺激の影響:in vivoおよびin vitroのアッセイによる解析 (2011)
  • Author(s): 佐藤雄亮, 根本鉄, 鈴木信雄, 矢野幸子, 服部淳彦, 北村敬一郎
  • Organizer: 第25回日本宇宙生物科学会
  • Place of Presentation: 横浜国立大学教育文化ホール、神奈川県
• [Presentation] 交流磁場の骨形成促進作用 : 再生ウロコを用いたin vivoの解析 (2010)
  • Author(s): 鉋杢賃墾, 柿川真紀子, 幽衷, 坦遡圭童, 高崎一朗, 古澤之裕, 近藤隆, 和田重人, 廣田憲之, 北村敬一郎, 岩坂正和, 服部淳彦, 上野照剛
  • Organizer: 平成22年度宇宙生物科学会
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2010-09-17
• [Presentation] 加速度計測に基づく過重負荷骨形成のための最適運動 (2010)
  • Author(s): 北村敬一郎, 陳文西, 朱欣, 鈴木信雄, 矢野幸子, 根本鉄
  • Organizer: 平成22年度宇宙生物科学会
  • Place of Presentation: 東北大学(宮城県)
  • Year and Date: 2010-09-07
• [Presentation] The relationship between the melatonin and the periodicity of incremental lines in the tooth dentin. (2010)
  • Author(s): Kitahara, M., Hattori, A., Suzuki.N., Tabata, M.J., Kakei, M., Miake, Y., Mishima, H.
  • Organizer: 37th European Symposium on Calcified Tissues
  • Place of Presentation: Glasgow(United Kingdom)
  • Year and Date: 2010-06-26
• [Presentation] Scale metabolite profiling reveals differential changes in response to gravitational stress. (2010)
  • Author(s): Maeda, M., Hayashi, A., Nakamura, S., Serino, T., Kitamura, K., Suzuki.N.
  • Organizer: 58 th ASMS Conference on Mass Spectrometry and Allied Topics
  • Place of Presentation: Salt Lake City, Utah(USA)
  • Year and Date: 2010-05-23
• [Presentation] 磁場による骨形成作用:ウロコを用いた解析 (2010)
  • Author(s): 鈴木信雄
  • Organizer: バイオサイエンスシンポジウム
  • Place of Presentation: 金沢大学(石川県)
  • Year and Date: 2010-02-24
• [Presentation] 磁場による骨形成作用 : ウロコを用いた解析 (2010)
  • Author(s): 鈴木信雄
  • Organizer: バイオサイエンスシンポジウム
  • Place of Presentation: 金沢大学 (石川県)
  • Year and Date: 2010-02-24
• [Presentation] Fish Scales : Investigation of the osteoclastic and osteoblastic responses to microgravity using goldfish scales (2010)
  • Author(s): 鈴木信雄
  • Organizer: Prelim Increment 23-24 Science symposium
  • Place of Presentation: JAXA (Ibaraki, Japan)
  • Year and Date: 2010-02-04
• [Presentation] 繁殖期の雌キンギョにおけるカルシウム代謝に対するメラトニンの作用 (2010)
  • Author(s): 丸山雄介,鈴木信雄,伊藤正則,服部淳彦
  • Organizer: 第81回日本動物学会
  • Place of Presentation: 東京大学(東京都)
• [Presentation] 交流磁場の骨形成促進作用:再生ウロコを用いたinvivoの解析 (2010)
  • Author(s): 鈴木信雄,柿川真紀子,山田外史,田渕圭章,高崎一朗,古澤之裕,近藤隆,和田重人,廣田憲之,北村敬一郎,岩坂正和,服部淳彦,上野照剛
  • Organizer: 平成22年度宇宙生物科学会
  • Place of Presentation: 東北大学(宮城県)
• [Presentation] Development andapplication of a fish scale in vitroassay system : Fish scale is a suitablemodel for analysis of bone metabolism (2009)
  • Author(s): Suzuki, N
  • Organizer: 2009 Korea-Japan Joint Research Project Symposium."Aging, Radiation and Environment"
  • Place of Presentation: Pusan National University(Busan, Korea)
  • Year and Date: 2009-12-16
• [Presentation] 象牙質の成長線の形成リズムとメラトニンの分泌リズムとの関連 (2009)
  • Author(s): 三島弘幸, 北原正大, 服部淳彦, 鈴木信雄, 田畑純, 筧光男, 見明康夫
  • Organizer: 第4回バイオミネラリゼーションワークショップ
  • Place of Presentation: 東京大学農学部 (東京都)
  • Year and Date: 2009-12-13
• [Presentation] 魚のウロコをモデル系とした磁場の骨代謝に対する作用 (2009)
  • Author(s): 鈴木信雄
  • Organizer: 日本磁気科学会年会サテライトシンポジウム
  • Place of Presentation: 信州大学(長野県)
