Satellite cell activation to the change of muscle fiber size and the effects of motor nerve innervations and aging
| Project/Area Number |
21500633
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 熱ストレス / 再生筋線維 / 衛星細胞 / ミオシン重鎖 / ヒラメ筋 / ラット / 速筋線維 / 遅筋線維 / heat shock protein / 筋線維組成 / 速筋型ミオシン重鎖 / 遅筋型ミオシン重鎖 / Myo D |
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| Research Abstract |
Analyses were performed on the fiber phenotype expression, satellite cell activation, and the effects of heat stress at an early stage of rat soleus fiber regeneration. In heat stressed soleus regenerating fibers, slow type fiber containing only the slow myosin heavy chain isoform and enhanced activation of satellite cells were observed. These results suggest the possibility that heat stress accelerates the shift of fiber phenotype from fast to slow at an early stage of soleus fiber regenerating process.
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Report
(4 results)
Research Products
(17 results)
