Development of functional modeling techniques for predicting arrhythmic risk in virtual heart simulation
| Project/Area Number |
21500420
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
NAKAZAWA Kazuo 独立行政法人国立循環器病研究センター, 研究情報基盤管理室, 室長 (50198058)
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| Co-Investigator(Kenkyū-buntansha) |
HARAGUCHI Ryo 国立循環器病研究センター, 研究情報基盤管理室, 研究員 (00393215)
IGARASHI Takeo 東京大学, 大学院・情報学環, 教授 (80345123)
IKEDA Takanori 東邦大学, 医学部, 教授 (80256734)
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| Co-Investigator(Renkei-kenkyūsha) |
NAMBA Tsunetoyo 姫路獨協大学, 医療保健学部, 教授 (70331866)
ASHIHARA Takashi 滋賀医科大学, 医学部, 助教 (80396259)
YAMAGUCHI Takeshi 金沢大学, 医学系, 助教 (60532182)
IJIRI Takashi 理化学研究所, 生物情報基盤構築チーム, 基礎科学特別研究員 (30550347)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | バーチャル心臓 / 不整脈 / 危険予測 / 生物・生体工学 / バーチャル心臟 |
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| Research Abstract |
The result of this research is mainly divided into 1) development of new functional modeling techniques for virtual heart simulation and 2) derivation of results which lead to an arrhythmic risk prediction in virtual heart simulation. As a main result about 1), we issued a news release under the title of "development of beating-heart simulation which can be used easily and quickly on a laptop PC." On the other hand, about 2), we published a paper which verified the hypothesis that the difference between repolarization time of cardiac myocytes in ventricular wall is an important index for the risk prediction of fatal arrhythmia, in virtual heart simulation.
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] 心臓モデリングとコンピュータシミュレーションが導く不整脈研究の世界2010
Author(s)
中沢一雄,原口亮,芦原貴司,難波経豊,戸田直,山口豪,井尻敬,高山健志,五十嵐健夫,倉智嘉久,池田隆徳
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Journal Title
心臓
Volume: 42(4)
Pages: 208-215
NAID
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