| Project/Area Number |
21500471
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
|
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| Research Institution | Teikyo University of Science & Technology (2010-2011)
Hiroshima University (2009) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
DEIE Masataka 広島大学, 大学院・保健学研究科, 教授 (30363063)
KANEMURA Naohiko 埼玉県立大学, 保健医療福祉学部, 講師 (20379895)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | リハビリテーション医学 / シナプス / ダルタミン酸受容体 / バランス / 運動 / 学習 / グルタミン酸受容体 |
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| Research Abstract |
The effects of aging and balance exercise on the expression and the modification of synaptic receptors and neurotrophins in the cerebellum, the motor related-area, and the hippocampus were assessed using senescence-accelerated mice(SAM). High-frequent and long-time balance exercise for four weeks decreased the expression of synaptic receptors and neurotrophins, whereas low-frequent and short-time balance exercise for four weeks did not induce such down-regulation, and also increased the expression of synaptic receptors and the receptor of neurotrohin only in aged mice.
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