| Project/Area Number |
21500483
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Saitama Prefectural University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IMAGITA Hidetaka 畿央大学, 健康科学部, 教授 (00412148)
TAKEMOTO Hidenori 県立広島大学, 保健福祉学部, 助教 (10453218)
TAKAYANAGI Kiyomi 埼玉県立大学, 保健医療福祉学部, 教授 (20274061)
MORIYAMA Hideki 埼玉県立大学, 保健福祉学部, 講師 (10438111)
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| Co-Investigator(Renkei-kenkyūsha) |
MORIYAMA Hideki 広島大学, 大学院・保健学研究科, 講師 (10438111)
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| Research Collaborator |
KITO Nobuhiro 広島国際大学, 保健学研究科, 准教授 (40435061)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 老化 / 運動 / 感覚機能 / 老齢 / 廃用 |
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| Research Abstract |
The purpose of study is to analyze whether physical exercise enhanced the neural function in the knee joint with aging and disuse. Exercised rats showed a quantitative increase neurotrophin immunostaining that was mostly evident in the spinal cords. In biochemical assay, exercise increases selectively expression of neurotrophins and receptors mRNA in the lumber spinal cord in senescence. These results suggest that exercise enhanced neurotrophins and their receptors by physiological process that it is endogenous in the lumber spinal cords which innervate the knee joints.
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