  • Year and Date: 2009-11-12
• [Presentation] 魚のウロコをモデル系とした磁場の骨代謝に対する作用 (2009)
  • Author(s): 鈴木信雄
  • Organizer: 日本磁気科学会年会 サテライトシンポジウム
  • Place of Presentation: 信州大学 (長野県)
  • Year and Date: 2009-11-12
• [Presentation] 交流磁場の骨代謝に対する作用:魚鱗を用いたモデル系による解析 (2009)
  • Author(s): 鈴木信雄,柿川真紀子,山田外史,田渕圭章,高崎一朗,古澤之裕,近藤隆,和田重人,廣田憲之,北村敬一郎,岩坂正和,服部淳彦,上野照剛
  • Organizer: 第34回日本比較内分泌学会大会
  • Place of Presentation: 大阪府
  • Year and Date: 2009-10-23
• [Presentation] 交流磁場の骨代謝に対する作用 : 魚鱗を用いたモデル系による解析 (2009)
  • Author(s): 鈴木信雄, 柿川真紀子, 山田外史, 田渕圭章, 高崎一朗, 古澤之裕, 近藤隆, 和田重人, 廣田憲之, 北村敬一郎, 岩坂正和, 服部淳彦, 上野照剛
  • Organizer: 第34回日本比較内分泌学会大会
  • Place of Presentation: 千里ライフサイエンスセンター (大阪府)
  • Year and Date: 2009-10-23
• [Presentation] 繁殖期の雌キンギョにおける破骨細胞の活性化と血漿カルシウム濃度 (2009)
  • Author(s): 丸山雄介, 鈴木信雄, 服部淳彦
  • Organizer: 第34回日本比較内分泌学会大会
  • Place of Presentation: 千里ライフサイエンスセンター (大阪府)
  • Year and Date: 2009-10-23
• [Presentation] Development and application of a fish scale in vitro assay system : Fish scale is a suitable model for analysis of bone metabolism (2009)
  • Author(s): 鈴木信雄
  • Organizer: 2009 Korea-Japan Joint Research Project Symposium. "Aging, Radiation and Environment"
  • Place of Presentation: Pusan National University (Busan, Korea)
  • Year and Date: 2009-10-16
• [Presentation] 魚類のカルシウム代謝におけるウロコの生理学的役割:副甲状腺ホルモンに対する作用 (2009)
  • Author(s): 鈴木信雄
  • Organizer: 宇宙生物科学会第23回大会
  • Place of Presentation: 筑波宇宙センター(茨城県)
  • Year and Date: 2009-10-02
• [Presentation] 魚類のカルシウム代謝におけるウロコの生理学的役割 : 副甲状腺ホルモンに対する作用 (2009)
  • Author(s): 鈴木信雄
  • Organizer: 宇宙生物科学会第23回大会
  • Place of Presentation: 筑波宇宙センター (茨城県)
  • Year and Date: 2009-10-02
• [Presentation] Fish scale is a good model for the evaluation of the bone metabolism in fish : The effects of heavy metals and endocrine disruptors on osteoblasts and osteoclasts in the scales (2009)
  • Author(s): 鈴木信雄
  • Organizer: Busan Symposium in Pukyong National University (JSPS's Asia and Africa Science Platform Program)
  • Place of Presentation: Pukyong National University (Busan, Korea)
  • Year and Date: 2009-06-19
• [Book] 親子判別.『身近な動物を使った実験4』 (2012)
  • Author(s): 服部淳彦, 田畑純, 鈴木信雄
  • Publisher: 三共出版(印刷中)
• [Book] Evolution of calcium homeostasis and its hormonal regulation in vertebrates (2012)
  • Author(s): Suzuki, N., Sakamoto, T.
  • Publisher: Comparative and general aspects of calcium homeostasis and its hormonal regulations. Evolution of calcium homeostasis and its honnonal regulation in vertebrates(in press)
• [Book] 身近な動物を使った実験4(親子判別) (2011)
  • Author(s): 服部淳彦, 田畑純, 鈴木信雄
  • Publisher: 三共出版 印刷中
• [Book] 身近な動物を使った実験1、第3章 キンギョ(鈴木範男編) (2009)
  • Author(s): 鈴木信雄, 田畑純, 服部淳彦
  • Total Pages: 46
  • Publisher: 三共出版
• [Book] Comparative and general aspects of calcium homeostasis and its hormonal regulations. In "Evolution of calcium homeostasis and its hormonal regulation in vertebrates".Virtual special issues in Zoological Science
  • Author(s): Suzuki, N. and Sakamoto, T
• [Book] 第3章親子判別『身近な動物を使った実験4』
  • Author(s): 服部淳彦,田畑純,鈴木信雄
  • Publisher: 三共出版