| Project/Area Number |
21500629
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Hiroyuki 金沢大学, 医学系, 教授 (30231476)
KAMBAYASHI Yasuhiro 金沢大学, 医学系, 講師 (20345630)
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| Co-Investigator(Renkei-kenkyūsha) |
HIBINO Yuri 金沢大学, 医学系, 助教 (40362008)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | スポーツ生化学 / 運動 / 姿勢保持 / 骨格筋 / 遺伝子組換動物 / 遺伝子発現 / ビタミンC / 遺伝子改変動物 / 酸化ストレス / 遺伝子組換え動物 |
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| Research Abstract |
We investigated the usability of transgenic animals, harboring a reporter gene encoding a short half-life reporter protein driven by the exercise-inducible promoter, on exercise and skeletal muscle study. The expression levels of reporter proteins were not necessarily enough to monitor the effect of exercise on individual muscle activity. However, these animals provide important insights in designing an exercise-reporter transgene to create an exercise-reporter transgenic animal.
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