| Project/Area Number |
21500634
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WADA Masanobu 広島大学, 大学院・総合科学研究科, 教授 (80220961)
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| Co-Investigator(Renkei-kenkyūsha) |
MISHIMA Takaaki 八戸学院大学, 人間健康学部, 准教授 (00461707)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | スポーツ生理学 / 伸張性収縮 / 筋収縮力 / 筋小胞体機能 / Na+・Kポンプ / 伸張性筋収縮 / Na^+-K^+-ATPase活性 / Ca^<2+>-ATPase活性 |
|---|
| Research Abstract |
To investigated whether the alterations in sarcoplasmic reticulum (SR) Ca2+handling function and excitability of sarcolemma would contribute to a loss of the contractile force following eccentric contraction (ECC), we examined contractile force, SR functions and sarcolemma Na+-K+-ATPase activity in ECC-stimulated rat hindlimb muscles. ECC resulted in force reductions, impaired capacity of Ca2+release by the SR and decreased Na+-K+-ATPase activity in rat. These results suggest that force developed by ECC-contracted muscle may be affected to a greater extent by diminished release of Ca2+from the SR and excitability of sarcolemma.
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