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Development of novel methods for diagnosis of skin disorders using multiple acoustic parameters.

Research Project

Project/Area Number 21500451
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionJichi Medical University

Principal Investigator

FUJII Yasutomo  自治医科大学, 医学部, 講師 (00337338)

Co-Investigator(Kenkyū-buntansha) YOSHIZAWA Masasumi  東京都立産業技術高等専門学校, ものづくり工学科, 教授 (40191564)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords超音波組織性状診断 / 音響インピーダンス / 皮膚 / 超音波
Research Abstract

To clarify the potential of a novel system using the acoustic impedance difference imaging(AIDI) method for diagnosis of skin disorders, we used it on a coin, and swine skin. An ultrasound wave with a central frequency of 20 MHz, emitted from a fused quartz rod with a diameter of 1.25 mm, was focused on the surface of the coin and skin samples. The difference in acoustic impedance was determined by the reflection-type interference-based acoustic impedance measurement method. The processed data were produced as grey-scale images on which the maximum measured amplitudes were mapped. We applied the method to a coin. Swine skin, burned and covered with an acrylic board with a thickness of 0.2 mm. All the processed images obtained corresponded almost exactly with the magnified optical ones. In the processed images of swine skin, a marked difference was found after the burning procedure. The processed images obtained using the AIDI method reflected not only the undulations but also other information such as elasticity. In conclusion, our system using AIDI has the potential to become a useful modality for the diagnosis of skin disorders.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (6 results)

All 2012 2011 2010 2009

All Journal Article (2 results) Presentation (4 results)

  • [Journal Article] Processed skin surface images acquired by acoustic impedance difference imaging using the ultrasonic interference method : a pilot study2012

    • Author(s)
      Fujii, Y., Yoshizawa, M., Emoto, R., Haruyama, N., Irie, T., Taniguchi, N.
    • Journal Title

      J Med Ultrasonics

      Volume: 39 Pages: 37-42

    • NAID

      10030380317

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 皮膚用音響インピーダンス差分イメージングシステムの開発2009

    • Author(s)
      川畑宏貴、江本龍二、吉沢昌純、藤井康友、入江喬介
    • Journal Title

      生体医工学シンポジウム

    • Related Report
      2011 Final Research Report
  • [Presentation] Processed skin surface images acquired by acoustic impedance difference imaging using the ultrasonic interference method2011

    • Author(s)
      Fujii, Y., Yoshizawa, M., Emoto, R., Haruyama, N., Irie, T., Taniguchi, N.
    • Organizer
      2011 Congress of the World Federation for Ultrasound in Medicine and Biology
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 超音波干渉法を用いた音響インピーダンス差分イメージングシステムによる皮膚表面画像2010

    • Author(s)
      江本龍二
    • Organizer
      日本超音波医学会第83回学術集会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2010-05-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 超音波干渉法を用いた音響インピーダンス差分イメージングシステムによる皮膚表面画像2010

    • Author(s)
      江本龍ニ、吉澤昌純, 川畑宏貴, 藤井康友, 入江喬介, 谷口信行
    • Organizer
      日本超音波医学会第83回学術集会
    • Place of Presentation
      京都
    • Related Report
      2011 Final Research Report
  • [Presentation] 皮膚用音響インピーダンス差分イメージングシステムの開発2009

    • Author(s)
      川畑宏貴, 江本龍二, 吉沢昌純, 藤井康友, 入江喬介
    • Organizer
      生体医工学シンポジウム2009
    • Place of Presentation
      千葉大学自然科学系総合研究棟1
    • Year and Date
      2009-06-19
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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