Reseach on recovery of blood pressure regulating hormone after exercise and training effect

• Project/Area Number: 21500626
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sports science
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: SUDA Kazuhiro 東京工業大学, 大学院・社会理工学研究科, 准教授 (70192135)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: スポーツ生理学 / ANP / BNP / mRNA / ラット / 水泳 / RT-PCR / 心臓 / 酵素免疫測定法 / 心筋 / RIA / EIA

Research Abstract

Blood pressure regulating hormone concentration in heart and plasma after exercise were analyzed. Plasma ANP concentration increased and right atrial content was decreased in normotensive rats. Basal ANP concentration increased in hypertensive group and plasma ANP concentration decreased after exercise. Significant difference was not found in the content of the heart in the hypertensive group. Analysis of mRNA is on study because clear result was not obtained.