Project/Area Number |
21500494
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Rehabilitation science/Welfare engineering
|
Research Institution | Tokyo Women's Medical University |
Principal Investigator |
UENO Atsuko 東京女子医科大学, 医学部, 助教 (30277199)
|
Co-Investigator(Kenkyū-buntansha) |
TOMIZAWA Yasuko 東京女子医科大学, 医学部, 助教 (00159047)
上塚 芳郎 東京女子医科大学, 医学部, 教授 (40147418)
|
Co-Investigator(Renkei-kenkyūsha) |
UETSUKA Yoshio 東京女子医科大学, 医学部, 教授 (40147418)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 大動脈弁閉鎖不全症 / 心肺運動負荷試験 / 運動耐容能 / 運動療法 / 心拍応答 / 心不全 / 予後 / 運動耐用能 / 予後予測 / 心機能低下 / 嫌気性代謝閾値 / BNP / 心筋障害 |
Research Abstract |
Severe aortic regurgitation(AR) patients show heart failure(HF). The prognosis of HF does not correlation with left ventricular ejection fraction(LVEF). We examined exercise capacity and heart rate response by cardiopulmonary exercise testings to patients with heart failure including patients with aortic regurgitation, and also predicted their prognosis. As a result, we showed the positive correlation between peak O2 consumption and heart rate response. The case showed that whose heart rate decreased at rest by optimal exercise therapy. Therefore we suggested the possibility that exercise therapy improve exercise capacity for the patients with heart failure.
|